Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, et al. 2023 ESC Guidelines for the management of acute coronary syndromes: Developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC). Eur Heart J. 2023;44(38):3720–826.

Article  CAS  PubMed  Google Scholar 

Ahmadi A, Argulian E, Leipsic J, Newby DE, Narula J. From subclinical atherosclerosis to plaque progression and acute coronary events: JACC state-of-the-art review. J Am Coll Cardiol. 2019;74(12):1608–17.

Article  PubMed  Google Scholar 

Matter MA, Paneni F, Libby P, Frantz S, Stähli BE, Templin C, et al. Inflammation in acute myocardial infarction: the good, the bad and the ugly. Eur Heart J. 2024;45(2):89–103.

Article  CAS  PubMed  Google Scholar 

Stark K, Massberg S. Interplay between inflammation and thrombosis in cardiovascular pathology. Nat Rev Cardiol septiembre de. 2021;18(9):666–82.

Article  Google Scholar 

Libby P. Inflammation during the life cycle of the atherosclerotic plaque. Cardiovasc Res. 2021;117(13):2525–36.

CAS  PubMed  PubMed Central  Google Scholar 

Soehnlein O. Multiple roles for neutrophils in atherosclerosis. Circ Res. 2012;110(6):875–88.

Article  CAS  PubMed  Google Scholar 

Nahrendorf M, Swirski FK. Neutrophil-macrophage communication in inflammation and atherosclerosis. Science. 2015;349(6245):237–8.

Article  CAS  PubMed  Google Scholar 

Döring Y, Soehnlein O, Weber C. Neutrophil extracellular traps in atherosclerosis and atherothrombosis. Circ Res. 2017;120(4):736–43.

Article  PubMed  Google Scholar 

Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, et al. Neutrophil extracellular traps kill bacteria. Science. 2004;303(5663):1532–5.

Article  CAS  PubMed  Google Scholar 

Blasco A, Rosell A, Castejón R, Coronado MJ, Royuela A, Ramil E, et al. Analysis of NETs (neutrophil extracellular traps) in coronary thrombus and peripheral blood of patients with ST-segment elevation myocardial infarction. Thromb Res marzo de. 2024;235:18–21.

Article  CAS  Google Scholar 

Mangold A, Alias S, Scherz T, Hofbauer T, Jakowitsch J, Panzenböck A, et al. Coronary neutrophil extracellular trap burden and deoxyribonuclease activity in ST-elevation acute coronary syndrome are predictors of ST-segment resolution and infarct size. Circ Res. 2015;116(7):1182–92.

Article  CAS  PubMed  Google Scholar 

Mangold A, Ondracek AS, Hofbauer TM, Scherz T, Artner T, Panagiotides N, et al. Culprit site extracellular DNA and microvascular obstruction in ST-elevation myocardial infarction. Cardiovasc Res. 2022;118(8):2006–17.

Article  CAS  PubMed  Google Scholar 

Langseth MS, Helseth R, Ritschel V, Hansen CH, Andersen GØ, Eritsland J, et al. Double-stranded DNA and NETs components in relation to clinical outcome after ST-elevation myocardial infarction. Sci Rep. 2020;10(1):5007.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hofbauer TM, Mangold A, Ondracek AS, Panzenböck A, Scherz T, Müller J, et al. Deoxyribonuclease 1 Q222R single nucleotide polymorphism and long-term mortality after acute myocardial infarction. Basic Res Cardiol. 2021;116(1):29.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Helseth R, Solheim S, Arnesen H, Seljeflot I, Opstad TB. The Time course of markers of neutrophil extracellular traps in patients undergoing revascularisation for acute myocardial infarction or stable angina pectoris. Mediators Inflamm. 2016;2016:2182358.

Article  PubMed  PubMed Central  Google Scholar 

Ferré-Vallverdú M, Latorre AM, Fuset MP, Sánchez E, Madrid I, Ten F, et al. Neutrophil extracellular traps (NETs) in patients with STEMI. Association with percutaneous coronary intervention and antithrombotic treatments. Thromb Res. 2022;213:78–83.

Article  PubMed  Google Scholar 

Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237–69.

Article  PubMed  Google Scholar 

Perdomo J, Leung HHL, Ahmadi Z, Yan F, Chong JJH, Passam FH, et al. Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia. Nat Commun. 2019;10(1):1322.

Article  PubMed  PubMed Central  Google Scholar 

Laridan E, Denorme F, Desender L, François O, Andersson T, Deckmyn H, et al. Neutrophil extracellular traps in ischemic stroke thrombi. Ann Neurol agosto de. 2017;82(2):223–32.

Article  CAS  Google Scholar 

Schindelin J, Arganda-Carreras I, Frise E, Kaynig V, Longair M, Pietzsch T, et al. Fiji: an open-source platform for biological-image analysis. Nat Methods julio de. 2012;9(7):676–82.

Article  CAS  Google Scholar 

Bonaventura A, Vecchié A, Abbate A, Montecucco F. Neutrophil extracellular traps and cardiovascular diseases: an update. Cells. 2020;9(1):231.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Döring Y, Libby P, Soehnlein O. Neutrophil extracellular traps participate in cardiovascular diseases. Circ Res. 2020;126(9):1228–41.

Article  PubMed  PubMed Central  Google Scholar 

Moschonas IC, Tselepis AD. The pathway of neutrophil extracellular traps towards atherosclerosis and thrombosis. Atherosclerosis. 2019;288:9–16.

Article  CAS  PubMed  Google Scholar 

Abas R, Wozniak M, Herbert KE. P150Mitochondria involvement in NLRP3 inflammasome pathways in monocytes and endothelial cells. Cardiovasc Res. 2018;114(suppl_1):S39-40.

Article  Google Scholar 

Ueki M, Kimura-Kataoka K, Fujihara J, Iida R, Kawai Y, Kusaka A, et al. Evaluation of the functional effects of genetic variants-missense and nonsense SNPs, indels and copy number variations-in the gene encoding human deoxyribonuclease I potentially implicated in autoimmunity. Sci Rep. 2019;9(1): 13660.

Article  PubMed  PubMed Central  Google Scholar