Exosomes from Cancer Cells: Innovative Approach for Targeted Cancer Treatment

Lee Y, El Andaloussi S, Wood MJA. Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy. Hum Mol Genet. 2012;21(R1):R125–34.

Article  CAS  PubMed  Google Scholar 

Hartjes TA, et al. Extracellular vesicle quantification and characterization: common methods and emerging approaches. Bioengineering. 2019;6(1):7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Srivastava A, et al. Progress in extracellular vesicle biology and their application in cancer medicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2020;12(4):e1621.

Article  PubMed  PubMed Central  Google Scholar 

Johnstone RM, et al. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem. 1987;262(19):9412–20.

Article  CAS  PubMed  Google Scholar 

Šupić G. The nobel prize in physiology or medicine 2013. Mil Med Pharm J Serbia. 2013;70:991.

Witwer KW, Théry C. Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature. J Extracell Vesicles. 2019;8(1):1648167.

Article  PubMed  PubMed Central  Google Scholar 

Kumar MA, et al. Extracellular vesicles as tools and targets in therapy for diseases. Signal Transduct Target Ther. 2024;9(1):27.

Article  PubMed  PubMed Central  Google Scholar 

Xu Z, et al. Exosome-based immunotherapy: a promising approach for cancer treatment. Mol Cancer. 2020;19:1–16.

Article  Google Scholar 

Bastos N, Ruivo CF, da Silva S, Melo SA. Exosomes in cancer: use them or target them?. In: Seminars in cell & developmental biology. 2018(Jun 1);78:13–21.

Mincheva‐Nilsson L et al (2016) Isolation and characterization of exosomes from cultures of tissue explants and cell lines. Current protocols in immunology 115(1): 14.42. 1–14.42. 21.

Valadi H, et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9(6):654–9.

Article  CAS  PubMed  Google Scholar 

Aqil F, Gupta RC. Exosomes in cancer therapy. Cancers. 2022;14:500.

Gurunathan S, et al. Palladium nanoparticle-induced oxidative stress, endoplasmic reticulum stress, apoptosis, and immunomodulation enhance the biogenesis and release of exosome in human leukemia monocytic cells (THP-1). Int J Nanomed. 2021;2849–2877.

Gurung S, et al. The exosome journey: from biogenesis to uptake and intracellular signalling. Cell Commun Signaling. 2021;19(1):1–19.

Article  Google Scholar 

Sil S, et al. Strategies for the use of extracellular vesicles for the delivery of therapeutics. J Neuroimmune Pharmacol. 2020;15:422–42.

Article  PubMed  Google Scholar 

Yong T, et al. Extracellular vesicles for tumor targeting delivery based on five features principle. J Control Release. 2020;322:555–65.

Article  CAS  PubMed  Google Scholar 

Wang X, et al. Cell-derived exosomes as promising carriers for drug delivery and targeted therapy. Curr Cancer Drug Targets. 2018;18(4):347–54.

Article  CAS  PubMed  Google Scholar 

Di Bella MA. Overview and update on extracellular vesicles: considerations on exosomes and their application in modern medicine. Biology. 2022;11(6):804–831.

Doyle LM, Wang MZ. Overview of extracellular vesicles, their origin, composition, purpose, and methods for exosome isolation and analysis. Cells. 2019;8(7):727–751.

Liu M-L, Williams K, Werth V. Microvesicles in autoimmune diseases. Adv Clin Chem. 2016;77:125–75.

Article  CAS  PubMed  Google Scholar 

Ratajczak MZ, Ratajczak J. Extracellular microvesicles/exosomes: discovery, disbelief, acceptance, and the future? Leukemia. 2020;34(12):3126–35.

Article  PubMed  PubMed Central  Google Scholar 

Yu L, et al. Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials. J Nanobiotechnol. 2023;21(1):218.

Article  Google Scholar 

Vishnubhatla I, et al. The development of stem cell-derived exosomes as a cell-free regenerative medicine. J Circulating Biomarkers. 2014;3:2.

Article  Google Scholar 

Zhang Y, et al. Exosomes: biogenesis, biologic function and clinical potential. Cell Biosci. 2019;9:1–18.

Article  Google Scholar 

Thakur A, et al. The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics. Protein Cell. 2022;13(9):631–54.

Article  PubMed  Google Scholar 

Chaput N, Théry C. Exosomes: immune properties and potential clinical implementations. In: Seminars in immunopathology. 2011;33:419–440.

Debbi L, et al. Boosting extracellular vesicle secretion. Biotechnol Adv. 2022;59:107983.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bussard KM, et al. Tumor-associated stromal cells as key contributors to the tumor microenvironment. Breast Cancer Res. 2016;18:1–11.

Article  Google Scholar 

Steinbichler TB, et al. The role of exosomes in cancer metastasis. In: Seminars in cancer biology. 2017;44:170–181.

Paskeh MDA, et al. Emerging role of exosomes in cancer progression and tumor microenvironment remodeling. J Hematol Oncol. 2022;15(1):1–39.

Article  Google Scholar 

Kim SB. Function and therapeutic development of exosomes for cancer therapy. Arch Pharmacal Res. 2022;45(5):295–308.

Article  CAS  Google Scholar 

Mashouri L, et al. Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance. Mol Cancer. 2019;18:1–14.

Article  Google Scholar 

Abels ER, Breakefield XO. Introduction to extracellular vesicles: biogenesis, RNA cargo selection, content, release, and uptake. Cell Mol Neurobiol. 2016;36:301–12.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fontana F, et al. Extracellular vesicles: emerging modulators of cancer drug resistance. Cancers. 2021;13(4):749.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Escrevente C, et al. Interaction and uptake of exosomes by ovarian cancer cells. BMC Cancer. 2011;11:1–10.

Article  Google Scholar 

Chen H, et al. Tumor-derived exosomes: nanovesicles made by cancer cells to promote cancer metastasis. Acta Pharmaceutica Sinica B. 2021;11(8):2136–49.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang X, et al. The key role of exosomes on the pre-metastatic niche formation in tumors. Front Mol Biosci. 2021;8:703640.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zeng Z, et al. Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis. Nat Commun. 2018;9(1):5395.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou W, et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell. 2014;25(4):501–15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Agrahari V, et al. Extracellular microvesicles as new industrial therapeutic frontiers. Trends Biotechnol. 2019;37(7):707–29.

Article  CAS  PubMed  Google Scholar 

Li X-Q, et al. Exosomes derived from gefitinib-treated EGFR-mutant lung cancer cells alter cisplatin sensitivity via up-regulating autophagy. Oncotarget. 2016;7(17):24585.

Article  PubMed  PubMed Central  Google Scholar 

Rahbarghazi R, et al. Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications. Cell Commun Signal. 2019;17:1–17.

Article  Google Scholar 

Rabinowits G, et al. Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer. 2009;10(1):42–6.

Article 

Comments (0)

No login
gif