Armitage GC (1999) Development of a classification system for periodontal diseases and conditions. Ann Periodontol 4:1–6. https://doi.org/10.1902/annals.1999.4.1.1

Article  CAS  PubMed  Google Scholar 

Caton JG, Armitage G, Berglundh T, Chapple ILC, Jepsen S, Kornman KS, Mealey BL, Papapanou PN, Sanz M, Tonetti MS (2018) A new classification scheme for periodontal and peri-implant diseases and conditions - Introduction and key changes from the 1999 classification. J Clin Periodontol 20:S1–S8. https://doi.org/10.1111/jcpe.12935

Article  Google Scholar 

Raza M, Abud DG, Wang J, Shariff JA (2024) Ease and practicability of the 2017 classification of periodontal diseases and conditions: a study of dental electronic health records. BMC Oral Health 24:621. https://doi.org/10.1186/s12903-024-04385-5

Article  PubMed  PubMed Central  Google Scholar 

Papapanou PN, Sanz M, Buduneli N, Dietrich T, Feres M, Fine DH, Flemmig TF, Garcia R, Giannobile WV, Graziani F (2018) Periodontitis: consensus report of workgroup 2 of the 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions. J Periodontol 89:S173–S182. https://doi.org/10.1111/jcpe.12946

Article  PubMed  Google Scholar 

Fine DH, Patil AG, Loos BG (2018) Classification and diagnosis of aggressive periodontitis. J Clin Periodontol 45:S95–S111. https://doi.org/10.1002/JPER.16-0712

Article  PubMed  Google Scholar 

Kim TJ, Littlejohn CG, Richey KH, Falsafi N, Li C, Wang T-J, Lander B, Chang Y-C (2023) A modern approach to treat molar/incisor pattern periodontitis. J Clin Med 12:6107. https://doi.org/10.3390/jcm12186107

Article  CAS  PubMed  PubMed Central  Google Scholar 

Demmer RT (2000) Papapanou PN (2010) Epidemiologic patterns of chronic and aggressive periodontitis. Periodontol 53:28–44. https://doi.org/10.1111/j.1600-0757.2009.00326.x

Article  Google Scholar 

Gupta S, Maharjan A, Dhami B, Amgain P, Katwal S, Adhikari B, Shukla A (2018) Status of tobacco smoking and diabetes with periodontal disease. JNMA 56:818–824. https://doi.org/10.31729/jnma.3610

Article  Google Scholar 

Yoshida A, Bouziane A, Erraji S, Lakhdar L, Rhissassi M, Miyazaki H, Ansai T, Iwasaki M, Ennibi O (2021) Etiology of aggressive periodontitis in individuals of African descent. Jpn Dent Sci Rev 57:20–26. https://doi.org/10.1016/j.jdsr.2020.12.001

Article  PubMed  PubMed Central  Google Scholar 

Roshna T, Nandakumar K (2012) Generalized aggressive periodontitis and its treatment options: case reports and review of the literature. Case Rep Med 2012:535321. https://doi.org/10.1155/2012/535321

Article  CAS  PubMed  PubMed Central  Google Scholar 

Di Stefano M, Polizzi A, Santonocito S, Romano A, Lombardi T, Isola G (2022) Impact of oral microbiome in periodontal health and periodontitis: a critical review on prevention and treatment. Int J Mol Sci 23:5142. https://doi.org/10.3390/ijms23095142

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garcia-Leme J, Farsky SP (1993) Hormonal control of inflammatory responses. Mediators Inflamm 2:181–198. https://doi.org/10.1155/s0962935193000250

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mascarenhas P, Gapski R, Al-Shammari K, Wang HL (2003) Influence of sex hormones on the periodontium. J Clin Periodontol 30:671–681. https://doi.org/10.1034/j.1600-051x.2003.00055.x

Article  CAS  PubMed  Google Scholar 

Silva N, Abusleme L, Bravo D, Dutzan N, Garcia-Sesnich J, Vernal R, Hernández M, Gamonal J (2015) Host response mechanisms in periodontal diseases. J Appl Oral Sci 23:329–355. https://doi.org/10.1590/1678-775720140259

Article  CAS  PubMed  PubMed Central  Google Scholar 

Becerik S, Afacan B, Oztürk V, Atmaca H, Emingil G (2011) Gingival crevicular fluid calprotectin, osteocalcin and cross-linked N-terminal telopeptid levels in health and different periodontal diseases. Dis Markers 31:343–352. https://doi.org/10.3233/dma-2011-0849

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cakmak O, Tasdemir Z, Aral CA, Dundar S, Koca HB (2016) Gingival crevicular fluid and saliva stress hormone levels in patients with chronic and aggressive periodontitis. J Clin Periodontol 43:1024–1031. https://doi.org/10.1111/jcpe.12614

Article  CAS  PubMed  Google Scholar 

Botelho J, Machado V, Mascarenhas P, Rua J, Alves R, Cavacas MA, Delgado A, João Mendes J (2018) Stress, salivary cortisol and periodontitis: a systematic review and meta-analysis of observational studies. Arch Oral Biol 96:58–65. https://doi.org/10.1016/j.archoralbio.2018.08.016

Article  CAS  PubMed  Google Scholar 

Gerin E, Buysschaert M, Lasserre JF, Leprince JG, Toma S (2023) Glycemic and insulin status in periodontitis patients using the homeostasis model assessment (HOMA): a pilot study. Oral Health Prev Dent 21:2–6. https://doi.org/10.3290/j.ohpd.b3818027

Article  PubMed  Google Scholar 

Sooriyamoorthy M, Gower DB (1989) Hormonal influences on gingival tissue: relationship to periodontal disease. J Clin Periodontol 16:201–208. https://doi.org/10.1111/j.1600-051x.1989.tb01642.x

Article  CAS  PubMed  Google Scholar 

Barnawi BM, Alrashidi NS, Albalawi AM, Alakeel NS, Hamed JT, Barashid AA, Alduraibi MS, Alhussain GS, Alghadeer JY, Alarifi NA (2023) Nutritional modulation of periodontal diseases: a narrative review of recent evidence. Cureus 15:e50200. https://doi.org/10.7759/cureus.50200

Article  PubMed  PubMed Central  Google Scholar 

Mahalakshmi A (2023) Melatonin and Periodontal Disease: A Review. Int J Appl Dent Sci 9:6. https://doi.org/10.22271/oral.2023.v9.i2b.1723

Article  Google Scholar 

Kundak K, Yarat A, Dogan B, Kuru L (2022) Effect of non-surgical periodontal therapy on salivary melatonin levels. Clin Exp Health Sci 12:1032–1039. https://doi.org/10.33808/clinexphealthsci.1053211

Article  CAS  Google Scholar 

Almughrabi OM, Marzouk KM, Hasanato RM, Shafik SS (2013) Melatonin levels in periodontal health and disease. J Periodontal Res 48:315–321. https://doi.org/10.1111/jre.12010

Article  CAS  PubMed  Google Scholar 

Ghallab NA, Hamdy E, Shaker OG (2016) Malondialdehyde, superoxide dismutase and melatonin levels in gingival crevicular fluid of aggressive and chronic periodontitis patients. Aust Dent J 61:53–61. https://doi.org/10.1111/adj.12294

Article  CAS  PubMed  Google Scholar 

Özcan E, Saygun I, Kantarcı A, Özarslantürk S, Serdar M, Özgürtaş T (2021) The effects of a novel non-invasive application of platelet-rich fibrin on periodontal clinical parameters and gingival crevicular fluid transforming growth factor-β and collagen-1 levels: A randomized, controlled, clinical study. J Periodontol 92:1252–1261. https://doi.org/10.1002/JPER.20-0713

Article  PubMed  Google Scholar 

Gürkan A, Emingil G, Cinarcik BA (2006) Gingival crevicular fluid transforming growth factor-beta1 in several forms of periodontal disease. Arch Oral Biol 51:906–912. https://doi.org/10.1016/j.archoralbio.2006.04.008

Article  CAS  PubMed  Google Scholar 

Yin L, Li X, Hou J (2022) Macrophages in periodontitis: a dynamic shift between tissue destruction and repair. Jpn Dent Sci Rev 58:336–347. https://doi.org/10.1016/j.jdsr.2022.10.002

Article  PubMed  PubMed Central  Google Scholar 

Mangiavini L, Peretti G, Canciani MN (2022) Epidermal growth factor signalling pathway in endochondral ossification: an evidence-based narrative review. Ann Med 54:37–50. https://doi.org/10.1080/07853890.2021.2015798

Article  CAS  PubMed  Google Scholar 

Wang X, Li W, Xu L, Lu R, Meng H (2020) The association of EGF rs2237051 variant, serum EGF levels and generalized aggressive periodontitis: a preliminary study. PeerJ 8:e9212. https://doi.org/10.7717/peerj.92