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Mechanism of external K + sensitivity of KCNQ1 channels
Occupation of the uppermost ion-binding site of the selectivity filter of K+ channels by external K+ promotes channel acti...
A cooperative knock-on mechanism underpins Ca 2+ -selective cation permeation in TRPV channels
TRPV5 and TRPV6 are unique among TRP channels due to their high Ca2+ selectivity, while most other members of this ion cha...
Sensing its own permeant ion: KCNQ1 channel inhibition by external K +
External potassium inhibits KCNQ1 channel through a mechanism involving increased occupancy of the filter S0 site by K+o.
About hysteresis in Shaker: Response to note by Villalba-Galea
Our response points out the deficiencies in the alternative explanation proposed by Villalba-Galea to account for our find...
About hysteresis in Shaker: A note on Cowgill and Chanda
This letter proposes an alternative explanation to the work published by Cowgill and Chanda on the nature of hysteresis in...
BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy
A heterozygous BK channelopathy G375R/WT expresses five different types of channels differing in voltage activation and co...
Tweaking the catalytic efficiency of the CFTR ion channel
CFTR, unique among ABC transporters, evolved to function as an ion channel in part by optimizing the stability of the open...