Risk Factors for Postoperative Dysphagia in Patients with Oral Cavity and Oropharyngeal Cancer: A Systematic Review and Meta-analysis

Conway DI, Purkayastha M, Chestnutt IG. The changing epidemiology of oral cancer: definitions, trends, and risk factors. Br Dent J. 2018;225(9):867–73. https://doi.org/10.1038/sj.bdj.2018.922.

Article  CAS  PubMed  Google Scholar 

Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. https://doi.org/10.3322/caac.21660.

Article  CAS  PubMed  Google Scholar 

Caudell JJ, Gillison ML, Maghami E, et al. NCCN Guidelines® insights: head and neck cancers, version 1. J Natl Compr Canc Netw. 2022;20(3):224–34. https://doi.org/10.6004/jnccn.2022.0016.

Article  PubMed  Google Scholar 

Matsuda Y, Okui T, Karino M, et al. Postoperative oral dysfunction following oral cancer resection and reconstruction: a preliminary cross-sectional study. Oral Oncol. 2021;121:105468. https://doi.org/10.1016/j.oraloncology.2021.105468.

Article  PubMed  Google Scholar 

Hurtte E, Young J, Gyawali CP. Dysphagia Prim Care. 2023;50(3):325–38. https://doi.org/10.1016/j.pop.2023.03.001.

Article  PubMed  Google Scholar 

Speyer R, Cordier R, Farneti D, et al. White paper by the European society for swallowing disorders: screening and non-instrumental assessment for dysphagia in adults. Dysphagia. 2022;37(2):333–49. https://doi.org/10.1007/s00455-021-10283-7.

Article  PubMed  Google Scholar 

Hutcheson KA, Nurgalieva Z, Zhao H, et al. Two-year prevalence of dysphagia and related outcomes in head and neck cancer survivors: an updated SEER-medicare analysis. Head Neck. 2019;41(2):479–87. https://doi.org/10.1002/hed.25412.

Article  PubMed  Google Scholar 

Tsai YT, Lai CH, Huang TH, et al. Association of malnutrition with postoperative complication risk after curative surgery for oral cancer: observational study. Med (Baltim). 2020;99(52):e23860. https://doi.org/10.1097/MD.0000000000023860.

Article  CAS  Google Scholar 

Bozec A, Majoufre C, De Boutray M, et al. Oral and oropharyngeal cancer surgery with free-flap reconstruction in the elderly: factors associated with long-term quality of life, patient needs and concerns. A GETTEC cross-sectional study. Surg Oncol. 2020;35:81–8. https://doi.org/10.1016/j.suronc.2020.08.014.

Article  PubMed  Google Scholar 

Cristofaro MG, Barca I, Ferragina F, et al. The health risks of dysphagia for patients with head and neck cancer: a multicentre prospective observational study. J Transl Med. 2021;19(1):472. https://doi.org/10.1186/s12967-021-03144-2.

Article  PubMed  PubMed Central  Google Scholar 

Klingelhöffer C, Obst A, Ettl T, et al. Severe postoperative dysphagia as an early predictor for decreased overall survival in patients with oral cancer. J Craniomaxillofac Surg. 2019;47(9):1363–9. https://doi.org/10.1016/j.jcms.2019.06.011.

Article  PubMed  Google Scholar 

Ferro A, Basyuni S, Bosley R, et al. A predictive model for swallowing dysfunction after oral cancer resection. Br J Oral Maxillofac Surg. 2021;59(9):1043–9. https://doi.org/10.1016/j.bjoms.2021.01.007.

Article  CAS  PubMed  Google Scholar 

Gross JH, Townsend M, Hong HY, et al. Predictors of swallow function after transoral surgery for locally advanced oropharyngeal cancer. Laryngoscope. 2020;130(1):94–100. https://doi.org/10.1002/lary.27856.

Article  PubMed  Google Scholar 

Ohkoshi A, Ogawa T, Nakanome A, et al. Predictors of chewing and swallowing disorders after surgery for locally advanced oral cancer with free flap reconstruction: a prospective, observational study. Surg Oncol. 2018;27(3):490–4. https://doi.org/10.1016/j.suronc.2018.05.029.

Article  PubMed  Google Scholar 

Yamauchi T, Edahiro A, Watanabe Y, et al. Risk factors for postoperative dysphagia in oral cancer. Bull Tokyo Dent Coll. 2012;53(2):67–74. https://doi.org/10.2209/tdcpublication.53.67.

Article  PubMed  Google Scholar 

Miyamoto S, Sakuraba M, Nagamatsu S, et al. Risk factors for gastric-tube dependence following tongue reconstruction. Ann Surg Oncol. 2012;19(7):2320–6. https://doi.org/10.1245/s10434-012-2298-2.

Article  PubMed  Google Scholar 

Jiang N, Zhang LJ, Li LY, et al. Risk factors for late dysphagia after (chemo)radiotherapy for head and neck cancer: a systematic methodological review. Head Neck. 2016;38(5):792–800. https://doi.org/10.1002/hed.23963.

Article  PubMed  Google Scholar 

Iruthayarajah J, McIntyre A, Mirkowski M, et al. Risk factors for dysphagia after a spinal cord injury: a systematic review and meta-analysis. Spinal Cord. 2018;56(12):1116–23. https://doi.org/10.1038/s41393-018-0170-3.

Article  CAS  PubMed  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Int J Surg. 2021;88:105906. https://doi.org/10.1136/bmj.n71.

Article  PubMed  Google Scholar 

Zeng XT, Liu H, Chen X, et al. The fourth of meta-analysis series: quality assessment tools for observational studies. Chin J Evidence-Based Cardiovasc Med. 2012;4(04):297–9.

Google Scholar 

Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25(9):603–5. https://doi.org/10.1007/s10654-010-9491-z.

Article  PubMed  Google Scholar 

Pauloski BR, Rademaker AW, Logemann JA, et al. Surgical variables affecting swallowing in patients treated for oral/oropharyngeal cancer. Head Neck. 2004;26(7):625–36. https://doi.org/10.1002/hed.20013.

Article  PubMed  Google Scholar 

Khariwala SS, Vivek PP, Lorenz RR, et al. Swallowing outcomes after microvascular head and neck reconstruction: a prospective review of 191 cases. Laryngoscope. 2007;117(8):1359–63. https://doi.org/10.1097/MLG.0b013e3180621109.

Article  PubMed  Google Scholar 

Kalavrezos N, Cotrufo S, Govender R, et al. Factors affecting swallow outcome following treatment for advanced oral and oropharyngeal malignancies. Head Neck. 2014;36(1):47–54. https://doi.org/10.1002/hed.23262.

Article  PubMed  Google Scholar 

Fujiki M, Sakuraba M, Miyamoto S, et al. Predictive factors of dysphagia after lateral and superior oropharyngeal reconstruction with free flap transfer. J Surg Oncol. 2016;113(2):240–3. https://doi.org/10.1002/jso.24105.

Article  PubMed  Google Scholar 

Huang ZS, Chen WL, Huang ZQ, et al. Dysphagia in tongue cancer patients before and Ater surgery. J Oral Maxillofac Surg. 2016;74(10):2067–72. https://doi.org/10.1016/j.joms.2016.03.031.

Article  PubMed  Google Scholar 

Worley ML, Graboyes EM, Blair J, et al. Swallowing outcomes in elderly patients following microvascular reconstruction of the head and neck. Otolaryngol Head Neck Surg. 2018;159(2):320–7. https://doi.org/10.1177/0194599818765166.

Article  PubMed  PubMed Central  Google Scholar 

Kansara S, Wang T, Koochakzadeh S, et al. Prognostic factors associated with achieving total oral diet following osteocutaneous microvascular free tissue transfer reconstruction of the oral cavity. Oral Oncol. 2019;98:1–7. https://doi.org/10.1016/j.oraloncology.2019.09.006.

Article  PubMed  PubMed Central  Google Scholar 

Hasegawa T, Yatagai N, Furukawa T, et al. The prospective evaluation and risk factors of dysphagia after surgery in patients with oral cancer. J Otolaryngol Head Neck Surg. 2021;50(1):4. https://doi.org/10.1186/s40463-020-00479-6.

Article  PubMed  PubMed Central  Google Scholar 

Ohkoshi A, Sato N, Kurosawa K, et al. Impact of CAD/CAM mandibular reconstruction on chewing and swallowing function after surgery for locally advanced oral cancer: a retrospective study of 50 cases. Auris Nasus Larynx. 2021;48(5):1007–12. https://doi.org/10.1016/j.anl.2021.03.014.

Article  PubMed  Google Scholar 

Nakayama Y, Yamakawa N, Ueyama Y, et al. Examination of suprahyoid muscle resection and other factors affecting swallowing function in patients with advanced oral cancer after surgical resection and reconstruction. J Craniofac Surg. 2022;33(8):e840–4. https://doi.org/10.1097/SCS.0000000000008770.

Article  PubMed  PubMed Central 

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