Luciferase Reporter Assay for Determining the Signaling Activity of Interferons

Alam J, Cook JL (1990) Reporter genes: application to the study of mammalian gene transcription. Anal Biochem 188:245–254

Article  CAS  PubMed  Google Scholar 

East AK, Mauchline TH, Poole PS (2008) Biosensors for ligand detection. Adv Appl Microbiol 64:137–166

Article  CAS  PubMed  Google Scholar 

Montefiori DC (2009) Measuring HIV neutralization in a luciferase reporter gene assay. Methods Mol Biol 485:395–405

Article  CAS  PubMed  Google Scholar 

Ghim CM, Lee SK, Takayama S, Mitchell RJ (2010) The art of reporter proteins in science: past, present and future applications. BMB Rep 43:451–460

Article  CAS  PubMed  Google Scholar 

Jacobson RH, Zhang XJ, DuBose RF, Matthews BW (1994) Three-dimensional structure of beta-galactosidase from E. coli. Nature 369:761–766

Article  CAS  PubMed  Google Scholar 

Fowler AV, Zabin I (1983) Purification, structure, and properties of hybrid beta-galactosidase proteins. J Biol Chem 258:14354–14358

Article  CAS  PubMed  Google Scholar 

Shimomura O, Johnson FH, Saiga Y (1962) Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea. J Cell Comp Physiol 59:223–239

Article  CAS  PubMed  Google Scholar 

Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC (1994) Green fluorescent protein as a marker for gene expression. Science 263:802–805

Article  CAS  PubMed  Google Scholar 

Chudakov DM, Matz MV, Lukyanov S, Lukyanov KA (2010) Fluorescent proteins and their applications in imaging living cells and tissues. Physiol Rev 90:1103–1163

Article  CAS  PubMed  Google Scholar 

Gould SJ, Subramani S (1988) Firefly luciferase as a tool in molecular and cell biology. Anal Biochem 175:5–13

Article  CAS  PubMed  Google Scholar 

Himes SR, Shannon MF (2000) Assays for transcriptional activity based on the luciferase reporter gene. Methods Mol Biol 130:165–174

CAS  PubMed  Google Scholar 

Dyer BW, Ferrer FA, Klinedinst DK, Rodriguez R (2000) A noncommercial dual luciferase enzyme assay system for reporter gene analysis. Anal Biochem 282:158–161

Article  CAS  PubMed  Google Scholar 

de Wet JR, Wood KV, DeLuca M, Helinski DR, Subramani S (1987) Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol 7:725–737

PubMed  PubMed Central  Google Scholar 

DeLuca M, McElroy WD (1984) Two kinetically distinguishable ATP sites in firefly luciferase. Biochem Biophys Res Commun 123:764–770

Article  CAS  PubMed  Google Scholar 

Shifera AS, Hardin JA (2010) Factors modulating expression of Renilla luciferase from control plasmids used in luciferase reporter gene assays. Anal Biochem 396:167–172

Article  CAS  PubMed  Google Scholar 

Thompson JF, Hayes LS, Lloyd DB (1991) Modulation of firefly luciferase stability and impact on studies of gene regulation. Gene 103:171–177

Article  CAS  PubMed  Google Scholar 

Boulay JL, O’Shea JJ, Paul WE (2003) Molecular phylogeny within type I cytokines and their cognate receptors. Immunity 19:159–163

Article  CAS  PubMed  Google Scholar 

Pestka S (2007) The interferons: 50 years after their discovery, there is much more to learn. J Biol Chem 282:20047–20051

Article  CAS  PubMed  Google Scholar 

Barral PM, Sarkar D, Su ZZ, Barber GN, DeSalle R, Racaniello VR, Fisher PB (2009) Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: key regulators of innate immunity. Pharmacol Ther 124:219–234

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tovey MG, Lallemand C, Thyphronitis G (2008) Adjuvant activity of type I interferons. Biol Chem 389:541–545

Article  CAS  PubMed  Google Scholar 

Content J (2009) Mechanisms of induction and action of interferons. Verh K Acad Geneeskd Belg 71:51–71

CAS  PubMed  Google Scholar 

Ivashkiv LB, Donlin LT (2014) Regulation of type I interferon responses. Nat Rev Immunol 14:36–49

Article  CAS  PubMed  PubMed Central  Google Scholar 

McNab F, Mayer-Barber K, Sher A, Wack A, O’Garra A (2015) Type I interferons in infectious disease. Nat Rev Immunol 15:87–103

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tovey MG, Lallemand C (2010) Safety, tolerability, and immunogenicity of interferons. Pharmaceuticals (Basel) 3:1162–1186

Article  CAS  PubMed  Google Scholar 

Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW (2002) Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285:1–24

Article  CAS  PubMed  Google Scholar 

MacMicking JD (2012) Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat Rev Immunol 12:367–382

Article  CAS  PubMed  PubMed Central  Google Scholar 

Reich N, Evans B, Levy D, Fahey D, Knight E Jr, Darnell JE Jr (1987) Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci USA 84:6394–6398

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schoggins JW, Rice CM (2011) Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol 1:519–525

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng Q, Miao Y, Ge J, Yuan Y, Zuo Y, Qian L, Liu J, Cheng Q, Guo T, Zhang L, Yu Z, Zheng H (2018) ATXN3 positively regulates type I IFN antiviral response by deubiquitinating and stabilizing HDAC3. J Immunol 201:675–687

Article  CAS  PubMed  Google Scholar 

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