Prognostic effect of the combined use of thiazides and loop diuretics at discharge following a hospitalization for acute heart failure

Gracia E, Singh P, Collins S, Chioncel O, Pang P, Butler J (2018) The vulnerable phase of heart failure. Am J Ther 25:e456–e464. https://doi.org/10.1097/MJT.0000000000000794

Article  PubMed  PubMed Central  Google Scholar 

Dharmarajan K, Hsieh AF, Lin Z et al (2013) Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia. JAMA 309:355–363. https://doi.org/10.1001/jama.2012.216476

Article  CAS  PubMed  PubMed Central  Google Scholar 

Llorens P, Javaloyes P, Martín-Sánchez FJ, ICA-SEMES Research Group et al (2018) Time trends in characteristics, clinical course, and outcomes of 13,791 patients with acute heart failure. Clin Res Cardiol 107:897–913. https://doi.org/10.1007/s00392-018-1261-z

Article  PubMed  Google Scholar 

Bueno H, Ross JS, Wang Y et al (2010) Trends in length of stay and short–term outcomes among medicare patients hospitalized for heart failure, 1993–2006. JAMA 303:2141–2147. https://doi.org/10.1001/jama.2010.748

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fudim M, Parikh KS, Dunning A et al (2018) Relation of volume overload to clinical outcomes in acute heart failure (from ASCEND-HF). Am J Cardiol 122:1506–1512. https://doi.org/10.1016/j.amjcard.2018.07.023

Article  PubMed  PubMed Central  Google Scholar 

Lala A, McNulty SE, Mentz RJ et al (2015) Relief and recurrence of congestion during and after hospitalization for acute heart failure: insights from diuretic optimization strategy evaluation in acute decompensated heart failure (DOSE-AHF) and cardiorenal rescue study in acute decompensated heart failure (CARESS-HF). Circ Heart Fail 8:741–748. https://doi.org/10.1161/CIRCHEARTFAILURE.114.001957

Article  PubMed  PubMed Central  Google Scholar 

Ambrosy AP, Pang PS, Khan S, EVEREST Trial Investigators et al (2013) Clinical course and predictive value of congestion during hospitalization in patients admitted for worsening signs and symptoms of heart failure with reduced ejection fraction: findings from the EVEREST trial. Eur Heart J 34:835–843. https://doi.org/10.1093/eurheartj/ehs444

Article  PubMed  Google Scholar 

Rubio-Gracia J, Demissei BG, Ter Maaten JM et al (2018) Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure. Int J Cardiol 258:185–191. https://doi.org/10.1016/j.ijcard.2018.01.067

Article  PubMed  Google Scholar 

Al-Naher A, Wright D, Devonald MAJ, Pirmohamed M (2018) Renal function monitoring in heart failure—what is the optimal frequency? A narrative review. Br J Clin Pharmacol 84:5–17. https://doi.org/10.1111/bcp.13434

Article  PubMed  Google Scholar 

Mullens W, Dauw J, Martens P, ADVOR Study Group et al (2022) Acetazolamide in acute decompensated heart failure with volume overload. N Engl J Med 387:1185–1195. https://doi.org/10.1056/NEJMoa2203094

Article  CAS  PubMed  Google Scholar 

Trullàs JC, Morales-Rull JL, Casado J, CLOROTIC trial investigators et al (2023) Combining loop with thiazide diuretics for decompensated heart failure: the CLOROTIC trial. Eur Heart J 44:411–421. https://doi.org/10.1093/eurheartj/ehac689

Article  CAS  PubMed  Google Scholar 

McDonagh TA, Metra M, Adamo M, ESC Scientific Document Group et al (2021) 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42:3599–3726. https://doi.org/10.1093/eurheartj/ehab368

Article  CAS  PubMed  Google Scholar 

ALCALOTIC study. Metabolic alkalosis in heart failure. ClinicalTrials.gov ID NCT04740242. Available at ClinicalTrials.gov. https://classic.clinicaltrials.gov/ct2/show/NCT04740242

Fudim M, O’Connor CM, Mulder H et al (2018) Loop diuretic adjustments in patients with chronic heart failure: insights from HF-ACTION. Am Heart J 205:133–141. https://doi.org/10.1016/j.ahj.2018.06.017

Article  CAS  PubMed  PubMed Central  Google Scholar 

Núñez E, Steyerberg EW, Núñez J (2011) regression modeling strategies. Rev Esp Cardiol (English Ed) 64:501–507. https://doi.org/10.1016/j.recesp.2011.01.019

Article  Google Scholar 

Mullens W, Damman K, Harjola VP et al (2019) The use of diuretics in heart failure with congestion—a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 21:137–155. https://doi.org/10.1002/ejhf.1369

Article  PubMed  Google Scholar 

Trullàs JC, Casado J, Morales-Rull JL et al (2019) Prevalence and outcome of diuretic resistance in heart failure. Intern Emerg Med 14:529–537. https://doi.org/10.1007/s11739-018-02019-7

Article  PubMed  Google Scholar 

Trullàs JC, Morales-Rull JL, Casado J (2023) Combining loop and thiazide diuretics for acute heart failure across the estimated glomerular filtration rate spectrum: a post-hoc analysis of the CLOROTIC trial. Eur J Heart Fail 25:1784–1793. https://doi.org/10.1002/ejhf.2988

Article  CAS  PubMed  Google Scholar 

Felker GM, Ellison DH, Mullens W, Cox ZL, Testani JM (2020) Diuretic therapy for patients with heart failure: JACC state-of-the-art review. J Am Coll Cardiol 75:1178–1195. https://doi.org/10.1016/j.jacc.2019.12.059

Article  CAS  PubMed  Google Scholar 

Mouallem M, Brif I, Mayan H, Farfel Z (1995) Prolonged therapy by the combination of furosemide and thiazides in refractory heart failure and other fluid retaining conditions. Int J Cardiol 50:89–94. https://doi.org/10.1016/0167-5273(95)93677-k

Article  CAS  PubMed  Google Scholar 

Jentzer JC, DeWald TA, Hernandez AF (2010) Combination of loop diuretics with thiazide-type diuretics in heart failure. J Am Coll Cardiol 56:1527–1534. https://doi.org/10.1016/j.jacc.2010.06.034

Article  CAS  PubMed  Google Scholar 

Sciarretta S, Palano F, Tocci G et al (2011) Antihypertensive treatment and development of heart failure in hypertension: a Bayesian network meta-analysis of studies in patients with hypertension and high cardiovascular risk. Arch Intern Med 171:384–394. https://doi.org/10.1001/archinternmed.2010.427

Article  PubMed  Google Scholar 

Ernst ME, Fravel MA (2022) Thiazide and the thiazide-like diuretics: review of hydrochlorothiazide, chlorthalidone, and indapamide. Am J Hypertens 35:573–586. https://doi.org/10.1093/ajh/hpac048

Article  CAS  PubMed  Google Scholar 

Knauf H, Mutschler E (1995) Diuretic effectiveness of hydrochlorothiazide and furosemide alone and in combination in chronic renal failure. J Cardiovasc Pharmacol 26:394–400. https://doi.org/10.1097/00005344-199509000-00008

Article  CAS  PubMed  Google Scholar 

Gogikar A, Nanda A, Janga LSN et al (2023) Combination diuretic therapy with thiazides: a systematic review on the beneficial approach to overcome refractory fluid overload in heart failure. Cureus 15:e44624. https://doi.org/10.7759/cureus.44624

Article  PubMed  PubMed Central  Google Scholar 

de la Espriella R, Cobo M, Santas E et al (2023) Assessment of filling pressures and fluid overload in heart failure: an updated perspective. Rev Esp Cardiol (Engl Ed) 76:47–57. https://doi.org/10.1016/j.rec.2022.07.009

Article  PubMed  Google Scholar 

Comments (0)

No login
gif