Pagel JF (2009) Excessive daytime sleepiness. Am Fam Physicia 79(5):391–396
Franklin KA, Lindberg E (2015) Obstructive sleep apnea is a common disorder in the population—a review on the epidemiology of sleep apnea. J Thorac Dis 7(8):1311–1322. https://doi.org/10.3978/j.issn.2072-1439.2015.06.11
Article PubMed PubMed Central Google Scholar
Krahn LE, Arand D, Avidan AY et al (2021) Recommended protocols for the multiple sleep latency test and maintenance of wakefulness test in adults: guidance from the American academy of sleep medicine. J Clin Sleep Med 17(12):2489–2498. https://doi.org/10.5664/jcsm.9620
Article PubMed PubMed Central Google Scholar
Littner MR, Kushida CA, Wise MS, Davila DG, Morgenthaler T, Lee-Chiong T et al (2005) Practice parameters for clinical use of the MSLT and the MWT. Sleep 28(1):113–121. https://doi.org/10.1093/sleep/28.1.113
Beaudin A, Raneri J (2021) Cognitive function in a sleep clinic cohort of patients with obstructive sleep apnea. Ann Am Thorac Soc 18(5):865–875. https://doi.org/10.1513/AnnalsATS.202004-313OC
Sforza E, Roche F (2012) Sleep apnea syndrome and cognition. Front Neurol 29(3):87. https://doi.org/10.3389/fneur.2012.00087
Martin MM, Rubin RB (1995) A new measure of cognitive flexibility. Psychol Rep 76(2):623–626. https://doi.org/10.2466/pr0.1995.76.2.623
Ioachimescu OC et al (2024) Hypoxic burden – definitions, pathophysiological concepts, methods of evaluation, and clinical relevance. Respirology 29(1):21–31. https://doi.org/10.1111/resp.14801
Wang Y, Yue W, Zhou B, Zhang J, He Y, Wang M, Hu K (2025) The hourly apnea–hypopnea duration better correlates with OSA related nocturnal hypoxemia and excessive daytime sleepiness than AHI. Nat Sci Sleep 17:1101–1112. https://doi.org/10.2147/NSS.S505702
Article CAS PubMed PubMed Central Google Scholar
Berry RB, Budhiraja R, Gottlieb DJ et al (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events: deliberations of the sleep apnea definitions task force of the American academy of sleep medicine. J Clin Sleep Med 8(5):597–619. https://doi.org/10.5664/jcsm.2172
Article PubMed PubMed Central Google Scholar
Norris D, Clark MS, Shipley S (2016) The Mental Status Examination. Am Fam Physician 94(8):635–641
Ciharova M, Cígler H, Dostálová V et al (2020) Beck depression inventory, second edition: demographic correlates, factor structure and comparison with foreign data. J Psychiatry Clin Pract 24(4):371–379. https://doi.org/10.1080/13651501.2020.1775854
Shahveisi K, Jalali A, Moloudi MR, Moradi S, Maroufi A, Khazaie H (2018) Sleep architecture in patients with primary snoring and obstructive sleep apnea. Basic and Clinical Neuroscience Journal 9(2):147–156. https://doi.org/10.29252/NIRP.BCN.9.2.147
Carskadon MA, Dement WC (2018) Normal Human Sleep: An Overview. In: Principles and Practice of Sleep Medicine, 5th ed. Basic Clin Neurosci 9(2):147–156. https://doi.org/10.29252/NIRP.BCN.9.2.147
Roure N, Gomez S, Mediano O et al (2008) Daytime sleepiness and polysomnography in obstructive sleep apnea patients. Sleep Med 9(7):727–731. https://doi.org/10.1016/j.sleep.2008.02.006
Ayik S, Akhan G, Peker S (2011) Frequency of obesity and concomitant diseases in patients with obstructive sleep apnea syndrome (OSAS). Turk Thorac J 12:105–110. https://doi.org/10.5152/ttd.2011.24
Ernst G, Bosio M, Salvado A, Dibur E, Nigro C, Borsini E (2016) Difference between apnea-hypopnea index (AHI) and oxygen desaturation index (ODI): proportional increase associated with degree of obesity. Sleep Breath 20:1175–1183. https://doi.org/10.1007/s11325-016-1330-3
Article CAS PubMed Google Scholar
Kaw R, Hernandez A, Walker E, Aboussouan L, Mokhlesi B (2009) Determinants of hypercapnia in obese patients with obstructive sleep apnea: a systematic review and meta-analysis of cohort studies. Chest 136:787–796. https://doi.org/10.1378/chest.09-0615
Malhotra A, Ayappa I, Ayas N, Collop N et al (2021) Metrics of sleep apnea severity: beyond the apnea-hypopnea index. Sleep 44(7):zsab030. https://doi.org/10.1093/sleep/zsab030
Article PubMed PubMed Central Google Scholar
Azarbarzin A, Sands SA, Stone KL, Taranto-Montemurro L et al (2019) The hypoxic burden of sleep Apnoea predicted cardiovascular disease-related mortality: the osteoporotic fractures in men study and the sleep heart health study. Eur Heart J 40(14):1149–1157. https://doi.org/10.1093/eurheartj/ehy624
Saraç S, Afsar GC (2020) Effect of mean apnea-hypopnea duration in patients with obstructive sleep apnea on clinical and polysomnography parameter. Sleep Breath 24:77–81. https://doi.org/10.1007/s11325-019-01870-y
Kainulainen S, Töyräs J, Oksenberg A et al (2019) Severity of desaturations reflects OSA-related daytime sleepiness better than AHI. J Clin Sleep Med 15(8):1135–1142. https://doi.org/10.5664/jcsm.7806
Article PubMed PubMed Central Google Scholar
Martins FO, Sacramento JF, Olea E (2021) Chronic intermittent hypoxia induces early-stage metabolic dysfunction independently of adipose tissue deregulation. Antioxidants 10(8):1233. https://doi.org/10.3390/antiox10081233
Article CAS PubMed PubMed Central Google Scholar
Kan-Min Parker (2023) Can J Neurol Sci 50(5):730–737. https://doi.org/10.1017/cjn.2022.303
Zhan G, Serrano F, Fenik P, Hsu R, Kong L, Pratico D et al (2005) NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea. Am J Respir Crit Care Med 172:921–929. https://doi.org/10.1164/rccm.200504-581OC
Article PubMed PubMed Central Google Scholar
Marchi NA, Solehac G, Bergen M et al (2023) Obstructive sleep Apnoea and 5-year cognitive decline in the elderly. Eur Respir J 61:2201621. https://doi.org/10.1183/13993003.01621-2022
Article CAS PubMed PubMed Central Google Scholar
Chen R, Xiong K, Lian Y, Huang J et al (2011) Daytime sleepiness and its determining factors in Chinese obstructive sleep apnea patients. Sleep Breath 15:129–135. https://doi.org/10.1007/s11325-010-0337-4
Jaussent I, Bouyer J, Ancelin ML, Berr C (2012) Excessive sleepiness is predictive of cognitive decline in the elderly. Sleep 35:1201–1207. https://doi.org/10.5665/sleep.2070
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