Effect of TSH on aromatase expression of ovarian granulosa cells in obese mice

Jebeile H, Kelly AS, O’Malley G, Baur LA (2022) Obesity in children and adolescents: epidemiology, causes, assessment, and management. Lancet Diabetes Endocrinol 10:351–365. https://doi.org/10.1016/S2213-8587(22)00047-X

Article  CAS  PubMed  PubMed Central  Google Scholar 

Reinehr T, Roth CL (2019) Is there a causal relationship between obesity and puberty? Lancet Child Adolesc Health 3(1):44–54. https://doi.org/10.1016/S2352-4642(18)30306-7

Article  PubMed  Google Scholar 

Busch AS, Højgaard B, Hagen CP, Teilmann G (2020) Obesity Is Associated with Earlier Pubertal Onset in Boys. J Clin Endocrinol Metab 105:dgz222. https://doi.org/10.1210/clinem/dgz222

Article  PubMed  Google Scholar 

Brix N, Ernst A, Lauridsen LLB, Parner ET, Arah OA, Olsen J, Henriksen TB, Ramlau-Hansena CH (2020) Childhood overweight and obesity and timing of puberty in boys and girls: cohort and sibling-matched analyses. Int J Epidemiol 49:834–844. https://doi.org/10.1093/ije/dyaa056

Article  PubMed  PubMed Central  Google Scholar 

Takle ZJ, Legesse TG (2017) The effect of leptin on the hypothalamic-pituitary gonadal axis and puberty. Int J Heal Sci Res 7:332–344

Google Scholar 

Yuxin L, Chen L, Xiaoxia L, Yue L, Junjie L, Youzhu L, Huiliang Z, Qicai L (2021) Research progress on the relationship between obesity-inflammation-aromatase axis and male infertility. Oxid Med Cell Longev 2021:6612796. https://doi.org/10.1155/2021/6612796

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu T, Huang Y, Lin H (2021) Estrogen disorders: Interpreting the abnormal regulation of aromatase in granulosa cells (Review). Int J Mol Med 47:73. https://doi.org/10.3892/ijmm.2021.4906

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stocco C (2008) Aromatase expression in the ovary: hormonal and molecular regulation. Steroids 73:473–487. https://doi.org/10.1016/j.steroids.2008.01.017

Article  CAS  PubMed  PubMed Central  Google Scholar 

Crocker MK, Stern EA, Sedaka NM, Shomaker LB, Brady SM, Ali AH, Shawker TH, Hubbard VS, Yanovski JA (2014) Sexual dimorphisms in the associations of BMI and body fat with indices of pubertal development in girls and boys. J Clin Endocrinol Metab 99:E1519-1529. https://doi.org/10.1210/jc.2014-1384

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sanyal D, Raychaudhuri M (2016) Hypothyroidism and obesity: An intriguing link. Indian J Endocrinol Metab 20:554–557. https://doi.org/10.4103/2230-8210.183454

Article  CAS  PubMed  PubMed Central  Google Scholar 

An YM, Moon SJ, Kim SK, Suh YJ, Lee JE (2018) Thyroid function in obese Korean children and adolescents: Korea National Health and Nutrition Examination Survey 2013–2015. Ann Pediatr Endocrinol Metab 23:141–147. https://doi.org/10.6065/apem.2018.23.3.141

Article  PubMed  PubMed Central  Google Scholar 

Patel R, Dave C, Mehta S, Mendpara H, Shukla R, Bajpai A (2021) Metabolic Impact of Subclinical Hypothyroidism in Obese Children and Adolescents. Indian J Pediatr 88:437–440. https://doi.org/10.1007/s12098-020-03463-0

Article  PubMed  Google Scholar 

Jung G, Oh SB, Lee WY, Kim HR, Nam HK, Kim JH, Rhie YJ, Lee KH (2019) Thyroid function in girls with central precocious puberty. Ann Pediatr Endocrinol Metab 24:124–128. https://doi.org/10.6065/apem.2019.24.2.124

Article  PubMed  PubMed Central  Google Scholar 

Yigit O, Sert TK, Ekinci D, Kirankaya A, Kilinc S (2023) The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. North Clin Istanb 10:48–52. https://doi.org/10.14744/nci.2021.78300

Article  PubMed  PubMed Central  Google Scholar 

Hu Y, Wang Q, Li G, Sun X, Liu C (2013) Ultrasonic morphology of uterus and ovaries in girls with pituitary hyperplasia secondary to primary hypothyroidism. Horm Metab Res 45:669–674. https://doi.org/10.1055/s-0033-1345141

Article  CAS  PubMed  Google Scholar 

Hu YY, Li GM, Hu WW, Wang Y (2014) Characteristics of girls with pituitary hyperplasia and sexual precocity secondary to primary hypothyroidism. Acta Paediatr 103:e43-48. https://doi.org/10.1111/apa.12444

Article  CAS  PubMed  Google Scholar 

Lee SJ, Moon JE, Lee GM, Cho MH, Ko CW (2020) An Alport syndrome boy with Van Wyk-Grumbach syndrome induced by prolonged untreated congenital hypothyroidism. Ann Pediatr Endocrinol Metab 25:132–136. https://doi.org/10.6065/apem.1938074.037

Article  PubMed  PubMed Central  Google Scholar 

Dhole B, Gupta S, Shekhar S, Kumar A (2020) A novel antigonadotropic role of thyroid stimulating hormone on leydig cell-derived mouse leydig tumor cells-1 line. Ann Natl Acad Med Sci 56:30–37. https://doi.org/10.1055/s-0040-1709091

Article  PubMed  PubMed Central  Google Scholar 

Yuan Z, Shen X, Yan H, Jiang J, Liu B, Zhang L, Wu Y, Liu Y, Liu Q (2021) Effects of the thyroid endocrine system on gonadal sex ratios and sex-related gene expression in the pufferfish takifugu rubripes. Front Endocrinol (Lausanne) 12:674954. https://doi.org/10.3389/fendo.2021.674954

Article  PubMed  Google Scholar 

Liu Y, Yu T, Li X, Pan D, Lai X, Chen Y, Wang X, Yu X, Fu S, Huang S, Lin C, Liu S (2021) Prevalence of precocious puberty among Chinese children: a school population-based study. Endocrine 72:573–581. https://doi.org/10.1007/s12020-021-02630-3

Article  CAS  PubMed  Google Scholar 

Bohlen TM, Silveira MA, Zampieri TT, Frazão R, Donato J Jr (2016) Fatness rather than leptin sensitivity determines the timing of puberty in female mice. Mol Cell Endocrinol 423:11–21. https://doi.org/10.1016/j.mce.2015.12.022

Article  CAS  PubMed  Google Scholar 

Sanchez-Garrido MA, Tena-Sempere M (2013) Metabolic control of puberty: roles of leptin and kisspeptins. Horm Behav 64:187–194. https://doi.org/10.1016/j.yhbeh.2013.01.014

Article  CAS  PubMed  Google Scholar 

Elias CF (2012) Leptin action in pubertal development: recent advances and unanswered questions. Trends Endocrinol Metab 23:9–15. https://doi.org/10.1016/j.tem.2011.09.002

Article  CAS  PubMed  Google Scholar 

Ahmed ML, Ong KK, Dunger DB (2009) Childhood obesity and the timing of puberty. Trends Endocrinol Metab 20:237–242. https://doi.org/10.1016/j.tem.2009.02.004

Article  CAS  PubMed  Google Scholar 

Goldsammler M, Merhi Z, Buyuk E (2018) Role of hormonal and inflammatory alterations in obesity-related reproductive dysfunction at the level of the hypothalamic-pituitary-ovarian axis. Reprod Biol Endocrinol 16:45. https://doi.org/10.1186/s12958-018-0366-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Thaler JP, Schwartz MW (2010) Minireview: inflammation and obesity pathogenesis: the hypothalamus heats up. Endocrinology 151:4109–4115. https://doi.org/10.1210/en.2010-0336

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang A, Reinehr T, Roth CL (2020) Connections between obesity and puberty: invited by Manuel Tena-Sempere, Cordoba. Curr Opin Endocr Metab Res 14:160–168. https://doi.org/10.1016/j.coemr.2020.08.004

Article  PubMed  PubMed Central  Google Scholar 

Cleary MP, Grossmann ME (2009) Minireview: obesity and breast cancer: the estrogen connection. Endocrinology 150:2537–2542. https://doi.org/10.1210/en.2009-0070

Article  CAS 

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