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SCI Abstract
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Genetics of urinary bladder paragangliomas: a multi-center study of a Chinese cohort
Pheochromocytomas and paragangliomas (PPGLs) exhibit the highest degree of heritability among all human tumors, yet the ge...
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The immune mechanism of the mTOR/ACC1/CPT1A fatty acid oxidation signaling pathway in Hashimoto’s thyroiditis
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Aggressive variants of papillary thyroid carcinoma: characteristics, influencing factors, and effectiveness of radioiodine therapy
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Metabolic, genetic and immunological features of relatives of type 1 diabetes patients with elevated insulin resistance
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Was the painter’s model for Hercules an acromegalic giant?
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Deciphering 18F-DOPA uptake in SDH-related head and neck paragangliomas: a radiomics approach
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PCOS - the many faces of a disorder in women and men
Polycystic ovary syndrome (PCOS) is a very common endocrine, metabolic and reproductive disorder. The underlying pathophys...
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An integrated view of the pathophysiological crosstalk between adipose tissue, bone and cardiovascular system in men and women
Obesity, bone-related and cardiovascular diseases (CVD) are among the leading global health concerns. Growing evi...
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Performance of computer scientists in the assessment of thyroid nodules using TIRADS lexicons
Ultrasound (US) evaluation is recognized as pivotal in assessing the risk of malignancy (RoM) of thyroid nodules (TNs). Re...
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Insights into pubertal development: a narrative review on the role of epigenetics
Puberty is a key phase of growth and development, characterized by psychophysical transformations. It is driven by a combi...
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Diagnostic delay, older age, and hormonal levels at diagnosis affect disease burden and mortality in acromegaly
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Influence of androgen receptor on bone health in transgender adults: insights from the COMET study
Previous studies show that transgender and gender-diverse (TGD) individuals, especially those assigned male at birth (AMAB...
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Aetiology, diagnosis and treatment of thalassemia-associated osteoporosis of the adult
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Emperor Leo I “the Thracian”: a possible case of Graves’ orbitopathy
Representation of exophthalmos in ancient artworks is reported by several authors. In the present paper we analyze a sculp...
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SP1 activates AKT3 to facilitate the development of diabetic nephropathy
Diabetic nephropathy (DN) is a severe complication of diabetes mellitus and has the complex pathogenesis. The previous stu...
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Long noncoding RNA FAM111A-DT promotes aggressiveness of papillary thyroid cancer via activating NF-κB signaling
Long noncoding RNAs (lncRNAs) play crucial regulatory roles in the tumorigenesis and progression of various cancers. Howev...
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Rachel score: a nomogram model for predicting the prognosis of lung neuroendocrine tumors
Lung NET, classified in typical carcinoids (TC) and atypical carcinoids (AC), are highly heterogeneous in their biology an...
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Sculptures with goiter in the Ossuccio Sacred Mount: when pathognomonic signs have a specific moral significance
Conflict of interest The authors declare no competing inter...
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Mouse model of Graves’ orbitopathy induced by the immunization with TSHR A and IGF-1R α subunit gene
The study aimed to establish a mouse model of Graves’ disease (GD) with Graves’ orbitopathy (GO; GD +...
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Assessment of aortomesenteric distance and mesenteric and retroperitoneal adipose tissue thickness in genetic forms of lipodystrophy
Lipodystrophy is a rare disease characterized by the loss of adipose tissue. Visceral adipose tissue loss in certain forms...
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Evaluation of pituitary function and metabolic parameters in patients with traumatic maxillofacial fractures
This study was designed to assess the pituitary functions of patients with traumatic maxillofacial fractures and compare t...
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Glucocorticoid treatment and adrenal suppression in children: current view and open issues
Glucocorticoids (GCs) are commonly used for several acute and chronic pediatric diseases. However, chronic treatment may r...
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The need for the GREAT+ score to predict relapse in Graves’ disease: a questionnaire among patients and internal medicine specialists
Graves’ disease (GD) is an auto-immune cause of hyperthyroidism. First-line treatment often consists of a 12–1...
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Sodium-glucose cotransporter 2 inhibitors and cancer: a systematic review and meta-analysis
The effect of sodium–glucose cotransporter 2 (SGLT2) inhibitors on cancer has yet to be fully elucidated. This syste...
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Development of a diagnostic model for pre-washout screening of primary aldosteronism
Primary aldosteronism (PA) diagnosis is affected by antihypertensive drugs that are commonly taken by patients with suspec...
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Molecular mechanisms underlying the effects of hypo- and hyper-prolactinemia on spermatogenesis and fertility in male rats
Hypo- and hyper-prolactinemia have deleterious effects on male reproduction, yet there is a dearth of information regardin...
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Decreased trabecular bone score in patients affected by Fabry disease
Fabry disease (FD) is an inherited X-linked lysosomal storage disease characterized by increased risk of osteoporosis and ...
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FT4 is a novel indicator for risk assessment of severe hypocalcemia following parathyroidectomy
To analyze the risk factors associated with the development of severe hypocalcemia (SH) in patients who have undergone par...
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Accelerated biological aging, mediating amino acids, and risk of incident type 2 diabetes: a prospective cohort study
Aging plays an important role in type 2 diabetes mellitus (T2DM). But the association between accelerated biological age a...
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Spliceosome component TCERG1 regulates the aggressiveness of somatotroph adenoma
We aimed to identify differentially expressed spliceosome components in growth hormone (GH)-secreting pituitary tumors and...
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