Hamdy G, Hendy OM, Mahmoud H, El-sebaey A, Ali SR, Khalaf FA. Haptoglobin phenotypes as a risk factor for coronary artery disease in type 2 diabetes mellitus: an Egyptian study. Egyptian Journal of Medical Human Genetics. 2014;15(3):257–64. https://doi.org/10.1016/j.ejmhg.2014.03.003.
Galicia G, L, J. Haptoglobin Function and Regulation in Autoimmune Diseases. Acute Phase Proteins - Regulation and Functions of Acute Phase Proteins, (June 2017). 2011. https://doi.org/10.5772/22483
Levy AP, Asleh R, Blum S, Levy NS, Miller-Lotan R, Kalet-Litman S, … Goldenstein H. Haptoglobin: basic and clinical aspects. Antioxid Redox Signal. 2010;12:293–304. https://doi.org/10.1089/ars.2009.2793
Naryzny SN, Legina OK. Haptoglobin as a biomarker. Biochem (Moscow) Suppl Series B: Biomed Chem. 2021;15(3):184–98. https://doi.org/10.1134/S1990750821030069.
Lwanira CN, Kironde F, Swedberg G. Haptoglobin gene diversity and incidence of uncomplicated malaria among children in Iganga Uganda. Malar J. 2020;19(1):1–7. https://doi.org/10.1186/s12936-020-03515-y.
Boettger LM, Salem RM, Handsaker RE, Peloso GM, Kathiresan S, Hirschhorn JN, McCarroll SA. Recurring exon deletions in the HP (haptoglobin) gene contribute to lower blood cholesterol levels. Nat Genet. 2016;48(4):359–66. https://doi.org/10.1038/ng.3510.
Article CAS PubMed PubMed Central Google Scholar
Koch W, Latz W, Eichinger M, Roguin A, Levy AP, Schömig A, Kastrati A. Genotyping of the common haptoglobin Hp 1/2 polymorphism based on PCR. Clin Chem. 2002;48(9):1377–82. https://doi.org/10.1093/clinchem/48.9.1377.
Article CAS PubMed Google Scholar
MacKellar M, Vigerust DJ. Role of haptoglobin in health and disease: a focus on diabetes. Clinical Diabetes. 2016;34(3):148–57. https://doi.org/10.2337/diaclin.34.3.148.
Article PubMed PubMed Central Google Scholar
Wan S-G, Wang M, Zhang X, Ji G. Progress on haptoglobin and metabolic diseases. World J Diabetes. 2021;12(3):206–14. https://doi.org/10.4239/wjd.v12.i3.206.
Article PubMed PubMed Central Google Scholar
Andersen CBF, Torvund-Jensen M, Nielsen MJ, De Oliveira CLP, Hersleth HP, Andersen NH, … Moestrup SK. Structure of the haptoglobinhaemoglobin complex. Nature. 2012;489(7416):L456–459. https://doi.org/10.1038/nature11369
Asghar M, Achoubi N, Meitei SY, Meitei KS, Murry B, Sachdeva MP, Saraswathy KN. Haptoglobin polymorphism among three populations of Manipur, India: a critical analysis. Internet J Biol Anthropol. 2009;3(2):2–5. https://doi.org/10.5580/71c.
Khurana P, Aggarwal A, Huidrom SS, Kshatriya GK. Haptoglobin polymorphism among the tribal groups of southern Gujarat. Indian J Human Genet. 2011;17(3):169–74. https://doi.org/10.4103/0971-6866.92096.
Wobeto VPA, da Cunha Pinho P, Souza JRM, Zaccariotto TR, de FátimaZonati M. Haptoglobin genotypes and refractory hypertension in type 2 diabetes mellitus patients. Arq Bras Cardiol. 2011;97(4):338–45. https://doi.org/10.1590/S0066-782X201100500010.
Article CAS PubMed Google Scholar
Adinortey, Adjimani JP, Nyarko PE, Sarpong C, Tsikata FY, Nyarko AK. Haptoglobin polymorphism and association with complications in Ghanaian type 2 diabetic patients. Indian J Clin Biochem. 2011;26(4):366–372. https://doi.org/10.1007/s12291-011-0141-3
Moussa A, Rejeb J, Omezzine A, Rebhi L, Boumaiza I, Kacem S, … Bouslama A. Association between haptoglobin 2–2 genotype and coronary artery disease and its severity in a Tunisian population. Biochem Genet 2014;52(5–6):269–282. https://doi.org/10.1007/s10528-014-9646-9
Burghardt* KJ, 1, DanaElMasri1, Sabrina E Dass2, SSS, Linda Aj. Association between haptoglobin gene and insulin resistance in Arab–Americans. Clin Res Cardiol. 2019;108(5):520–538. https://doi.org/10.1007/s00392-018-1381-5
Pechlaner R, Kiechl S, Willeit P, Demetz E, Haun M, Weger S, … Willeit J. Haptoglobin 2–2 genotype is not associated with cardiovascular risk in subjects with elevated glycohemoglobin-results from the Bruneck Study. J Am Heart Assoc. 2014;3(3):1–9. https://doi.org/10.1161/JAHA.113.000732
Sunderland E, Sawhney KS, Cartwright RA, Jolly JG. Studies of haptoglobin and transferrin types in four castes of the Panjab Northern India. Human Hered. 1976;26(1):16–24. https://doi.org/10.1159/000152779.
Baxi AJ, Camoens H. Studies on haptoglobin types in various Indian populations. Hum Hered. 1969;19(1):65–70. https://doi.org/10.1159/000152200.
Article CAS PubMed Google Scholar
Joshi KJ, Shah BT, Rathod VR. Haptoglobin revisited. Int J Sci Res Publ (IJSRP). 2018;8(9):506–10. https://doi.org/10.29322/ijsrp.8.9.2018.p8170.
Dasgupta S, Samtani R, Saraswathy KN. Haptoglobin polymorphism among Warli tribe of Dadra Nagar Haveli India. Anthropologist. 2008;10(4):315–6. https://doi.org/10.1080/09720073.2008.11891070.
Dalan R, Liew H, Goh LL, Gao X, Chew DEK, Boehm BO, Leow MKS. The haptoglobin 2–2 genotype is associated with inflammation and carotid artery intima-media thickness. Diab Vasc Dis Res. 2016;13(5):373–6. https://doi.org/10.1177/1479164116645247.
Article CAS PubMed Google Scholar
Puneet, Upadhyay AK, Kaur M, Singh RD. Assessment of haptoglobin 2-2 genotype in type 2 diabetes and cardiovascular patients in North Indian population: a case-control study. J Clin Diagn Res. 2023;17(1):6–10. https://doi.org/10.7860/jcdr/2023/57707.17340
Costacou T, Levy AP. Haptoglobin genotype and its role in diabetic cardiovascular disease. J Cardiovasc Transl Res. 2012;5(4):423–35. https://doi.org/10.1007/s12265-012-9361-z.
Article PubMed PubMed Central Google Scholar
Moreno PR, Purushothaman KR, Purushothaman M, Muntner P, Levy NS, Fuster V, … Levy AP. Haptoglobin genotype is a major determinant of the amount of iron in the human atherosclerotic plaque. J Am College Cardiol. 2008;52(13):1049–1051. https://doi.org/10.1016/j.jacc.2008.06.029
Cahill LE, Jensen MK, Chiuve SE, Shalom H, Pai JK, Flint AJ, … Rimm EB. The risk of coronary heart disease associated with glycosylated hemoglobin of 6.5% or greater is pronounced in the haptoglobin 2–2 genotype. J Am College Cardiol 2015;66(16):1791–1799. https://doi.org/10.1016/j.jacc.2015.07.076
Carew AS, Levy AP, Ginsberg HN, Coca S, Lache O, Ransom T, … Cahill LE. Haptoglobin phenotype modifies the influence of intensive glycemic control on cardiovascular outcomes. J Am Coll Cardiol 2020;75(5):512–521. https://doi.org/10.1016/j.jacc.2019.11.051
Cubedo J, Padró T, García-Arguinzonis M, Vilahur G, Miñambres I, Pou JM, … Badimon L. A novel truncated form of apolipoprotein A-I transported by dense LDL is increased in diabetic patients. J Lipid Res. 2015;56(9):1762–1773. https://doi.org/10.1194/jlr.P057513
Amoorthy RKK, Kaliaperumal R, Achalam R, Poovitha R, Rajagopalan G. Apolipoproteins an early and better diagnostic marker for diabetic retinopathy. J Clin Diagn Res. 2017;11(10):NC01–NC05. https://doi.org/10.7860/JCDR/2017/28687.10710
Zhang P, Gao J, Pu C, Zhang Y. Apolipoprotein status in type 2 diabetes mellitus and its complications (Review). Mol Med Rep. 2017;16:9279–86. https://doi.org/10.3892/mmr.2017.7831.
Article CAS PubMed Google Scholar
Shi X, Sun L, Wang L, Jin F, Sun J, Zhu X, … Yang Z. Haptoglobin 2–2 genotype is associated with increased risk of type 2 diabetes mellitus in northern Chinese. Genet Test Mol Biomark. 2012;16(6):563–568. https://doi.org/10.1089/gtmb.2011.0246
Quaye IK, Ababio G, Amoah AG. Haptoglobin 2–2 phenotype is a risk factor for type 2 diabetes in Ghana. J Atheroscler Thromb. 2006;13(2):90–4. https://doi.org/10.5551/jat.13.90.
HocHberg I, Berinstein EM, Milman U, Shapira C, Levy AP. Interaction between the haptoglobin genotype and vitamin E on cardiovascular disease in diabetes. Curr Diabetes Rep. 2017;17(6). https://doi.org/10.1007/s11892-017-0868-1
Seferović JP, Ašanin M, Seferović PM. Haptoglobin and haptoglobin genotypes in diabetes: a silver bullet to identify the responders to antioxidant therapy? Eur J Prev Cardiol. 2018;25(14):1498–501. https://doi.org/10.1177/2047487318794521.
Soejima M, Koda Y. Haptoglobin polymorphisms in Latin American populations. Sci Rep. 2020;10(1):1–8. https://doi.org/10.1038/s41598-020-70755-y.
Froguel P, Ndiaye NC, Bonnefond A, Bouatia-Naji N, Dechaume A, Siest G, … Visvikis-Siest S. A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels. PLoS ONE 2012;7(3):1–9. https://doi.org/10.1371/journal.pone.0032327
Bjornsson E, Helgason H, Halldorsson G, Helgadottir A, Gylfason A, Kehr B, … Stefansson K. A rare splice donor mutation in the haptoglobin gene associates with blood lipid levels and coronary artery disease. Human Mol Genet. 2017;26(12):2364–2376. https://doi.org/10.1093/hmg/ddx123
Einarson TR, Acs A, Ludwig C, Panton UH. Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007–2017. Cardiovasc Diabetol. 2018;17(1):1–19. https://doi.org/10.1186/s12933-018-0728-6.
Jelena A, Mirjana M, Desanka B, Svetlana IM, Aleksandra U, Goran P, Ilijana G. Haptoglobin and the inflammatory and oxidative status in experimental diabetic rats: antioxidant role of haptoglobin. J Physiol Biochem. 2013;69(1):45–58. https://doi.org/10.1007/s13105-012-0186-7.
Article CAS PubMed Google Scholar
Buchan DWA, Jones DT. The PSIPRED protein analysis workbench: 20 years on. Nucleic Acids Res. 2019;47(April):402–7. https://doi.org/10.1093/nar/gkz297.
Ziegler M, Wallert M, Lorkowski S, Peter K. Cardiovascular and metabolic protection by vitamin E: a matter of treatment strategy? Antioxidants. 2020;9:1–40. https://doi.org/10.3390/antiox9100935.
Yerbury JJ, Mark S, Easterbrook-SmithCindy RB, Wilson HR. The acute phase protein haptoglobin is a mammalian extracellular chaperone with an action similar to clusterin. Biochemistry. 2005;44(32):10914–25. https://doi.org/10.1021/bi050764x.
Comments (0)