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Leptin affects spermatogenic function via activation of the Akt/ERK/AMPK signaling pathway
Leptin affects spermatogenic function via activation of the Akt/ERK/AMPK signaling pathway
Obesity is often associated with elevated leptin levels and leptin resistance, which can lead to impaired reproductive fun...
The clinical spectrum of adrenal ganglioneuromas extends from severe hypertension to an asymptomatic incidentaloma; two cases and mini review of literature
The clinical spectrum of adrenal ganglioneuromas extends from severe hypertension to an asymptomatic incidentaloma; two cases and mini review of literature
Herein, we present two interesting cases of adrenal ganglioneuromas (AGNs), namely, (a) a giant AGN which caused a severe ...
Hypertensive retinopathy as the first manifestation of extra-adrenal paraganglioma
Hypertensive retinopathy as the first manifestation of extra-adrenal paraganglioma
Paragangliomas are rare neuroendocrine tumors originating from paraganglionic cells in the autonomic nervous system and wh...
Interrelationship between the menstrual cycle and the phenomena associated with orthodontic tooth movement in young female patients: a systematic review
Interrelationship between the menstrual cycle and the phenomena associated with orthodontic tooth movement in young female patients: a systematic review
Alterations in the levels of female sex hormones throughout the menstrual cycle can affect bone turnover, which, in turn, ...
Exploration of the relationship between Graves’ eye disease and type 2 diabetes based on biomarkers
Exploration of the relationship between Graves’ eye disease and type 2 diabetes based on biomarkers
The development of Graves’ ophthalmopathy (GO) is silent and can be accompanied by type 2 diabetes (T2D). However, t...
Diagnosis and management of primary hyperparathyroidism: recommendations from the Bone Section of the Hellenic Endocrine Society
Diagnosis and management of primary hyperparathyroidism: recommendations from the Bone Section of the Hellenic Endocrine Society
Upon request from the Hellenic Endocrine Society, its Bone Section formed a working group to extensively review the litera...
Post-hypoglycemic nocturnal hyperglycemia in type 1 diabetes: the Somogyi hypothesis revisited
Post-hypoglycemic nocturnal hyperglycemia in type 1 diabetes: the Somogyi hypothesis revisited
The plausibility of the Somogyi phenomenon (dawn hyperglycemia after nocturnal hypoglycemia) has been questioned....
Investigating hormonal imbalances in aggressive periodontitis: a scoping review
Investigating hormonal imbalances in aggressive periodontitis: a scoping review
This study aims to consolidate the existing literature on the role of hormones in aggressive periodontitis. A systematic s...
Association of medium-chain acyl-CoA dehydrogenase with the risk of diabetic kidney disease: a mendelian randomized study
Association of medium-chain acyl-CoA dehydrogenase with the risk of diabetic kidney disease: a mendelian randomized study
Our aim is to evaluate the causal association between medium-chain acyl-CoA dehydrogenase (MCAD) and the incidence of diab...
The hidden influence of type 2 diabetes on bone mineral density across the lifespan: a Mendelian randomization study
The hidden influence of type 2 diabetes on bone mineral density across the lifespan: a Mendelian randomization study
This study investigates the causal relationship between type 2 diabetes mellitus (T2DM) and bone mineral density (BMD) acr...
Associations between visceral adipose index, lipid accumulation products, and thyroid function parameters in U.S. Adults: analysis of NHANES data
Associations between visceral adipose index, lipid accumulation products, and thyroid function parameters in U.S. Adults: analysis of NHANES data
Obesity, particularly visceral adiposity, is linked to altered thyroid function; the underlying mechanisms, however, remai...
Association between serum albumin levels and risk of deep vein thrombosis in diabetic patients: a retrospective case-control study
Association between serum albumin levels and risk of deep vein thrombosis in diabetic patients: a retrospective case-control study
This study aimed to evaluate the predictive value of serum albumin (ALB) levels for deep vein thrombosis (DVT) in diabetic...
Epigenetic effects of endogenous and exogenous glucocorticosteroids during pregnancy on the offspring: a systematic-narrative review
Epigenetic effects of endogenous and exogenous glucocorticosteroids during pregnancy on the offspring: a systematic-narrative review
Τhe epigenetic effects of glucocorticosteroids—also known as glucocorticoids—(GCs) on the human epigenome...
Distinctive hobnail subtype of papillary thyroid carcinoma: a case series and short review of literature
Distinctive hobnail subtype of papillary thyroid carcinoma: a case series and short review of literature
The hobnail subtype of papillary thyroid carcinoma (HSPTC) is a rare and aggressive subtype, comprising 1–2% of all ...
Association between thyroid function and type 2 diabetes mellitus based on the NHANES and Mendelian randomization study
Association between thyroid function and type 2 diabetes mellitus based on the NHANES and Mendelian randomization study
Many observational studies have reported an association between thyroid function and type 2 diabetes mellitus (T2DM), but ...
Cisapride for gastric emptying in diabetic patients: a meta-analysis on its efficacy and safety
Cisapride for gastric emptying in diabetic patients: a meta-analysis on its efficacy and safety
Diabetic gastroparesis is a common complication of diabetes, characterized by delayed gastric emptying, significantly impa...
Diagnosis and management of hypoparathyroidism: recommendations of the working group of the Bone Section of the Hellenic Endocrine Society
Diagnosis and management of hypoparathyroidism: recommendations of the working group of the Bone Section of the Hellenic Endocrine Society
Hypoparathyroidism (HypoPT) is a rare endocrine disorder characterized by hypocalcemia accompanied by low or inappropriate...
Effect of TSH on aromatase expression of ovarian granulosa cells in obese mice
Effect of TSH on aromatase expression of ovarian granulosa cells in obese mice
Aromatase plays an important role in ovarian development, the normal progress of the menstrual cycle, and fertility status...
Somatic USP8 alteration affects the immune landscape of corticotroph pituitary adenomas– a pilot study
Somatic USP8 alteration affects the immune landscape of corticotroph pituitary adenomas– a pilot study
Somatic mutations in ubiquitin-specific protease-8 (USP8), encoding a deubiquinating protein, are found in approximately 3...
Challenges and pitfalls in the management of endocrine toxicities from immune checkpoint inhibitors: a case presentation of synchronous thyrotoxicosis and primary adrenal insufficiency in a melanoma patient
Challenges and pitfalls in the management of endocrine toxicities from immune checkpoint inhibitors: a case presentation of synchronous thyrotoxicosis and primary adrenal insufficiency in a melanoma patient
Immune checkpoint inhibitors have revolutionized the therapeutic approach to several solid tumors, becoming the standard o...
The value of ACR, European, Korean, and ATA ultrasound risk stratification systems combined with RAS mutations for detecting thyroid carcinoma in cytologically indeterminate and suspicious for malignancy thyroid nodules
The value of ACR, European, Korean, and ATA ultrasound risk stratification systems combined with RAS mutations for detecting thyroid carcinoma in cytologically indeterminate and suspicious for malignancy thyroid nodules
The aim of this study was to evaluate the diagnostic value of four commonly utilized ultrasound (US) RSSs, namely, the Ame...
The molecular genetics of adrenal cushing
The molecular genetics of adrenal cushing
Adrenal Cushing represents 20% of cases of endogenous hypercorticism. Unilateral cortisol-producing adenoma (CPA), a benig...
Choristoma: a very rare cause of thyroid nodule. Case report and literature review
Choristoma: a very rare cause of thyroid nodule. Case report and literature review
Choristoma is a well-defined benign lesion formed by histologically normal tissue in an unusual location. Diagnosis is con...
Serum phosphate levels at diagnosis predict long-term risk for hypopituitarism in patients with acromegaly
Serum phosphate levels at diagnosis predict long-term risk for hypopituitarism in patients with acromegaly
Excess growth hormone (GH) secretion in acromegaly has a major impact on mineral balance and serum phosphate levels. Howev...
Highlighting the contribution of the Greek physician Theodoros Aretaios to the history of thyroidectomy
Highlighting the contribution of the Greek physician Theodoros Aretaios to the history of thyroidectomy
Theodoros Aretaios (1829–1893), having pursued advanced studies at home and abroad and possessing a wide range of co...
Thyroid complications after hemopoietic stem cell transplantation in children and adolescents
Thyroid complications after hemopoietic stem cell transplantation in children and adolescents
To evaluate the prevalence of thyroid dysfunction and its association with possible contributing factors related to diagno...
Performance of ACR-TIRADS in assessing thyroid nodules does not vary according to patient age
Performance of ACR-TIRADS in assessing thyroid nodules does not vary according to patient age
A few studies have evaluated the performance of the American College of Radiology Thyroid Imaging Reporting And Data Syste...
46,ΧΥ DSD in an adolescent with a novel de novo variant of the NR5A1 gene - case report and literature review
46,ΧΥ DSD in an adolescent with a novel de novo variant of the NR5A1 gene - case report and literature review
In addition to chromosomal abnormalities, several genes have been implicated as causes of disorders of sex development (DS...
Examining aldosterone plasma concentration alterations post-ACTH stimulation in healthy subjects: a systematic literature review and meta-analysis on ACTH’s role in aldosterone secretion
Examining aldosterone plasma concentration alterations post-ACTH stimulation in healthy subjects: a systematic literature review and meta-analysis on ACTH’s role in aldosterone secretion
Adrenocorticotropic hormone (ACTH), in addition to the renin–angiotensin–aldosterone axis, is a potent aldoste...
Testosterone therapy for functional hypogonadism in middle-aged and elderly males: current evidence and future perspectives
Testosterone therapy for functional hypogonadism in middle-aged and elderly males: current evidence and future perspectives
Population aging is a global phenomenon driving research focus toward preventing and managing age-related disorders. Funct...
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