Ahmad M, Mehta P, Reddivari AKR, Mungee S (2025) Percutaneous Coronary Intervention. In: StatPearls. StatPearls Publishing; Accessed April 16, 2025. http://www.ncbi.nlm.nih.gov/books/NBK556123/
GBD Results. Institute for Health Metrics and Evaluation. Accessed April 16 (2025) https://vizhub.healthdata.org/gbd-results
Gori T, Polimeni A, Indolfi C, Räber L, Adriaenssens T, Münzel T (2019) Predictors of stent thrombosis and their implications for clinical practice. Nat Rev Cardiol 16(4):243–256. https://doi.org/10.1038/s41569-018-0118-5
Sv R, Ml O (2025) 2025 ACC/AHA/ACEP/NAEMSP/SCAI guideline for the management of patients with acute coronary syndromes: A report of the American college of Cardiology/American heart association joint committee on clinical practice guidelines. Circulation 151(13). https://doi.org/10.1161/CIR.0000000000001309
Angiolillo DJ, Galli M, Collet JP, Kastrati A, O’Donoghue ML (2022) Antiplatelet therapy after percutaneous coronary intervention. EuroIntervention 17(17):e1371–e1396. https://doi.org/10.4244/EIJ-D-21-00904
Article PubMed PubMed Central Google Scholar
Zhang X, Zhou D, Song S, Huang X, Ding Y, Meng R (2024) Efficacy and safety of long-term dual antiplatelet therapy: a systematic review and meta-analysis. Clin Appl Thromb Hemost 30:10760296241244772. https://doi.org/10.1177/10760296241244772
Article CAS PubMed PubMed Central Google Scholar
Li Y, Li J, Wang B et al (2024) Extended clopidogrel monotherapy vs DAPT in patients with acute coronary syndromes at high ischemic and bleeding risk: the OPT-BIRISK randomized clinical trial. JAMA Cardiol 9(6):523–531. https://doi.org/10.1001/jamacardio.2024.0534
Article PubMed PubMed Central Google Scholar
Jolly SS, Pogue J, Haladyn K et al (2009) Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronary intervention: insights from the PCI-CURE study. Eur Heart J 30(8):900–907. https://doi.org/10.1093/eurheartj/ehn417
Article CAS PubMed Google Scholar
Patrono C, García Rodríguez LA, Landolfi R, Baigent C (2005) Low-dose aspirin for the prevention of atherothrombosis. N Engl J Med 353(22):2373–2383. https://doi.org/10.1056/NEJMra052717
Article CAS PubMed Google Scholar
Hong SJ, Kim JS, Hong SJ et al (2021) 1-month dual-antiplatelet therapy followed by aspirin monotherapy after polymer-free drug-coated stent implantation: one-month DAPT trial. JACC Cardiovasc Interv 14(16):1801–1811. https://doi.org/10.1016/j.jcin.2021.06.003
Liu D, Xu WP, Xu H, Zhao L, Jin DQ (2023) Efficacy and safety of clopidogrel versus aspirin monotherapy for secondary prevention in patients with coronary artery disease: a meta-analysis. Front Cardiovasc Med 10:1265983. https://doi.org/10.3389/fcvm.2023.1265983
Article PubMed PubMed Central Google Scholar
Cappannoli L, Colantuono S, Animati FM et al (2024) Aspirin hypersensitivity in patients with coronary artery disease: an updated review and practical recommendations. Biomolecules 14(10):1329. https://doi.org/10.3390/biom14101329
Article CAS PubMed PubMed Central Google Scholar
Galli M, Cortellini G, Occhipinti G, Rossini R, Romano A, Angiolillo DJ (2024) Aspirin hypersensitivity in patients with atherosclerotic cardiovascular disease. J Am Coll Cardiol 84(18):1748–1766. https://doi.org/10.1016/j.jacc.2024.05.084
Choi KH, Park YH, Lee JY et al (2025) Efficacy and safety of clopidogrel versus aspirin monotherapy in patients at high risk of subsequent cardiovascular event after percutaneous coronary intervention (SMART-CHOICE 3): a randomised, open-label, multicentre trial. Lancet 405(10486):1252–1263. https://doi.org/10.1016/S0140-6736(25)00449-0
Article CAS PubMed Google Scholar
PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews | The BMJ. Accessed April 16 (2025) https://www.bmj.com/content/372/bmj.n160.short
RoB 2: a revised tool for assessing risk of bias in randomised trials | The BMJ. Accessed April 16 (2025) https://www.bmj.com/content/366/bmj.l4898
Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22(4):719–748
Furuya-Kanamori L, Barendregt JJ, Doi SAR (2018) A new improved graphical and quantitative method for detecting bias in meta-analysis. Int J Evid Based Healthc 16(4):195–203. https://doi.org/10.1097/XEB.0000000000000141
Tan BEX, Wong PY, Baibhav B et al (2023) Clopidogrel vs aspirin monotherapy following dual antiplatelet therapy after percutaneous coronary intervention: a systematic review and meta-analysis. Curr Probl Cardiol 48(8):101174. https://doi.org/10.1016/j.cpcardiol.2022.101174
Choi KH, Park YH, Lee JY et al (2025) Efficacy and safety of clopidogrel versus aspirin monotherapy in patients at high risk of subsequent cardiovascular event after percutaneous coronary intervention (SMART-CHOICE 3): a randomised, open-label, multicentre trial. Lancet. https://doi.org/10.1016/S0140-6736(25)00449-0
Watanabe H, Natsuaki M, Morimoto T et al (2024) Aspirin vs. clopidogrel monotherapy after percutaneous coronary intervention: 1-year follow-up of the STOPDAPT-3 trial. Eur Heart J 45(47):5042–5054. https://doi.org/10.1093/eurheartj/ehae617
Article CAS PubMed Google Scholar
Adenosine Diphosphate Receptor Inhibitor - an overview | ScienceDirect Topics. Accessed April 7 (2025) https://www.sciencedirect.com/topics/medicine-and-dentistry/adenosine-diphosphate-receptor-inhibitor
Warner TD, Nylander S, Whatling C (2011) Anti-platelet therapy: cyclo-oxygenase inhibition and the use of aspirin with particular regard to dual anti-platelet therapy. Br J Clin Pharmacol 72(4):619–633. https://doi.org/10.1111/j.1365-2125.2011.03943.x
Article CAS PubMed PubMed Central Google Scholar
Kyrle PA, Eichler HG, Jäger U, Lechner K (1987) Inhibition of prostacyclin and thromboxane A2 generation by low-dose aspirin at the site of plug formation in man in vivo. Circulation 75(5):1025–1029. https://doi.org/10.1161/01.cir.75.5.1025
Article CAS PubMed Google Scholar
Dzeshka MS, Shantsila A, Lip GYH (2016) Effects of aspirin on endothelial function and hypertension. Curr Hypertens Rep 18(11):83. https://doi.org/10.1007/s11906-016-0688-8
Article CAS PubMed PubMed Central Google Scholar
Murphy E, Curneen JMG, McEvoy JW (2021) Aspirin in the modern era of cardiovascular disease prevention. Methodist Debakey Cardiovasc J 47. https://doi.org/10.14797/mdcvj.293
Article PubMed PubMed Central Google Scholar
Collet JP, Thiele H, Barbato E et al (2021) 2020 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: the task force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European society of cardiology (ESC). Eur Heart J 42(14):1289–1367. https://doi.org/10.1093/eurheartj/ehaa575
Watanabe H, Morimoto T, Natsuaki M et al (2024) Clopidogrel vs aspirin monotherapy beyond 1 year after percutaneous coronary intervention. J Am Coll Cardiol 83(1):17–31. https://doi.org/10.1016/j.jacc.2023.10.013
Article CAS PubMed Google Scholar
Mak KH, Bhatt DL, Shao M (2009) Ethnic variation in adverse cardiovascular outcomes and bleeding complications in the clopidogrel for high atherothrombotic risk and ischemic stabilization, management, and avoidance (CHARISMA) study. Am Heart J 157(4):658–665. https://doi.org/10.1016/j.ahj.2008.08.031
Article CAS PubMed Google Scholar
Kitamura A, Nakagawa Y, Sato M et al (2006) Proportions of stroke subtypes among men and women > or = 40 years of age in an urban Japanese City in 1992, 1997, and 2002. Stroke 37(6):1374–1378. https://doi.org/10.1161/01.STR.0000221714.96986.5f
Cho H, Kang J, Kim HS, Park KW (2020) Ethnic differences in oral antithrombotic therapy. Korean Circ J 50(8):645–657. https://doi.org/10.4070/kcj.2020.0098
Article CAS PubMed PubMed Central Google Scholar
Koo BK, Kang J, Park KW et al (2021) Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial. Lancet 397(10293):2487–2496. https://doi.org/10.1016/S0140-6736(21)01063-1
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