Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med. 2001;345(11):784–9.
Article CAS PubMed Google Scholar
Watari J, Chen N, Amenta PS, Fukui H, Oshima T, Tomita T, et al. Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development. World J Gastroenterol. 2014;20(18):5461–73.
Article CAS PubMed PubMed Central Google Scholar
Malfertheiner P, Megraud F, O’Morain CA, Gisbert JP, Kuipers EJ, Axon AT, et al. Management of helicobacter pylori infection–the maastricht V/florence consensus report. Gut. 2017;66(1):6–30.
Article CAS PubMed Google Scholar
Wang J, Xu L, Shi R, Huang X, Li SWH, Huang Z, et al. Gastric atrophy and intestinal metaplasia before and after Helicobacter pylori eradication: a meta-analysis. Digestion. 2011;83(4):253–60.
Xiong H, Du W, Sun TT, Lin YW, Wang JL, Hong J, et al. A positive feedback loop between STAT3 and cyclooxygenase-2 gene may contribute to Helicobacter pylori-associated human gastric tumorigenesis. Int J Cancer. 2014;134(9):2030–40.
Article CAS PubMed Google Scholar
Song X, Xin N, Wang W, Zhao C. Wnt/β-catenin, an oncogenic pathway targeted by H. pylori in gastric carcinogenesis. Oncotarget. 2015;6(34):35579–88.
Article PubMed PubMed Central Google Scholar
Zhao J, Dong Y, Kang W, Go MY, Tong JH, Ng EK, et al. Helicobacter pylori-induced STAT3 activation and signalling network in gastric cancer. Oncoscience. 2014;1(6):468–75.
Article PubMed PubMed Central Google Scholar
Suzuki M, Mimuro H, Kiga K, Fukumatsu M, Ishijima N, Morikawa H, et al. Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation. Cell Host Microbe. 2009;5(1):23–34.
Article CAS PubMed Google Scholar
Tabassam FH, Graham DY, Yamaoka Y. Helicobacter pylori activate epidermal growth factor receptor and phosphatidylinositol 3-OH kinase-dependent Akt and glycogen synthase kinase 3beta phosphorylation. Cell Microbiol. 2009;11(1):70–82.
Article CAS PubMed Google Scholar
Ito K, Chuang LS, Ito T, Chang TL, Fukamachi H, Salto-Tellez M, et al. Loss of Runx3 is a key event in inducing precancerous state of the stomach. Gastroenterology. 2011;140(5):1536-46.e8.
Article CAS PubMed Google Scholar
Soutto M, Peng D, Katsha A, Chen Z, Piazuelo MB, Washington MK, et al. Activation of β-catenin signaling by TFF1 loss promotes cell proliferation and gastric tumorigenesis. Gut. 2015;64(7):1028–39.
Article CAS PubMed Google Scholar
Nuñez F, Bravo S, Cruzat F, Montecino M, De Ferrari GV. Wnt/β-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells. PLoS ONE. 2011;6(4):e18562.
Article PubMed PubMed Central Google Scholar
Yang HB, Cheng HC, Sheu BS, Hung KH, Liou MF, Wu JJ. Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication. Aliment Pharmacol Ther. 2007;25(4):455–61.
Article CAS PubMed Google Scholar
Hung KH, Yang HB, Cheng HC, Wu JJ, Sheu BS. Short-term celecoxib to regress long-term persistent gastric intestinal metaplasia after Helicobacter pylori eradication. J Gastroenterol Hepatol. 2010;25(1):48–53.
Article CAS PubMed Google Scholar
Hung KH, Wu JJ, Yang HB, Su LJ, Sheu BS. Host Wnt/beta-catenin pathway triggered by Helicobacter pylori correlates with regression of gastric intestinal metaplasia after H. pylori eradication. J Med Microbiol. 2009;58(Pt 5):567–76.
Article CAS PubMed Google Scholar
Yang YJ, Chuang CC, Yang HB, Lu CC, Sheu BS. Lactobacillus acidophilus ameliorates H. pylori-induced gastric inflammation by inactivating the Smad7 and NFκB pathways. BMC Microbiol. 2012;12:38.
Article CAS PubMed PubMed Central Google Scholar
Yang YJ, Sheu BS. Probiotics-containing yogurts suppress H. pylori load, and modify immune response & intestinal microbiota in the H. pylori-infected children. Helicobacter. 2012;17(4):297–304.
Article CAS PubMed Google Scholar
Brzozowski T, Konturek PC, Mierzwa M, Drozdowicz D, Bielanski W, Kwiecien S, et al. Effect of probiotics and triple eradication therapy on the cyclooxygenase (COX)-2 expression, apoptosis, and functional gastric mucosal impairment in Helicobacter pylori-infected Mongolian gerbils. Helicobacter. 2006;11(1):10–20.
Article CAS PubMed Google Scholar
Duary RK, Bhausaheb MA, Batish VK, Grover S. Anti-inflammatory and immunomodulatory efficacy of indigenous probiotic Lactobacillus plantarum Lp91 in colitis mouse model. Mol Biol Rep. 2012;39(4):4765–75.
Article CAS PubMed Google Scholar
Zhu Y, Jiang Q, Lou X, Ji X, Wen Z, Wu J, et al. MicroRNAs up-regulated by CagA of Helicobacter pylori induce intestinal metaplasia of gastric epithelial cells. PLoS ONE. 2012;7(4):e35147.
Article CAS PubMed PubMed Central Google Scholar
Sousa JF, Nam KT, Petersen CP, Lee HJ, Yang HK, Kim WH, Goldenring JR. miR-30-HNF4γ and miR-194-NR2F2 regulatory networks contribute to the upregulation of metaplasia markers in the stomach. Gut. 2016;65(6):914–24.
Article CAS PubMed Google Scholar
Fassan M, Saraggi D, Balsamo L, Realdon S, Scarpa M, Castoro C, et al. Early miR-223 upregulation in gastroesophageal carcinogenesis. Am J Clin Pathol. 2017;147(3):301–8.
Article CAS PubMed Google Scholar
Sun R, Liu Z, Tong D, Yang Y, Guo B, Wang X, et al. miR-491-5p, mediated by Foxi1, functions as a tumor suppressor by targeting Wnt3a/β-catenin signaling in the development of gastric cancer. Cell Death Dis. 2017;8(3):e2714.
Article PubMed PubMed Central Google Scholar
Dong L, Deng J, Sun ZM, Pan AP, Xiang XJ, Zhang L, et al. Interference with the β-catenin gene in gastric cancer induces changes to the miRNA expression profile. Tumour Biol. 2015;36(9):6973–83.
Article CAS PubMed Google Scholar
Cong N, Du P, Zhang A, Shen F, Su J, Pu P, et al. Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma. Oncol Rep. 2013;29(4):1579–87.
Article CAS PubMed Google Scholar
Kao CY, Chen JW, Huang YT, Sheu SM, Sheu BS, Wu JJ. Genome sequence and annotation of Helicobacter pylori strain Hp238, isolated from a Taiwanese patient with mucosa-associated lymphoid tissue lymphoma. Genome Announc. 2015;3(1):e00006-e00015.
Article PubMed PubMed Central Google Scholar
Howlett M, Giraud AS, Lescesen H, Jackson CB, Kalantzis A, Van Driel IR, et al. The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development. Gastroenterology. 2009;136(3):967–77.
Article CAS PubMed Google Scholar
Balic JJ, Saad MI, Dawson R, West AJ, McLeod L, West AC, et al. Constitutive STAT3 serine phosphorylation promotes Helicobacter-mediated gastric disease. Am J Pathol. 2020;190(6):1256–70.
Article CAS PubMed Google Scholar
Piao JY, Lee HG, Kim SJ, Kim DH, Han HJ, Ngo HKC, et al. Helicobacter pylori activates IL-6-STAT3 signaling in human gastric cancer cells: potential roles for reactive oxygen species. Helicobacter. 2016;21(5):405–16.
Comments (0)