Benedict RHB, Amato MP, Deluca J et al (2020) Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenues. Lancet Neurol 19:860–871
PubMed PubMed Central Google Scholar
Meca-Lallana V, Gascon-Gimenez F, Ginestal-Lopez RC et al (2021) Cognitive impairment in multiple sclerosis: diagnosis and monitoring. Neurol Sci 42:5183–5193
PubMed PubMed Central Google Scholar
Vaughn CB, Jakimovski D, Kavak KS et al (2019) Epidemiology and treatment of multiple sclerosis in elderly populations. Nat Rev Neurol 15:329–342
Magliozzi R, Reynolds R, Calabrese M (2018) MRI of cortical lesions and its use in studying their role in MS pathogenesis and disease course. Brain Pathol 28:735–742
CAS PubMed PubMed Central Google Scholar
Nelson F, Datta S, Garcia N et al (2011) Intracortical lesions by 3T magnetic resonance imaging and correlation with cognitive impairment in multiple sclerosis. Mult Scler 17:1122–1129
PubMed PubMed Central Google Scholar
Calabrese M, Agosta F, Rinaldi F et al (2009) Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis. Arch Neurol 66:1144–1150
Mike A, Glanz BI, Hildenbrand P et al (2011) Identification and clinical impact of multiple sclerosis cortical lesions as assessed by routine 3T MR imaging. AJNR Am J Neuroradiol 32:515–521
CAS PubMed PubMed Central Google Scholar
Papadopoulou A, Müller-Lenke N, Naegelin Y et al (2013) Contribution of cortical and white matter lesions to cognitive impairment in multiple sclerosis. Mult Scler 19:1290–1296
Roosendaal SD, Moraal B, Pouwels PJ et al (2009) Accumulation of cortical lesions in MS: relation with cognitive impairment. Mult Scler 15:708–714
Kidd D, Barkhof F, Mcconnell R et al (1999) Cortical lesions in multiple sclerosis. Brain 122(Pt 1):17–26
Calabrese M, Filippi M, Gallo P (2010) Cortical lesions in multiple sclerosis. Nat Rev Neurol 6:438–444
Nociti V, Romozzi M, Mirabella M (2024) Challenges in Diagnosis and Therapeutic Strategies in Late-Onset Multiple Sclerosis. J Pers Med 14
Alroughani R, Akhtar S, Ahmed S et al. (2016) Is Time to Reach EDSS 6.0 Faster in Patients with Late-Onset versus Young-Onset Multiple Sclerosis? PLoS One 11:e0165846
Lorefice L, Ferraro OE, Fenu G et al (2024) Late-onset multiple sclerosis: disability trajectories in relapsing-remitting patients of the Italian MS Registry. J Neurol 271:1630–1637
Lotti CBC, Oliveira ASB, Bichuetti DB et al (2017) Late onset multiple sclerosis: concerns in aging patients. Arq Neuropsiquiatr 75:451–456
Oliveira AI, Monteiro IR, Alferes AR et al (2024) Cognitive outcomes in late-onset versus adult-onset Multiple Sclerosis. Mult Scler Relat Disord 90:105845
Holtzer R, Choi J, Motl RW et al (2023) Individual reserve in aging and neurological disease. J Neurol 270:3179–3191
PubMed PubMed Central Google Scholar
Thompson AJ, Banwell BL, Barkhof F et al (2018) Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol 17:162–173
Geurts JJ, Roosendaal SD, Calabrese M et al (2011) Consensus recommendations for MS cortical lesion scoring using double inversion recovery MRI. Neurology 76:418–424
Schmidt P, Gaser C, Arsic M et al (2012) An automated tool for detection of FLAIR-hyperintense white-matter lesions in Multiple Sclerosis. Neuroimage 59:3774–3783
Deluca J, Schippling S, Montalban X et al (2021) Effect of Ozanimod on Symbol Digit Modalities Test Performance in Relapsing MS. Mult Scler Relat Disord 48:102673
Roxburgh RH, Seaman SR, Masterman T et al (2005) Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity. Neurology 64:1144–1151
Mouresan EF, Mentesidou E, Berglund A et al (2024) Clinical Characteristics and Long-Term Outcomes of Late-Onset Multiple Sclerosis: A Swedish Nationwide Study. Neurology 102:e208051
CAS PubMed PubMed Central Google Scholar
Dimauro KA, Swetlik C, Cohen JA (2024) Management of multiple sclerosis in older adults: review of current evidence and future perspectives. J Neurol 271:3794–3805
PubMed PubMed Central Google Scholar
Holtzer R, Verghese J, Wang C et al (2008) Within-person across-neuropsychological test variability and incident dementia. JAMA 300:823–830
CAS PubMed PubMed Central Google Scholar
Torrence ND, John SE, Gavett BE et al (2016) An Empirical Comparison of Competing Factor Structures for the Repeatable Battery for the Assessment of Neuropsychological Status: A Project FRONTIER Study. Arch Clin Neuropsychol 31:88–96
Learmonth YC, Motl RW, Sandroff BM et al (2013) Validation of patient determined disease steps (PDDS) scale scores in persons with multiple sclerosis. BMC Neurol 13:37
PubMed PubMed Central Google Scholar
Calabrese M, De Stefano N, Atzori M et al (2007) Detection of cortical inflammatory lesions by double inversion recovery magnetic resonance imaging in patients with multiple sclerosis. Arch Neurol 64:1416–1422
Calabrese M, Rocca MA, Atzori M et al (2010) A 3-year magnetic resonance imaging study of cortical lesions in relapse-onset multiple sclerosis. Ann Neurol 67:376–383
Parra Corral MA, Govindarajan ST, Stefancin P et al (2019) Characterization of gray-matter multiple sclerosis lesions using double inversion recovery, diffusion, contrast-enhanced, and volumetric MRI. Mult Scler Relat Disord 31:74–81
Faizy TD, Broocks G, Thaler C et al (2019) Development of Cortical Lesion Volumes on Double Inversion Recovery MRI in Patients With Relapse-Onset Multiple Sclerosis. Front Neurol 10:133
PubMed PubMed Central Google Scholar
Damasceno A, Damasceno BP, Cendes F (2014) The clinical impact of cerebellar grey matter pathology in multiple sclerosis. PLoS ONE 9:e96193
PubMed PubMed Central Google Scholar
Santangelo G, Altieri M, Gallo A et al (2019) Does cognitive reserve play any role in multiple sclerosis? A meta-analytic study. Mult Scler Relat Disord 30:265–276
Sandry J, Simonet DV, Brandstadter R et al (2021) The Symbol Digit Modalities Test (SDMT) is sensitive but non-specific in MS: Lexical access speed, memory, and information processing speed independently contribute to SDMT performance. Mult Scler Relat Disord 51:102950
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