Cancer statistics in Japan―2024. Foundation for Promotion of Cancer Research. http://fpcr.or.jp/data_files/view/273/#toolbar=0&navpanes=0' (available PDF file in April 5th, 2025)

Lu MS, Chen MF, Lin CC, Tseng YH, Huang YK, Liu HP, et al. Is chronic kidney disease an adverse factor in lung cancer clinical outcome? A propensity score matching study. Thorac Cancer. 2017;8:106–13. https://doi.org/10.1111/1759-7714.12414.

Article  PubMed  PubMed Central  Google Scholar 

Iijima Y, Iwai S, Yamagata A, Motono N, Usuda K, Yamagishi S, et al. Is lung resection appropriate for late octogenarians? Surgical outcomes of patients aged ≥ 80 years with lung cancer. Clin Transl Oncol. 2021;23:1585–92. https://doi.org/10.1007/s12094-021-02554-4.

Article  CAS  PubMed  Google Scholar 

Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery, Shimizu H, Endo S, Natsugoe S, Doki Y, et al. Thoracic and cardiovascular surgery in Japan in 2016: annual report by the Japanese Association for Thoracic Surgery. Gen Thorac Cardiovasc Surg. 2019;67:377–411. https://doi.org/10.1007/s11748-019-01068-9.

Article  Google Scholar 

Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery, Yoshimura N, Sato Y, Takeuchi H, Abe T, et al. Thoracic and cardiovascular surgeries in Japan during 2022. Gen Thorac Cardiovasc Surg. 2025;73:254–94. https://doi.org/10.1007/s11748-024-02106-x.

Article  Google Scholar 

Sonoda D, Maruyama R, Kondo Y, Naito M, Mikubo M, Shiomi K, et al. Treatment selection pattern and prognostic factors in older patients with non-small cell lung cancer at recurrence: an observational study. Surg Today. 2025;55:588–99. https://doi.org/10.1007/s00595-024-02938-3.

Article  PubMed  Google Scholar 

Japanese Society of Nephrology. CKD medical care guide 2024. Tokyo: Tokyo Igaku-sha; 2024

Na SY, Sung JY, Chang JH, Kim S, Lee HH, Park YH, et al. Chronic kidney disease in cancer patients: an independent predictor of cancer-specific mortality. Am J Nephrol. 2011;33:121–30. https://doi.org/10.1159/000323740.

Article  PubMed  Google Scholar 

Iff S, Craig JC, Turner R, Chapman JR, Wang JJ, Mitchell P, et al. Reduced estimated GFR and cancer mortality. Am J Kidney Dis. 2014;63:23–30. https://doi.org/10.1053/j.ajkd.2013.07.008.

Article  PubMed  Google Scholar 

Dusselier M, Deluche E, Delacourt N, Ballouhey J, Egenod T, Melloni B, et al. Neutrophil-to-lymphocyte ratio evolution is an independent predictor of early progression of second-line nivolumab-treated patients with advanced non-small-cell lung cancers. PLoS ONE. 2019;14:e0219060. https://doi.org/10.1371/journal.pone.0219060.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brierley JD, Gospodarowicz MK, Wittekind C. UICC TNM Classification of malignant tumors. 8th ed. Hoboken: Wiley-Blackwell; 2016.

Google Scholar 

Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205–13. https://doi.org/10.1097/01.sla.0000133083.54934.ae.

Article  PubMed  PubMed Central  Google Scholar 

Yamamoto Y, Kanzaki R, Kanou T, Ose N, Funaki S, Minami M, et al. Long-term outcomes of pulmonary resection for lung cancer patients with chronic kidney disease. World J Surg. 2019;43:3249–58. https://doi.org/10.1007/s00268-019-05143-3.

Article  PubMed  Google Scholar 

Saito T, Murakawa T, Shintani Y, Okami J, Miyaoka E, Yoshino I, et al. Preoperative renal dysfunction and long-term survival after surgery for non small-cell lung cancer. J Thorac Cardiovasc Surg. 2022;164:227-239.e6. https://doi.org/10.1016/j.jtcvs.2021.09.008.

Article  PubMed  Google Scholar 

Liu WC, Zheng CM, Lu CL, Lin YF, Shyu JF, Wu CC, et al. Vitamin D and immune function in chronic kidney disease. Clin Chim Acta. 2015;450:135–44. https://doi.org/10.1016/j.cca.2015.08.011.

Article  CAS  PubMed  Google Scholar 

Kato S, Chmielewski M, Honda H, Pecoits-Filho R, Matsuo S, Yuzawa Y, et al. Aspects of immune dysfunction in end-stage renal disease. Clin J Am Soc Nephrol. 2008;3:1526–33. https://doi.org/10.2215/CJN.00950208.

Article  PubMed  PubMed Central  Google Scholar 

Stinghen AE, Bucharles S, Riella MC, Pecoits-Filho R. Immune mechanisms involved in cardiovascular complications of chronic kidney disease. Blood Purif. 2010;29:114–20. https://doi.org/10.1159/000245636.

Article  CAS  PubMed  Google Scholar 

Sung CC, Liao MT, Lu KC, Wu CC. Role of vitamin D in insulin resistance. J Biomed Biotechnol. 2012;2012:634195. https://doi.org/10.1155/2012/634195.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hung KC, Wu CC, Chen HS, Ma WY, Tseng CF, Yang LK, et al. Serum IL-6, albumin and co-morbidities are closely correlated with symptoms of depression in patients on maintenance haemodialysis. Nephrol Dial Transplant. 2011;26:658–64. https://doi.org/10.1093/ndt/gfq411.

Article  CAS  PubMed  Google Scholar 

Eleftheriadis T, Antoniadi G, Liakopoulos V, Kartsios C, Stefanidis I. Disturbances of acquired immunity in hemodialysis patients. Semin Dial. 2007;20:440–51. https://doi.org/10.1111/j.1525-139X.2007.00283.x.

Article  PubMed  Google Scholar 

Matas AJ, Simmons RL, Kjellstrand CM, Buselmeier TJ, Najarian JS. Increased incidence of malignancy during chronic renal failure. Lancet. 1975;1:883–6. https://doi.org/10.1016/s0140-6736(75)91684-0.

Article  CAS  PubMed  Google Scholar 

Kreft B, Klouche M, Kreft R, Kirchner H, Sack K. Low efficiency of active immunization against diphtheria in chronic hemodialysis patients. Kidney Int. 1997;52(1):212–6. https://doi.org/10.1038/ki.1997.322.

Article  CAS  PubMed  Google Scholar 

Kooman JP, Kotanko P, Schols AM, Shiels PG, Stenvinkel P. Chronic kidney disease and premature ageing. Nat Rev Nephrol. 2014;10:732–42. https://doi.org/10.1038/nrneph.2014.185.

Article  CAS  PubMed  Google Scholar 

Seth AK, De la Garza M, Fang RC, Hong SJ, Galiano RD. Excisional wound healing is delayed in a murine model of chronic kidney disease. PLoS ONE. 2013;8:e59979. https://doi.org/10.1371/journal.pone.0059979.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xie P, Young MW, Bian H, Niknam-Bienia S, Hong S, Mustoe TA, et al. Renal dysfunction aggravated impaired cutaneous wound healing in diabetic mice. Wound Repair Regen. 2019;27:49–58. https://doi.org/10.1111/wrr.12682.

Article  PubMed  Google Scholar 

Vassalotti JA, Francis A, Dos Santos ACS, Correa-Rotter R, Abdellatif D, Hsiao LL, et al. Are your kidneys ok? Detect early to protect kidney health. Am J Hypertens. 2025;38:612–9. https://doi.org/10.1093/ajh/hpaf062.

Article  PubMed  PubMed Central  Google Scholar 

Masaki T, Hanafusa N, Abe M, Joki N, Hoshino J, Taniguchi M, et al. 2023 Annual dialysis data report, JSDT renal data registry. J Jpn Soc Dial Ther. 2024;57:543–620.

Article  Google Scholar 

Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296–305. https://doi.org/10.1056/NEJMoa041031.

Article  CAS  PubMed  Google Scholar 

Ishii T, Fujimaru T, Nakano E, Takahashi O, Nakayama M, Yamauchi T, et al. Association between chronic kidney disease and mortality in stage IV cancer. Int J Clin Oncol. 2020;25:1587–95. https://doi.org/10.1007/s10147-020-01715-9.

Article  PubMed  Google Scholar