Patil SP, Ayappa IA, Caples SM, et al. Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2019;15(2):335–43. https://doi.org/10.5664/jcsm.7640.

Article  PubMed  PubMed Central  Google Scholar 

Patruno V, Aiolfi S, Costantino G, et al. Fixed and autoadjusting continuous positive airway pressure treatments are not similar in reducing cardiovascular risk factors in patients with obstructive sleep apnea. Chest. 2007;131(5):1393–9. https://doi.org/10.1378/chest.06-2192.

Article  PubMed  Google Scholar 

Pépin JL, Tamisier R, Baguet JP, et al. Fixed-pressure CPAP versus auto-adjusting CPAP: comparison of efficacy on blood pressure in obstructive sleep apnoea, a randomised clinical trial. Thorax. 2016;71(8):726–33. https://doi.org/10.1136/thoraxjnl-2015-207700.

Article  PubMed  Google Scholar 

Kaneko Y, Floras JS, Usui K, et al. Cardiovascular effects of continuous positive airway pressure in patients with heart failure and obstructive sleep apnea. N Engl J Med. 2003;348(13):1233–41. https://doi.org/10.1056/NEJMoa022479.

Article  PubMed  Google Scholar 

Smith LA, Vennelle M, Gardner RS, et al. Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo-controlled trial. Eur Heart J. 2007;28(10):1221–7. https://doi.org/10.1093/eurheartj/ehm131.

Article  PubMed  Google Scholar 

Hall AB, Ziadi MC, Leech JA, et al. Effects of short-term continuous positive airway pressure on myocardial sympathetic nerve function and energetics in patients with heart failure and obstructive sleep apnea: a randomized study. Circulation. 2014;130(11):892–901. https://doi.org/10.1161/CIRCULATIONAHA.113.005893.

Article  PubMed  Google Scholar 

Sun H, Shi J, Li M, et al. Impact of continuous positive airway pressure treatment on left ventricular ejection fraction in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials. PLoS ONE. 2013;8(5): e62298. https://doi.org/10.1371/journal.pone.0062298.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mansfield DR, Gollogly NC, Kaye DM, et al. Controlled trial of continuous positive airway pressure in obstructive sleep apnea and heart failure. Am J Respir Crit Care Med. 2004;169(3):361–6. https://doi.org/10.1164/rccm.200306-752OC.

Article  PubMed  Google Scholar 

Usui K, Bradley TD, Spaak J, et al. Inhibition of awake sympathetic nerve activity of heart failure patients with obstructive sleep apnea by nocturnal continuous positive airway pressure. J Am Coll Cardiol. 2005;45(12):2008–11. https://doi.org/10.1016/j.jacc.2004.12.080.

Article  PubMed  Google Scholar 

Egea CJ, Aizpuru F, Pinto JA, et al. Cardiac function after CPAP therapy in patients with chronic heart failure and sleep apnea: a multicenter study. Sleep Med. 2008;9(6):660–6. https://doi.org/10.1016/j.sleep.2007.06.018.

Article  PubMed  Google Scholar 

Gilman MP, Floras JS, Usui K, et al. Continuous positive airway pressure increases heart rate variability in heart failure patients with obstructive sleep apnoea. Clin Sci (Lond). 2008;114(3):243–9. https://doi.org/10.1042/CS20070172.

Article  PubMed  Google Scholar 

Khayat RN, Abraham WT, Patt B, et al. In-hospital treatment of obstructive sleep apnea during decompensation of heart failure. Chest. 2009;136(4):991–7. https://doi.org/10.1378/chest.09-0597.

Article  PubMed  PubMed Central  Google Scholar 

Khayat RN, Javaheri S, Porter K, et al. In-hospital management of sleep apnea during heart failure hospitalization: a randomized controlled trial. J Card Fail. 2020;26(8):705–12. https://doi.org/10.1016/j.cardfail.2020.06.007.

Article  PubMed  PubMed Central  Google Scholar 

Fox H, Bitter T, Sauzet O, et al. Automatic positive airway pressure for obstructive sleep apnea in heart failure with reduced ejection fraction. Clin Res Cardiol. 2021;110(7):983–92. https://doi.org/10.1007/s00392-020-01701-1.

Article  PubMed  CAS  Google Scholar 

Zhu K, Roisman G, Aouf S, et al. All APAPs are not equivalent for the treatment of sleep disordered breathing: a bench evaluation of eleven commercially available devices. J Clin Sleep Med. 2015;11(7):725–34. https://doi.org/10.5664/jcsm.4844.

Article  PubMed  PubMed Central  Google Scholar 

Karasulu L, Epöztürk PO, Sökücü SN, et al. Improving heart rate variability in sleep apnea patients: differences in treatment with auto-titrating positive airway pressure (APAP) versus conventional CPAP. Lung. 2010;188(4):315–20. https://doi.org/10.1007/s00408-010-9237-4.

Article  PubMed  Google Scholar 

Juhász J, Schillen J, Urbigkeit A, et al. Unattended continuous positive airway pressure titration. Clinical relevance and cardiorespiratory hazards of the method. Am J Respir Crit Care Med. 1996;154(2 Pt 1):359–65. https://doi.org/10.1164/ajrccm.154.2.8756807.

Article  PubMed  Google Scholar 

Shoichiro Y, Anna W, Christian MH, et al. LV structure and function in HFrEF with and without peak-flow-triggered adaptive servo-ventilation–treated sleep-disordered breathing. JACC Heart Fail. 2025. https://doi.org/10.1016/j.jchf.2025.02.016.

Article  Google Scholar