A comprehensive review on Moringa oleifera nanoparticles: importance of polyphenols in nanoparticle synthesis, nanoparticle efficacy and their applications

Devkota HP, Gaire BP, Hori K, Subedi L, Adhikari-Devkota A, Belwal T, et al. The science of matcha: bioactive compounds, analytical techniques and biological properties. Trends Food Sci Technol. 2021;118:735–43.

Article  CAS  Google Scholar 

Nunes DAD, Salgado AM, da Gama-Rodrigues EF, Taketani RG, da Cunha CD, Sérvulo EFC. Use of plant materials for the bioremediation of soil from an industrial site. J Environ Sci Heal Part A. 2020;55:650–60. https://doi.org/10.1080/10934529.2020.1726695.

Article  CAS  Google Scholar 

Srikar S, Giri D, Pal D, Mishra P, Upadhyay S. Green synthesis of silver nanoparticles: a review. Green Sustain Chem. 2016;6:34–56. https://doi.org/10.4236/gsc.2016.61004.

Article  CAS  Google Scholar 

Bindhu MR, Umadevi M, Esmail GA, Al-Dhabi NA, Arasu MV. Green synthesis and characterization of silver nanoparticles from Moringa oleifera flower and assessment of antimicrobial and sensing properties. J Photochem Photobiol B Biol. 2020;205:111836. https://doi.org/10.1016/j.jphotobiol.2020.111836.

Article  CAS  Google Scholar 

Ezhilarasi AA, Vijaya JJ, Kaviyarasu K, Maaza M, Ayeshamariam A, Kennedy LJ. Green synthesis of NiO nanoparticles using Moringa oleifera extract and their biomedical applications: cytotoxicity effect of nanoparticles against HT-29 cancer cells. J Photochem Photobiol B Biol. 2016;164:352–60. https://doi.org/10.1016/j.jphotobiol.2016.10.003.

Article  CAS  Google Scholar 

Shahbazi MA, Faghfouri L, Ferreira MPA, Figueiredo P, Maleki H, Sefat F, et al. The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties. Chem Soc Rev. 2020;49:1253–321.

Article  CAS  PubMed  Google Scholar 

Rabiee N, Bagherzadeh M, Kiani M, Ghadiri AM, Etessamifar F, Jaberizadeh AH, et al. Biosynthesis of copper oxide nanoparticles with potential biomedical applications. Int J Nanomed. 2020;15:3983–99.

Article  CAS  Google Scholar 

Abel S, Tesfaye JL, Nagaprasad N, Shanmugam R, Dwarampudi LP, Krishnaraj R. Synthesis and characterization of zinc oxide nanoparticles using Moringa leaf extract. J Nanomater. 2021;2021:4525770. https://doi.org/10.1155/2021/4525770.

Article  CAS  Google Scholar 

Kaittanis C, Santra S, Asati A, Perez JM. A cerium oxide nanoparticle-based device for the detection of chronic inflammation via optical and magnetic resonance imaging. Nanoscale. 2012;4:2117–23.

Article  ADS  CAS  PubMed  Google Scholar 

Irfan M, Munir H, Ismail H. Moringa oleifera gum based silver and zinc oxide nanoparticles: green synthesis, characterization and their antibacterial potential against MRSA. Biomater Res. 2021;25:17. https://doi.org/10.1186/s40824-021-00219-5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gomez C, Hallot G, Pastor A, Laurent S, Brun E, Sicard-Roselli C, et al. Metallic bismuth nanoparticles: towards a robust, productive and ultrasound assisted synthesis from batch to flow-continuous chemistry. Ultrason Sonochem. 2019;56:167–73. https://doi.org/10.1016/j.ultsonch.2019.04.012.

Article  CAS  PubMed  Google Scholar 

Katata-Seru L, Moremedi T, Aremu OS, Bahadur I. Green synthesis of iron nanoparticles using Moringa oleifera extracts and their applications: removal of nitrate from water and antibacterial activity against Escherichia coli. J Mol Liq. 2018;256:296–304. https://doi.org/10.1016/j.molliq.2017.11.093.

Article  CAS  Google Scholar 

Khor KZ, Joseph J, Shamsuddin F, Lim V, Moses EJ, Samad NA. The cytotoxic effects of moringa oleifera leaf extract and silver nanoparticles on human kasumi-1 cells. Int J Nanomed. 2020;15:5661–70.

Article  CAS  Google Scholar 

Mehwish HM, Rajoka MSR, Xiong Y, Cai H, Aadil RM, Mahmood Q, et al. Green synthesis of a silver nanoparticle using Moringa oleifera seed and its applications for antimicrobial and sun-light mediated photocatalytic water detoxification. J Environ Chem Eng. 2021;9:105290. https://doi.org/10.1016/j.jece.2021.105290.

Article  CAS  Google Scholar 

Moodley JS, Krishna SBN, Pillay K, Sershen Govender P. Green synthesis of silver nanoparticles from Moringa oleifera leaf extracts and its antimicrobial potential. Adv Nat Sci Nanosci Nanotechnol. 2018;9:015011.

Article  ADS  Google Scholar 

Narendhran S, Manikandan M, Baby SP. Antibacterial, antioxidant properties of Solanum trilobatum and sodium hydroxide-mediated magnesium oxide nanoparticles: a green chemistry approach. Bull Mater Sci. 2019. https://doi.org/10.1007/s12034-019-1811-7.

Article  Google Scholar 

Ponnanikajamideen M, Rukumani V, Paulkumar K, Vanaja M, Samuel Rajendran R, Annadurai G. Moringa oleifera gum mediated fabrication of gold nanoparticles for effective DNA protection. J Bionanoscience. 2017;11:52–8.

Article  CAS  Google Scholar 

Pugazhendhi A, Prabhu R, Muruganantham K, Shanmuganathan R, Natarajan S. Anticancer, antimicrobial and photocatalytic activities of green synthesized magnesium oxide nanoparticles (MgONPs) using aqueous extract of Sargassum wightii. J Photochem Photobiol B Biol. 2019;190:86–97. https://doi.org/10.1016/j.jphotobiol.2018.11.014.

Article  CAS  Google Scholar 

Rivas-San Vicente M, Plasencia J. Salicylic acid beyond defence: Its role in plant growth and development. J Exp Bot. 2011;62:3321–38.

Article  CAS  PubMed  Google Scholar 

Rivas R, Oliveira MT, Santos MG. Three cycles of water deficit from seed to young plants of Moringa oleifera woody species improves stress tolerance. Plant Physiol Biochem. 2013;63:200–8.

Article  CAS  PubMed  Google Scholar 

Anwar F, Latif S, Ashraf M, Gilani AH. Moringa oleifera: a food plant with multiple medicinal uses. Phyther Res. 2007;21:17–25. https://doi.org/10.1002/ptr.2023.

Article  CAS  Google Scholar 

Leone A, Spada A, Battezzati A, Schiraldi A, Aristil J, Bertoli S. Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an overview. Int J Mol Sci. 2015;16:12791–835.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Paikra BK, Dhongade HKJ, Gidwani B. Phytochemistry and pharmacology of Moringa oleifera lam. J pharmacopuncture. 2017;20:194–200.

Article  PubMed  PubMed Central  Google Scholar 

Saa RW, Fombang EN, Ndjantou EB, Njintang NY. Treatments and uses of Moringa oleifera seeds in human nutrition: a review. Food Sci Nutr. 2019;7:1911–9. https://doi.org/10.1002/fsn3.1057.

Article  PubMed  PubMed Central  Google Scholar 

Ueda Yamaguchi N, Cusioli LF, Quesada HB, Camargo Ferreira ME, Fagundes-Klen MR, Salcedo Vieira AM, et al. A review of Moringa oleifera seeds in water treatment: trends and future challenges. Process Saf Environ Prot. 2021;147:405–20.

Article  CAS  Google Scholar 

Baptista ATA, Coldebella PF, Cardines PHF, Gomes RG, Vieira MF, Bergamasco R, et al. Coagulation–flocculation process with ultrafiltered saline extract of Moringa oleifera for the treatment of surface water. Chem Eng J. 2015;276:166–73.

Article  CAS  Google Scholar 

dos Santos BS, Eyng E, Bittencourt PRS, Frare LM, de Flores ÉLM, Costa M. Electro-flocculation associated with the extract of Moringa oleifera Lam as natural coagulant for the removal of reactive blue 5G dye. Acta Sci Pol Hortorum Cultus Technol. 2016;38:483–8. https://doi.org/10.4025/actascitechnol.v38i4.28796.

Article  CAS  Google Scholar 

Fahey JR. Microbiological monitoring of laboratory mice. In: Sundberg J, editor. Genetically engineered mice handbook. Boca Raton: CRC Press; 2016. p. 157–64.

Google Scholar 

Mahmood KT, Mugal T, Haq IU. Moringa oleifera: a natural gift-a review. J Pharm Sci Res. 2010;2:775–81.

Google Scholar 

Ferreira PMP, Farias DF, de Oliveira JTA, de Carvalho AFU. Moringa oleifera: bioactive compounds and nutritional potential. Rev Nutr Scielo. 2008. https://doi.org/10.1590/S1415-52732008000400007.

Article  Google Scholar 

Busani M, Patrick JM, Arnold H, Voster M. Nutritional characterization of Moringa (Moringa oleifera Lam.) leaves. Afr J Biotechnol. 2011;10:12925–33. https://doi.org/10.5897/AJB10.1599.

Article  Google Scholar 

Mahfuz S, Piao XS. Application of moringa (Moringa oleifera) as natural feed supplement in poultry diets. Animals. 2019;9:431.

Article  PubMed  PubMed Central  Google Scholar 

Shousha WG, Aboulthana WM, Salama AH, Saleh MH, Essawy EA. Evaluation of the biological activity of Moringa oleifera leaves extract after incorporating silver nanoparticles, in vitro study. Bull Natl Res Cent. 2019. https://doi.org/10.1186/s42269-019-0221-8.

Article  Google Scholar 

El-Khadragy M, Alolayan EM, Metwally DM, El-Din MFS, Alobud SS, Alsultan NI, et al. Clinical efficacy associated with enhanced antioxidant enzyme activities of silver nanoparticles biosynthesized using moringa oleifera leaf extract, against cutaneous leishmaniasis in a murine model of leishmania major. Int J Environ Res Public Health. 2018;15:1037.

Article  PubMed  PubMed Central  Google Scholar 

Aisida SO, Ugwoke E, Uwais A, Iroegbu C, Botha S, Ahmad I, et al. Incubation period induced biogenic synthesis of PEG enhanced Moringa oleifera silver nanocapsules and its antibacterial activity. J Polym Res. 2019. https://doi.org/10.1007/s10965-019-1897-z.

Article  Google Scholar 

Paul S, Basak P, Majumder R, Mukherjee A, Ghosh J, Patra S, et al. Biochemical estimation of Moringa oleifera leaf extract for synthesis of silver nanoparticle mediated drug delivery system. J Plant Biochem Biotechnol. 2020;29:86–93. https://doi.org/10.1007/s13562-019-00517-z.

Article  CAS  Google Scholar 

Vasanth K, Ilango K, MohanKumar R, Agrawal A, Dubey GP. Anticancer activity of Moringa oleifera mediated silver nanoparticles on human cervical carcinoma cells by apoptosis induction. Colloids Surf B Biointerfaces. 2014;117:354–9. https://doi.org/10.1016/j.colsurfb.2014.02.052.

Article  CAS  PubMed  Google Scholar 

Comments (0)

No login
gif