Jebeile H, Kelly AS, O’Malley G, Baur LA (2022) Obesity in children and adolescents: epidemiology, causes, assessment, and management. Lancet Diabetes Endocrinol 10:351–365. https://doi.org/10.1016/S2213-8587(22)00047-X
Article CAS PubMed PubMed Central Google Scholar
Reinehr T, Roth CL (2019) Is there a causal relationship between obesity and puberty? Lancet Child Adolesc Health 3(1):44–54. https://doi.org/10.1016/S2352-4642(18)30306-7
Busch AS, Højgaard B, Hagen CP, Teilmann G (2020) Obesity Is Associated with Earlier Pubertal Onset in Boys. J Clin Endocrinol Metab 105:dgz222. https://doi.org/10.1210/clinem/dgz222
Brix N, Ernst A, Lauridsen LLB, Parner ET, Arah OA, Olsen J, Henriksen TB, Ramlau-Hansena CH (2020) Childhood overweight and obesity and timing of puberty in boys and girls: cohort and sibling-matched analyses. Int J Epidemiol 49:834–844. https://doi.org/10.1093/ije/dyaa056
Article PubMed PubMed Central Google Scholar
Takle ZJ, Legesse TG (2017) The effect of leptin on the hypothalamic-pituitary gonadal axis and puberty. Int J Heal Sci Res 7:332–344
Yuxin L, Chen L, Xiaoxia L, Yue L, Junjie L, Youzhu L, Huiliang Z, Qicai L (2021) Research progress on the relationship between obesity-inflammation-aromatase axis and male infertility. Oxid Med Cell Longev 2021:6612796. https://doi.org/10.1155/2021/6612796
Article CAS PubMed PubMed Central Google Scholar
Liu T, Huang Y, Lin H (2021) Estrogen disorders: Interpreting the abnormal regulation of aromatase in granulosa cells (Review). Int J Mol Med 47:73. https://doi.org/10.3892/ijmm.2021.4906
Article CAS PubMed PubMed Central Google Scholar
Stocco C (2008) Aromatase expression in the ovary: hormonal and molecular regulation. Steroids 73:473–487. https://doi.org/10.1016/j.steroids.2008.01.017
Article CAS PubMed PubMed Central Google Scholar
Crocker MK, Stern EA, Sedaka NM, Shomaker LB, Brady SM, Ali AH, Shawker TH, Hubbard VS, Yanovski JA (2014) Sexual dimorphisms in the associations of BMI and body fat with indices of pubertal development in girls and boys. J Clin Endocrinol Metab 99:E1519-1529. https://doi.org/10.1210/jc.2014-1384
Article CAS PubMed PubMed Central Google Scholar
Sanyal D, Raychaudhuri M (2016) Hypothyroidism and obesity: An intriguing link. Indian J Endocrinol Metab 20:554–557. https://doi.org/10.4103/2230-8210.183454
Article CAS PubMed PubMed Central Google Scholar
An YM, Moon SJ, Kim SK, Suh YJ, Lee JE (2018) Thyroid function in obese Korean children and adolescents: Korea National Health and Nutrition Examination Survey 2013–2015. Ann Pediatr Endocrinol Metab 23:141–147. https://doi.org/10.6065/apem.2018.23.3.141
Article PubMed PubMed Central Google Scholar
Patel R, Dave C, Mehta S, Mendpara H, Shukla R, Bajpai A (2021) Metabolic Impact of Subclinical Hypothyroidism in Obese Children and Adolescents. Indian J Pediatr 88:437–440. https://doi.org/10.1007/s12098-020-03463-0
Jung G, Oh SB, Lee WY, Kim HR, Nam HK, Kim JH, Rhie YJ, Lee KH (2019) Thyroid function in girls with central precocious puberty. Ann Pediatr Endocrinol Metab 24:124–128. https://doi.org/10.6065/apem.2019.24.2.124
Article PubMed PubMed Central Google Scholar
Yigit O, Sert TK, Ekinci D, Kirankaya A, Kilinc S (2023) The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. North Clin Istanb 10:48–52. https://doi.org/10.14744/nci.2021.78300
Article PubMed PubMed Central Google Scholar
Hu Y, Wang Q, Li G, Sun X, Liu C (2013) Ultrasonic morphology of uterus and ovaries in girls with pituitary hyperplasia secondary to primary hypothyroidism. Horm Metab Res 45:669–674. https://doi.org/10.1055/s-0033-1345141
Article CAS PubMed Google Scholar
Hu YY, Li GM, Hu WW, Wang Y (2014) Characteristics of girls with pituitary hyperplasia and sexual precocity secondary to primary hypothyroidism. Acta Paediatr 103:e43-48. https://doi.org/10.1111/apa.12444
Article CAS PubMed Google Scholar
Lee SJ, Moon JE, Lee GM, Cho MH, Ko CW (2020) An Alport syndrome boy with Van Wyk-Grumbach syndrome induced by prolonged untreated congenital hypothyroidism. Ann Pediatr Endocrinol Metab 25:132–136. https://doi.org/10.6065/apem.1938074.037
Article PubMed PubMed Central Google Scholar
Dhole B, Gupta S, Shekhar S, Kumar A (2020) A novel antigonadotropic role of thyroid stimulating hormone on leydig cell-derived mouse leydig tumor cells-1 line. Ann Natl Acad Med Sci 56:30–37. https://doi.org/10.1055/s-0040-1709091
Article PubMed PubMed Central Google Scholar
Yuan Z, Shen X, Yan H, Jiang J, Liu B, Zhang L, Wu Y, Liu Y, Liu Q (2021) Effects of the thyroid endocrine system on gonadal sex ratios and sex-related gene expression in the pufferfish takifugu rubripes. Front Endocrinol (Lausanne) 12:674954. https://doi.org/10.3389/fendo.2021.674954
Liu Y, Yu T, Li X, Pan D, Lai X, Chen Y, Wang X, Yu X, Fu S, Huang S, Lin C, Liu S (2021) Prevalence of precocious puberty among Chinese children: a school population-based study. Endocrine 72:573–581. https://doi.org/10.1007/s12020-021-02630-3
Article CAS PubMed Google Scholar
Bohlen TM, Silveira MA, Zampieri TT, Frazão R, Donato J Jr (2016) Fatness rather than leptin sensitivity determines the timing of puberty in female mice. Mol Cell Endocrinol 423:11–21. https://doi.org/10.1016/j.mce.2015.12.022
Article CAS PubMed Google Scholar
Sanchez-Garrido MA, Tena-Sempere M (2013) Metabolic control of puberty: roles of leptin and kisspeptins. Horm Behav 64:187–194. https://doi.org/10.1016/j.yhbeh.2013.01.014
Article CAS PubMed Google Scholar
Elias CF (2012) Leptin action in pubertal development: recent advances and unanswered questions. Trends Endocrinol Metab 23:9–15. https://doi.org/10.1016/j.tem.2011.09.002
Article CAS PubMed Google Scholar
Ahmed ML, Ong KK, Dunger DB (2009) Childhood obesity and the timing of puberty. Trends Endocrinol Metab 20:237–242. https://doi.org/10.1016/j.tem.2009.02.004
Article CAS PubMed Google Scholar
Goldsammler M, Merhi Z, Buyuk E (2018) Role of hormonal and inflammatory alterations in obesity-related reproductive dysfunction at the level of the hypothalamic-pituitary-ovarian axis. Reprod Biol Endocrinol 16:45. https://doi.org/10.1186/s12958-018-0366-6
Article CAS PubMed PubMed Central Google Scholar
Thaler JP, Schwartz MW (2010) Minireview: inflammation and obesity pathogenesis: the hypothalamus heats up. Endocrinology 151:4109–4115. https://doi.org/10.1210/en.2010-0336
Article CAS PubMed PubMed Central Google Scholar
Huang A, Reinehr T, Roth CL (2020) Connections between obesity and puberty: invited by Manuel Tena-Sempere, Cordoba. Curr Opin Endocr Metab Res 14:160–168. https://doi.org/10.1016/j.coemr.2020.08.004
Article PubMed PubMed Central Google Scholar
Cleary MP, Grossmann ME (2009) Minireview: obesity and breast cancer: the estrogen connection. Endocrinology 150:2537–2542. https://doi.org/10.1210/en.2009-0070
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