Chung ST, Onuzuruike AU, Magge SN. Cardiometabolic risk in obese children. Ann N Y Acad Sci. 2018;1411:166–83.
PubMed PubMed Central Google Scholar
Jazayeri S, Heshmati J, Mokhtari Z, Sepidarkish M, Nameni G, Potter E, Zaroudi M. Effect of omega-3 fatty acids supplementation on anthropometric indices in children and adolescents: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2020;53:102487.
Drozdz D, Alvarez-Pitti J, Wójcik M, Borghi C, Gabbianelli R, Mazur A, Herceg-Čavrak V, Lopez-Valcarcel BG, Brzeziński M, Lurbe E. Obesity and cardiometabolic risk factors: from childhood to adulthood. Nutrients. 2021;13:4176.
PubMed PubMed Central Google Scholar
Organization WH. Report of the commission on ending childhood obesity. World Health Organization; 2016.
Howe P, Buckley J. Metabolic health benefits of long-chain omega-3 polyunsaturated fatty acids. Mil Med. 2014;179:138–43.
Bonafini S, Antoniazzi F, Maffeis C, Minuz P, Fava C. Beneficial effects of ω-3 PUFA in children on cardiovascular risk factors during childhood and adolescence. Prostaglandins Other Lipid Mediat. 2015;120:72–9.
Curioni CC, Alves NNR, Zago L. Omega-3 supplementation in the treatment of overweight and obese children and adolescents: A systematic review. J Funct Foods. 2019;52:340–7.
Pederiva C, Capra ME, Viggiano C, Rovelli V, Banderali G, Biasucci G. Early prevention of atherosclerosis: detection and management of hypercholesterolaemia in children and adolescents. Life. 2021;11:345.
CAS PubMed PubMed Central Google Scholar
Paduchová Z, Katrenčíková B, Vaváková M, Laubertová L, Nagyová Z, Garaiova I, Ďuračková Z, Trebatická J. The effect of omega-3 fatty acids on thromboxane, brain-derived neurotrophic factor, homocysteine, and vitamin D in depressive children and adolescents: randomized controlled trial. Nutrients. 2021;13:1095.
PubMed PubMed Central Google Scholar
Juárez-López C, Klünder‐Klünder M, Madrigal‐Azcárate A, Flores‐Huerta S. Omega‐3 polyunsaturated fatty acids reduce insulin resistance and triglycerides in obese children and adolescents. Pediatr Diabetes. 2013;14:377–83.
Ahmadi A, Gharipour M, Arabzadeh G, Moin P, Hashemipour M, Kelishadi R. The effects of vitamin E and Omega-3 PUFAs on endothelial function among adolescents with metabolic syndrome. Biomed Res Int. 2014;2014:906019.
PubMed PubMed Central Google Scholar
Khorshidi M, Sayyari A, Aryaeian N, Olang B, Alaei M, Khalili M, Hosseini A, Salehi M. Effects of omega-3 supplementation on endothelial function, vascular structure, and metabolic parameters in adolescents with type 1 diabetes mellitus: A randomized clinical trial. Front Nutr. 2022;9:962773.
PubMed PubMed Central Google Scholar
Izadi A, Khedmat L, Tavakolizadeh R, Mojtahedi SY. The intake assessment of diverse dietary patterns on childhood hypertension: alleviating the blood pressure and lipidemic factors with low-sodium seafood rich in omega-3 fatty acids. Lipids Health Dis. 2020;19:1–13.
O’sullivan T, Bremner A, Beilin L, Ambrosini GL, Mori T, Huang R-C, Oddy WH. Polyunsaturated fatty acid intake and blood pressure in adolescents. J Hum Hypertens. 2012;26:178–87.
Agostoni C, Braegger C, Decsi T, Kolacek S, Mihatsch W, Moreno LA, Puntis J, Shamir R, Szajewska H, Turck D. Supplementation of N-3 LCPUFA to the diet of children older than 2 years: a commentary by the ESPGHAN committee on nutrition. J Pediatr Gastroenterol Nutr. 2011;53:2–10.
De Cosmi V, Mazzocchi A, D’Oria V, Re A, Spolidoro GCI, Milani GP, Berti C, Scaglioni S, Giavoli C, Bergamaschi S. Effect of vitamin D and docosahexaenoic acid co-supplementation on vitamin D status, body composition, and metabolic markers in obese children: a randomized, double blind, controlled study. Nutrients. 2022;14:1397.
PubMed PubMed Central Google Scholar
Seif ER, Hamam MA, El-Shafiey RMG, Attia GF, El-Sawy DM. Effect of Omega-3 polyunsaturated fatty acids combined with dietary intervention on childhood obesity and insulin resistance. J Adv Med Med Res. 2023;35:149–62.
Pedersen MH, Mølgaard C, Hellgren LI, Lauritzen L. Effects of fish oil supplementation on markers of the metabolic syndrome. J Pediatr. 2010;157:395–400. e391.
Wu S, Zhu C, Wang Z, Wang S, Yuan P, Song T, Hou X, Lei Z. Effects of fish oil supplementation on cardiometabolic risk factors in overweight or obese children and adolescents: a meta-analysis of randomized controlled trials. Front Pead. 2021;9:604469.
Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ. 2021;372:n160.
PubMed PubMed Central Google Scholar
Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng HY, Corbett MS, Eldridge SM, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898.
Guyatt GH, Oxman AD, Kunz R, Brozek J, Alonso-Coello P, Rind D, Devereaux PJ, Montori VM, Freyschuss B, Vist G, et al. GRADE guidelines 6. Rating the quality of evidence–imprecision. J Clin Epidemiol. 2011;64:1283–93.
Barde MP, Barde PJ. What to use to express the variability of data: standard deviation or standard error of mean? Perspect Clin Res. 2012;3:113–6.
PubMed PubMed Central Google Scholar
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539–58.
Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088–101.
Aref M, Movahedi A, Heidari-Beni M, Kelishadi R. Effects of shrimp oil on cardio-metabolic risk factors in children and adolescents. Int J Vitam Nutr Res. 2023;93:490–7.
Dangardt F, Osika W, Chen Y, Nilsson U, Gan LM, Gronowitz E, Strandvik B, Friberg P. Omega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescents. Atherosclerosis. 2010;212:580–5.
Huang F, Del-Río-Navarro BE, Leija-Martinez J, Torres-Alcantara S, Ruiz-Bedolla E, Hernández-Cadena L, Barraza-Villarreal A, Romero-Nava R, Sanchéz-Muñoz F, Villafaña S, et al. Effect of omega-3 fatty acids supplementation combined with lifestyle intervention on adipokines and biomarkers of endothelial dysfunction in obese adolescents with hypertriglyceridemia. J Nutr Biochem. 2019;64:162–9.
Sidiartha BE, Miranda-Lora AL, Huang F, Hall-Mondragon MS, Leija-Martínez JJ. Effect of supplementation with omega-3 fatty acids on hypertriglyceridemia in pediatric patients with obesity. J Pediatr Endocrinol Metab. 2019;32:811–9.
Pedersen IGL, Bakta IM, Wiryana IM, Sutirtayasa IWP, Sjarif DR. Eicosapentaenoic acid and docosahexaenoic acid in fish oil capsule supplementation in obese children decreases serum interleukin-6 and Hepcidin and improves iron status. Bali Med J. 2017;6:97–101.
de Ferranti SD, Milliren CE, Denhoff ER, Steltz SK, Selamet Tierney ES, Feldman HA, Osganian SK. Using high-dose omega-3 fatty acid supplements to lower triglyceride levels in 10- to 19-year-olds. Clin Pediatr (Phila). 2014;53:428–38.
Sidiartha I, Vedaswari PD, Suryawan I. Fish oil capsule supplementation in children with obesity reduced c-reactive protein and improved blood pressure. Malaysian J Nutr 2020;26.
Pedersen MH, Mølgaard C, Hellgren LI, Lauritzen L. Effects of fish oil supplementation on markers of the metabolic syndrome. J Pediatr. 2010;157:395–400. 400.e391.
Bender N, Portmann M, Heg Z, Hofmann K, Zwahlen M, Egger M. Fish or n3-PUFA intake and body composition: a systematic review and meta‐analysis. Obes Rev. 2014;15:657–65.
Burrows T, Collins C, Garg M. Omega-3 index, obesity and insulin resistance in children. Int J Pediatr Obes. 2011;6:e532–539.
Mejía-Barradas CM, Del-Río-Navarro BE, Domínguez-López A, Campos-Rodríguez R, Martínez-Godínez Md-l-Á, Rojas-Hernández S, Lara-Padilla E, Abarca-Rojano E, Miliar-García Á. The consumption of n-3 polyunsaturated fatty acids differentially modulates gene expression of peroxisome proliferator-activated receptor alpha and gamma and hypoxia-inducible factor 1 alpha in subcutaneous adipose tissue of obese adolescents. Endocrine. 2014;45:98–105.
Buckley JD, Howe PR. Long-chain omega-3 polyunsaturated fatty acids May be beneficial for reducing obesity—a review. Nutrients. 2010;2:1212–30.
CAS PubMed PubMed Central Google Scholar
Vega RB, Huss JM, Kelly DP. The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Molecular and cellular biology. 2000.
Eberlé D, Hegarty B, Bossard P, Ferré P, Foufelle F. SREBP transcription factors: master regulators of lipid homeostasis. Biochimie. 2004;86:839–48.
Mori TA. Omega-3 fatty acids and cardiovascular disease: epidemiology and effects on cardiometabolic risk factors. Food Funct. 2014;5:2004–19.
Mori TA. Dietary n-3 PUFA and CVD: a review of the evidence. Proc Nutr Soc. 2014;73:57–64.
Asbaghi O, Saboori S, Falahi E, Salehpour S, Rad EY, Abdollahpour F, Ojani Z. The effect of omega-3 fatty acids and vitamin E co-supplementation on glycemic profile: a systematic review and meta-analysis of randomized controlled trials. Obes Med. 2020;17:100180.
Westphal C, Konkel A, Schunck W-H. CYP-eicosanoids—a new link between omega-3 fatty acids and cardiac disease? Prostaglandins Other Lipid Mediat. 2011;96:99–108.
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