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Bone Mineral Density During Treatment with The Janus Kinase Inhibitor Baricitinib in Patients with Rheumatoid Arthritis: A Monocentric Observational Study
Bone Mineral Density During Treatment with The Janus Kinase Inhibitor Baricitinib in Patients with Rheumatoid Arthritis: A Monocentric Observational Study
Rheumatoid arthritis (RA) is associated with systemic bone loss and thus an established risk factor for osteoporosis. Janu...
The Role of Heparan Sulfate in Bone Repair and Regeneration
The Role of Heparan Sulfate in Bone Repair and Regeneration
Heparan sulfate (HS) is synthesized in majority of cells in the human body and is typically released as an extension of po...
Impacts of Nonenzymatic Glycation Crosslinks in Bone Matrix on the Mechanosensitivity of Osteocyte
Impacts of Nonenzymatic Glycation Crosslinks in Bone Matrix on the Mechanosensitivity of Osteocyte
The products of nonenzymatic glycation (NEG) are a key contributor to various types of osteoporosis, as they affect both t...
Effect of Oral Semaglutide on Volumetric BMD and Bone Microarchitecture in Overweight/Obese Individuals with Type 2 Diabetes
Effect of Oral Semaglutide on Volumetric BMD and Bone Microarchitecture in Overweight/Obese Individuals with Type 2 Diabetes
Obesity, type 2 diabetes, and therapeutic weight loss are all associated with impaired bone quantity and microarchitecture...
Effectiveness of Radiotherapy in Preventing Heterotopic Ossification: A Meta-analysis of Randomized Controlled Trials Beyond Total Hip Arthroplasty
Effectiveness of Radiotherapy in Preventing Heterotopic Ossification: A Meta-analysis of Randomized Controlled Trials Beyond Total Hip Arthroplasty
Heterotopic ossification (HO) frequently occurs after procedures such as hip replacements, acetabular fractures, and elbow...
Consensus-Based Recommendations for the Diagnosis, Treatment, and Monitoring of Hypoparathyroidism: Insights from the DACH Region
Consensus-Based Recommendations for the Diagnosis, Treatment, and Monitoring of Hypoparathyroidism: Insights from the DACH Region
Hypoparathyroidism (HypoPT) is a rare endocrine disorder characterized by low parathyroid hormone (PTH) levels, hypocalcem...
Clinical, Biochemical and Radiological Features of Gene Variants in Children
Clinical, Biochemical and Radiological Features of Gene Variants in Children
Alterations in the low-density lipoprotein receptor-related protein 5 (LRP5) gene have been associated with primary osteop...
Quantitative Computed Tomography-Based Analysis of Bone Structure in the Surgical Neck of the Humerus during Aging in Men
Quantitative Computed Tomography-Based Analysis of Bone Structure in the Surgical Neck of the Humerus during Aging in Men
The changes in bone mineral density (BMD), bone structure, and bone size at the proximal humerus with aging, which can lea...
Evaluation of Low Alkaline Phosphatase Levels in Clinical Practice: Implications for Diagnosing Hypophosphatasia
Evaluation of Low Alkaline Phosphatase Levels in Clinical Practice: Implications for Diagnosing Hypophosphatasia
Persistent low serum alkaline phosphatase (ALP) levels are crucial in identifying genetic disorders such as hypophosphatas...
Effects of Peripheral Magnetic Stimulation on Bone Healing After Fractures in Mice
Effects of Peripheral Magnetic Stimulation on Bone Healing After Fractures in Mice
Bone fractures, especially in the elderly, are increasing, posing challenges to healthcare systems. Traditional treatment ...
Moderate-to-High 5-Year Cumulative Disease Activity and Lower Bone Mineral Density at the Proximal Femur are Major Predictors of Fragility Fractures in Women with Longstanding Rheumatoid Arthritis: An Observational Cohort Study
Moderate-to-High 5-Year Cumulative Disease Activity and Lower Bone Mineral Density at the Proximal Femur are Major Predictors of Fragility Fractures in Women with Longstanding Rheumatoid Arthritis: An Observational Cohort Study
Rheumatoid arthritis (RA) has a higher risk of fractures that is often neglected. We determined the prevalence and risk fa...
Multiscale Analysis Reveals Altered Characteristics in Femur and Mandible of Mice on a High Phosphate Diet
Multiscale Analysis Reveals Altered Characteristics in Femur and Mandible of Mice on a High Phosphate Diet
Excessive phosphate used as flavor enhancers and preservatives in processed foods can exacerbate cardiovascular and kidney...
Early Postmenopausal Fragility Fractures and Elevated IgE: Two Cases Suggesting Hyper-IgE Syndrome and a Novel Adverse Reaction to Romosozumab
Early Postmenopausal Fragility Fractures and Elevated IgE: Two Cases Suggesting Hyper-IgE Syndrome and a Novel Adverse Reaction to Romosozumab
Severe, treatment-refractory or early-onset osteoporosis should prompt evaluation for secondary causes. Hyper-IgE syndrome...
Bone Density, Microarchitecture, and Geometry Assessment in Patients with Pachydermoperiostosis Using Second-Generation High-Resolution Peripheral Quantitative Computed Tomography: A Case–Control Study
Bone Density, Microarchitecture, and Geometry Assessment in Patients with Pachydermoperiostosis Using Second-Generation High-Resolution Peripheral Quantitative Computed Tomography: A Case–Control Study
Pachydermoperiostosis (PDP) is a rare genetic disorder manifesting with periostosis, clubbing, and thickened skin. The imp...
Treatment with the DSM 32947 Increases Bone Mineral Density in Female Mice
Treatment with the DSM 32947 Increases Bone Mineral Density in Female Mice
Previous studies have shown that the gut microbiota regulates bone mass and that certain strains of Bifidobacterium longum...
Clinical Characteristics and Management of Rare Metabolic Bone Diseases: An Audit of the Rare Metabolic Bone Disease Registry of India
Clinical Characteristics and Management of Rare Metabolic Bone Diseases: An Audit of the Rare Metabolic Bone Disease Registry of India
Rare diseases, defined by the 2002 Rare Disease Act, affect fewer than 5 in 10,000 individuals. Rare metabolic bone diseas...
X-Linked Hypophosphatemia: Role of Fibroblast Growth Factor 23 on Human Skeletal Muscle-Derived Cells
X-Linked Hypophosphatemia: Role of Fibroblast Growth Factor 23 on Human Skeletal Muscle-Derived Cells
X-linked hypophosphatemia (XLH) is a rare and progressive disease, due to inactivating mutations in the phosphate-regulati...
Multi-trait Genome-Wide Analysis Identified 20 Novel Loci for Sarcopenia-Related Traits in UK Biobank
Multi-trait Genome-Wide Analysis Identified 20 Novel Loci for Sarcopenia-Related Traits in UK Biobank
This study aims to identify novel loci associated with sarcopenia-related traits in UK Biobank (UKB) through multi-trait g...
Base of Skull & Spinal Canal Narrowing in an Adolescent with Autosomal Recessive Hypophosphatemic Rickets Type 2
Base of Skull & Spinal Canal Narrowing in an Adolescent with Autosomal Recessive Hypophosphatemic Rickets Type 2
Autosomal recessive hypophosphatemic rickets type 2 (ARHR2) is an uncommon hereditary form of rickets characterised by chr...
The Management of Bone Defects in Rett Syndrome
The Management of Bone Defects in Rett Syndrome
Rett syndrome (RS) is a rare neurodevelopmental disorder primarily caused by mutations in the X-linked methyl-CpG binding ...
Conflating the Operational Definition of Osteoporosis with Intervention Thresholds
Conflating the Operational Definition of Osteoporosis with Intervention Thresholds
Wáng YXJ, Griffith JF, Blake GM, Diacinti D, Xiao BH, Yu W, Su Y, Jiang Y, Guglielmi G, Guermazi A, Kwok TCY (2024) Revisi...
Treatment Advances in Tumor-Induced Osteomalacia
Treatment Advances in Tumor-Induced Osteomalacia
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by hypersecretion of fibroblast growth factor 23...
Effects of Pregnancy and Lactation on Bone Microstructure and Material Properties in a Rat Model of Bariatric Surgery
Effects of Pregnancy and Lactation on Bone Microstructure and Material Properties in a Rat Model of Bariatric Surgery
Obesity is a major public health issue worldwide. Despite various approaches to weight loss, the most effective technique ...
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls
Pentosidine (PEN), a surrogate marker of advanced glycation end-product formation, reflects increased non-enzymatic cross-...
Adipose-Derived Stromal Cell Conditioned Medium on Bone Remodeling: Insights from a 3D Osteoblast–Osteoclast Co-Culture Model
Adipose-Derived Stromal Cell Conditioned Medium on Bone Remodeling: Insights from a 3D Osteoblast–Osteoclast Co-Culture Model
This study describes the potential of the conditioned medium (CM) from adipose-derived mesenchymal stromal cells (ASCs) to...
Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Effect of Eight Months of Swimming on Bone Quality of Different Anatomical Regions: A Study on Wistar Rat Models
Swimming is a popular sport with several health benefits, but its effects on bone quality are controversial possibly due t...
Tibial Skeletal Adaptations in Male and Female Marine Corps Officer Candidates Undergoing 10 Weeks of Military Training
Tibial Skeletal Adaptations in Male and Female Marine Corps Officer Candidates Undergoing 10 Weeks of Military Training
Military training improves tibial density, structure, and estimated strength; however, men and women may adapt differently...
The Multifactorial Relationship Between Bone Tissue Water and Stiffness at the Proximal Femur
The Multifactorial Relationship Between Bone Tissue Water and Stiffness at the Proximal Femur
Bone mechanical function is determined by multiple factors, some of which are still being elucidated. Here, we present a m...
18F-Sodium Fluoride PET/CT as a Tool to Assess Enthesopathies in X-Linked Hypophosphatemia
18F-Sodium Fluoride PET/CT as a Tool to Assess Enthesopathies in X-Linked Hypophosphatemia
X-linked hypophosphatemia (XLH) is a rare metabolic disorder characterized by elevated FGF23 and chronic hypophosphatemia,...
Unusual Association of Partial Fanconi Syndrome and Tumor-Induced Osteomalacia Revealed by Multiple Vertebral Fractures
Unusual Association of Partial Fanconi Syndrome and Tumor-Induced Osteomalacia Revealed by Multiple Vertebral Fractures
Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic syndrome caused by a mesenchymal tumor secreting a phos...
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