Sleep architecture and quality of life in comorbid OSA and depression: cross-sectional analysis of the Sydney sleep biobank

Senaratna CV, Perret JL, Lodge CJ, Lowe AJ, Campbell BE, Matheson MC et al (2017) Prevalence of obstructive sleep apnea in the general population: A systematic review. Sleep Med Rev 34:70–81

PubMed  Google Scholar 

Edwards C, Almeida OP, Ford AH (2020) Obstructive sleep apnea and depression: a systematic review and meta-analysis. Maturitas 142:45–54

PubMed  Google Scholar 

Berry RBMDF, Wagner MHMDF, Ryals SMMDF Psychiatry and sleep. In: Berry RBMDF, Wagner MHMDF, Ryals SMMDF, editors. Fundamentals of Sleep Medicine2025. pp. 832–55

Kerner NA, Roose SP (2016) Obstructive sleep apnea is linked to depression and cognitive impairment: evidence and potential mechanisms. Am J Geriatr Psychiatry 24(6):496–508

PubMed  PubMed Central  Google Scholar 

Harris M, Glozier N, Ratnavadivel R, Grunstein RR (2009) Obstructive sleep apnea and depression. Sleep Med Rev 13(6):437–444

PubMed  Google Scholar 

Ejaz SM, Khawaja IS, Bhatia S, Hurwitz TD (2011) Obstructive sleep apnea and depression: a review. Innov Clin Neurosci 8(8):17

PubMed  PubMed Central  Google Scholar 

Douglas N, Young A, Roebuck T, Ho S, Miller BR, Kee K et al (2013) Prevalence of depression in patients referred with snoring and obstructive sleep apnoea. Intern Med J 43(6):630–634

CAS  PubMed  Google Scholar 

Wickwire EM, Cole KV, Dexter RB, Malhotra A, Cistulli PA, Sterling KL et al (2024) Depression and comorbid obstructive sleep apnea: association between positive airway pressure adherence, occurrence of self-harm events, healthcare resource utilization, and costs. J Affect Disord 349:254–261

CAS  PubMed  Google Scholar 

Akashiba T, Kawahara S, Akahoshi T, Omori C, Saito O, Majima T et al (2002) Relationship between quality of life and mood or depression in patients with severe obstructive sleep apnea syndrome. Chest 122(3):861–865

PubMed  Google Scholar 

Hobzova M, Prasko J, Vanek J, Ociskova M, Genzor S, Holubova M et al (2017) Depression and obstructive sleep apnea. Neuro Endocrinol Lett 38(5):343–352

CAS  PubMed  Google Scholar 

Liu H, Peng W, Zhou L, Shen Y, Xu B, Xie J et al (2023) Depression with obstructive sleep apnea lead to high cardiovascular disease morbidity/all-cause mortality: findings from the SHHS cohort. J Sleep Res 32(4):e13828

PubMed  Google Scholar 

Zhao Z, Gao Y, Lin J, Xu R, He Z, Zhao L et al (2023) Association of depression with Long-Term cardiovascular risks in older patients with obstructive sleep apnea. Nat Sci Sleep 15:1033–1043

PubMed  PubMed Central  Google Scholar 

Shahveisi K, Jalali A, Moloudi MR, Moradi S, Maroufi A, Khazaie H (2018) Sleep architecture in patients with primary snoring and obstructive sleep apnea. Basic Clin Neurosci 9(2):147–156

PubMed  PubMed Central  Google Scholar 

Basunia M, Fahmy SA, Schmidt F, Agu C, Bhattarai B, Oke V et al (2016) Relationship of symptoms with sleep-stage abnormalities in obstructive sleep apnea-hypopnea syndrome. J Community Hosp Intern Med Perspect 6(4):32170

PubMed  Google Scholar 

Jiang J, Li Z, Li H, Yang J, Ma X, Yan B (2024) Sleep architecture and the incidence of depressive symptoms in middle-aged and older adults: a community-based study. J Affect Disord 352:222–228

PubMed  Google Scholar 

Ricciardiello A, Teh JZ, Lam AKF, Marshall NS, Naismith SL, D’Rozario AL (2024) Objective measures of sleep in adults and older adults with and without depression: a systematic review and meta-analysis. Sleep Med 124:637–648

PubMed  Google Scholar 

Reynolds CF, Kupfer DJ, McEachran AB, Taska LS, Sewitch DE, Coble PA (1984) Depressive psychopathology in male sleep apneics. J Clin Psychiatry 45(7):287–290

PubMed  Google Scholar 

Bardwell WA, Moore P, Ancoli-Israel S, Dimsdale JE (2000) Does obstructive sleep apnea confound sleep architecture findings in subjects with depressive symptoms? Biol Psychiatry 48(10):1001–1009

CAS  PubMed  Google Scholar 

Amis TC, Sutherland K, Cistulli PA, Aimee L, Melehan K, Piper A et al (2019) Sydney Sleep Biobank (SSB): Development of a research resource

von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP (2007) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med 147(8):573–577

Google Scholar 

Berry RB, Brooks R, Gamaldo C, Harding SM, Lloyd RM, Quan SF et al (2017) AASM scoring manual updates for 2017 (Version 2.4). J Clin Sleep Med 13(5):665–666

PubMed  PubMed Central  Google Scholar 

Nanthakumar S, Bucks RS, Skinner TC, Starkstein S, Hillman D, James A et al (2017) Assessment of the Depression, Anxiety, and stress scale (DASS-21) in untreated obstructive sleep apnea (OSA). Psychol Assess 29(10):1201–1209

PubMed  Google Scholar 

Lovibond SHaL PF Manual for the Depression Anxiety Stress Scales. 2nd ed. Foundation P, editor. Sydney1995

Ohayon MM, Carskadon MA, Guilleminault C, Vitiello MV (2004) Meta-analysis of quantitative sleep parameters from childhood to old age in healthy individuals: developing normative sleep values across the human lifespan. Sleep 27(7):1255–1273

PubMed  Google Scholar 

Krishnan V, Collop NA (2006) Gender differences in sleep disorders. Curr Opin Pulm Med. https://doi.org/10.1097/01.mcp.0000245705.69440.6a

Article  PubMed  Google Scholar 

Rao MN, Blackwell T, Redline S, Stefanick ML, Ancoli-Israel S, Stone KL et al (2009) Association between sleep architecture and measures of body composition. Sleep 32(4):483–490

PubMed  PubMed Central  Google Scholar 

Ghossoub E, Geagea L, Kobeissy F, Talih F (2021) Comparative effects of psychotropic medications on sleep architecture: a retrospective review of diagnostic polysomnography sleep parameters. Sleep Sci 14(3):236–244

PubMed  PubMed Central  Google Scholar 

Wichniak A, Wierzbicka A, Walęcka M, Jernajczyk W (2017) Effects of antidepressants on sleep. Curr Psychiatry Rep 19(9):63

PubMed  PubMed Central  Google Scholar 

Wang H, Hsu W, Chang T, Chang C, Chu S (2025) Sleep architecture changes in depression and Sleep-Related disorders [Abstract]. Int J Neuropsychopharmacol 28(Supplement1):i246–i7

PubMed Central  Google Scholar 

Riemann D, Nissen C (2012) Sleep and psychotropic drugs. In: Espie CA, Morin CM (eds) Oxford handbook of sleep and sleep disorders. Oxford, Oxford

Hutka P, Krivosova M, Muchova Z, Tonhajzerova I, Hamrakova A, Mlyncekova Z et al (2021) Association of sleep architecture and physiology with depressive disorder and antidepressants treatment. Int J Mol Sci 22(3):1333

CAS  PubMed  PubMed Central  Google Scholar 

Basunia RA, Fahmy S, Schmidt MF, Agu C, Bhattarai B, Oke V et al (2015) Sleep architecture in obstructive sleep apnea-hypopnea syndrome (OSAHS) in adult African American population and relationship with apnea hypopnea index (AHI) and Epworth sleepiness scale (ESS). Chest 148(4):354A

Google Scholar 

Wu B, Cai J, Yao Y, Pan Y, Pan L, Zhang L et al (2020) Relationship between sleep architecture and severity of obstructive sleep apnea. Zhejiang Da Xue Xue Bao Yi Xue Ban 49(4):455–461

PubMed  PubMed Central  Google Scholar 

Luo C, Chen W, Li Q (2024) The effect of central sleep apnea on sleep architecture in children with obstructive sleep apnea. Int J Pediatr Otorhinolaryngol 183:112053

PubMed  Google Scholar 

Weiss RB, Aderka IM, Lee J, Beard C, Björgvinsson T (2015) A comparison of three brief depression measures in an acute psychiatric population: CES-D-10, QIDS-SR, and DASS-21-DEP. J Psychopathol Behav Assess 37(2):217–230

Google Scholar 

Gloster AT, Rhoades HM, Novy D, Klotsche J, Senior A, Kunik M et al (2008) Psychometric properties of the depression anxiety and stress scale-21 in older primary care patients. J Affect Disord 110(3):248–259

PubMed  PubMed Central  Google Scholar 

Fuller KH, Waters WF, Binks PG, Anderson T (1997) Generalized anxiety and sleep architecture: a polysomnographic investigation. Sleep 20(5):370–376

CAS  PubMed  Google Scholar 

Haberland L, Höllmer H, Schulz H, Spiegelhalder K, Gorzka R (2019) Changes in sleep architecture in German armed forces personnel with posttraumatic stress disorder compared with depressed and healthy control subjects. PLoS ONE 14(4):e0215355

CAS  PubMed  PubMed Central  Google Scholar 

Luu B, Rodway GW, Rice E (2018) Should we be targeting sleep architecture to more effectively treat schizophrenia? JAAPA 31(12):52–54

PubMed  Google Scholar 

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