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Re-evaluating the relevance of extensive intraductal component (EIC) in modern breast cancer management
Re-evaluating the relevance of extensive intraductal component (EIC) in modern breast cancer management
The concept of extensive intraductal component (EIC), currently defined by the presence of a prominent ductal carcinoma in...
Real-time histological evaluation of gastrointestinal tissue using non-linear microscopy
Real-time histological evaluation of gastrointestinal tissue using non-linear microscopy
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Unravelling switch/sucrose non-fermentable (SWI-SNF) complex-deficient thoracic tumours: a clinicopathological comparative on undifferentiated tumours and non-small cell lung carcinomas with BRG1 and BRM deficiency
Unravelling switch/sucrose non-fermentable (SWI-SNF) complex-deficient thoracic tumours: a clinicopathological comparative on undifferentiated tumours and non-small cell lung carcinomas with BRG1 and BRM deficiency
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Computational pathology identifies a low B-cell content in the tumour microenvironment as a predictor of adverse outcome in patients with classic Hodgkin lymphoma treated with ABVD
Computational pathology identifies a low B-cell content in the tumour microenvironment as a predictor of adverse outcome in patients with classic Hodgkin lymphoma treated with ABVD
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Breast phyllodes tumour with epithelioid feature predisposes to malignant transformation
Breast phyllodes tumour with epithelioid feature predisposes to malignant transformation
WHAT IS ALREADY KNOWN ON THIS TOPICThe stromal cells of classic phyllodes tumour (PT) exhibit a spindle cell morphology, w...
Partial regression of conventional renal cell carcinoma displays markers of wound repair
Partial regression of conventional renal cell carcinoma displays markers of wound repair
WHAT IS ALREADY KNOWN ON THIS TOPICHOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICYIntroductionSpontaneous regress...
Novel and unusual USP6 fusion partners in aneurysmal bone cyst and their role in pathogenesis and histopathological evaluation of this disease
Novel and unusual USP6 fusion partners in aneurysmal bone cyst and their role in pathogenesis and histopathological evaluation of this disease
IntroductionAneurysmal bone cyst (ABC) belongs to a heterogenous group of reactive and neoplastic processes collectively k...
Molecular profiling of visible polypoid and invisible conventional intestinal-type low-grade dysplasia in patients with idiopathic inflammatory bowel disease
Molecular profiling of visible polypoid and invisible conventional intestinal-type low-grade dysplasia in patients with idiopathic inflammatory bowel disease
Materials and methodsStudy groupsThe study population consisted of four groups of patients identified through a retrospect...
IASLC grading system predicts distant metastases for resected lung adenocarcinoma
IASLC grading system predicts distant metastases for resected lung adenocarcinoma
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Time trends in Gleason score distribution among Gleason score 8 and 9-10 cancers
Time trends in Gleason score distribution among Gleason score 8 and 9-10 cancers
Reporting of prostate cancer grade has drifted to higher reported grades over the past decades. In prostate cancers diagno...
9p24/JAK2 rearrangements in myeloid neoplasms: from myelodysplastic syndromes to myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions
9p24/JAK2 rearrangements in myeloid neoplasms: from myelodysplastic syndromes to myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions
Chromosomal translocations involving 9p24/JAK2 are rare genetic events, typically occurring in B-cell acute lymphoblastic ...
Retraction: Estimation of associations between 10 common gene polymorphisms and gastric cancer: evidence from a meta-analysis
Retraction: Estimation of associations between 10 common gene polymorphisms and gastric cancer: evidence from a meta-analysis
This article1 has been retracted by the Journal of Clinical Pathology due to apparent peer review manipulation.An individu...
My approach to assessing for colorectal polyp cancer
My approach to assessing for colorectal polyp cancer
Assessing a locally excised colorectal adenoma for malignancy is a common but often challenging scenario. This article out...
Systematic literature review of published cases of reactive plasmacytosis in peripheral blood and bone marrow
Systematic literature review of published cases of reactive plasmacytosis in peripheral blood and bone marrow
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Intraductal carcinoma of the prostate: conflicting recommendations confuse clinicians
Intraductal carcinoma of the prostate: conflicting recommendations confuse clinicians
Intraductal carcinoma of the prostate (IDCP) generally represents a growth pattern of invasive aggressive acinar prostate ...
The highs and lows of grading intraductal carcinoma of the prostate
The highs and lows of grading intraductal carcinoma of the prostate
Accurate histological diagnosis and grading are essential for appropriate management of prostate cancer (PCa), yet there r...
Low interobserver agreement among subspecialised breast pathologists in evaluating HER2-low breast cancer
Low interobserver agreement among subspecialised breast pathologists in evaluating HER2-low breast cancer
IntroductionInvasive breast carcinomas with amplification of human epidermal growth factor receptor 2 (ERBB2) gene or over...
SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
WHAT IS ALREADY KNOWN ON THIS TOPICRecent studies have highlighted the effectiveness of epidermal growth factor receptor (...
Tumour-infiltrating lymphocyte subsets and their individual prognostic impact in oral squamous cell carcinoma
Tumour-infiltrating lymphocyte subsets and their individual prognostic impact in oral squamous cell carcinoma
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Unravelling interobserver variability in gastrointestinal glandular neoplasia: a contemporary study of US and Korean pathologists
Unravelling interobserver variability in gastrointestinal glandular neoplasia: a contemporary study of US and Korean pathologists
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Idiopathic granulomatous mastitis: a 5-year retrospective review of cases in a tertiary centre in Dublin, Ireland
Idiopathic granulomatous mastitis: a 5-year retrospective review of cases in a tertiary centre in Dublin, Ireland
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Performance evaluation of a CRISPR Cas9-based selective exponential amplification assay for the detection of KRAS mutations in plasma of patients with advanced pancreatic cancer
Performance evaluation of a CRISPR Cas9-based selective exponential amplification assay for the detection of KRAS mutations in plasma of patients with advanced pancreatic cancer
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Optimal carcinoembryonic antigen (CEA) cutoff values in the diagnosis of neoplastic mucinous pancreatic cysts differ among assays
Optimal carcinoembryonic antigen (CEA) cutoff values in the diagnosis of neoplastic mucinous pancreatic cysts differ among assays
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Rosai-Dorfman Disease of pancreas: rare aetiology mimicking malignancy
Rosai-Dorfman Disease of pancreas: rare aetiology mimicking malignancy
Rosai-Dorfman disease (RDD) is a non-Langerhans cell histiocytosis which usually presents as painless lymphadenopathy. Ext...
Laboratory investigation of peritoneal fluids: an updated practical approach based on the available evidence
Laboratory investigation of peritoneal fluids: an updated practical approach based on the available evidence
Even though analysis of peritoneal fluids (PF) is often requested to medical laboratories for biochemical and morphologica...
Discerning clinicopathological features of congenital neutropenia syndromes: an approach to diagnostically challenging differential diagnoses
Discerning clinicopathological features of congenital neutropenia syndromes: an approach to diagnostically challenging differential diagnoses
Many congenital neutropenic conditions have been defined, but given their rarity, at a combined estimated prevalence of te...
Enteroblastic gastric cancer subtype holds therapeutic clues
Enteroblastic gastric cancer subtype holds therapeutic clues
In this issue of the Journal of Clinical Pathology, Pu and colleagues from the Nanjing University Medical School, China, r...
NTRK gene alterations were enriched in hepatoid or enteroblastic differentiation type of gastric cancer
NTRK gene alterations were enriched in hepatoid or enteroblastic differentiation type of gastric cancer
BackgroundGastric cancer (GC) ranks as the fifth most common cancer and the third-leading cause of cancer-related deaths w...
HER2/ERBB2 overexpression in advanced gallbladder carcinoma: comprehensive evaluation by immunocytochemistry and fluorescence in situ hybridisation on fine-needle aspiration cytology samples
HER2/ERBB2 overexpression in advanced gallbladder carcinoma: comprehensive evaluation by immunocytochemistry and fluorescence in situ hybridisation on fine-needle aspiration cytology samples
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Accuracy and validity of determined cause of death and manner of death following forensic autopsy prosection
Accuracy and validity of determined cause of death and manner of death following forensic autopsy prosection
WHAT IS ALREADY KNOWN ON THIS TOPICCurrently, death certificates are routinely inaccurate, often contain multiple errors a...
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