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The Empty Office: protocol for sequential mixed-method study on the impact of telework activities on social relations and well-being
The Empty Office: protocol for sequential mixed-method study on the impact of telework activities on social relations and well-being
IntroductionToday, there is a great deal of interest in how remote work is changing the labour market and what the consequ...
Characteristics of urinary stone composition among patients with urolithiasis: a retrospective study in China
Characteristics of urinary stone composition among patients with urolithiasis: a retrospective study in China
IntroductionUrolithiasis refers to stones or calculi that occur in the urinary system, such as in the kidneys, ureters, bl...
Nomogram model for predicting medication adherence in patients with various mental disorders based on the Dryad database
Nomogram model for predicting medication adherence in patients with various mental disorders based on the Dryad database
IntroductionPsychiatric disorders represent a formidable challenge to public health. According to a recent report from WHO...
Knowledge, attitudes and practices regarding medication splitting and crushing among the general public in Jordan: a cross-sectional study
Knowledge, attitudes and practices regarding medication splitting and crushing among the general public in Jordan: a cross-sectional study
IntroductionCrushing or splitting oral solid dose forms (OSDFs) is one of the important contemporary debates from the medi...
Understanding the transdiagnostic mechanisms underlying emerging psychopathology in adolescence: study protocol of a 1-year prospective epidemiological (EMERGE) study
Understanding the transdiagnostic mechanisms underlying emerging psychopathology in adolescence: study protocol of a 1-year prospective epidemiological (EMERGE) study
IntroductionRelevance of mental health in adolescenceAdolescent mental health is a major global health issue, with more th...
Effect of goal-directed mobilisation versus standard care on physical functioning among medical inpatients: the GoMob-in randomised, controlled trial
Effect of goal-directed mobilisation versus standard care on physical functioning among medical inpatients: the GoMob-in randomised, controlled trial
IntroductionLow physical activity during hospitalisation is associated with cascading adverse effects, such as falls, depr...
Exploring the lived experiences of deep vein thrombosis patients in Lahore, Pakistan: a qualitative phenomenological study on healthcare challenges, resilience and social support
Exploring the lived experiences of deep vein thrombosis patients in Lahore, Pakistan: a qualitative phenomenological study on healthcare challenges, resilience and social support
STRENGTHS AND LIMITATIONS OF THIS STUDYQualitative interviews helped in extracting a helpful and in-depth understanding of...
Adherence to secondary antibiotic prophylaxis among patients with acute rheumatic fever and/or rheumatic heart disease: a systematic review and meta-analysis
Adherence to secondary antibiotic prophylaxis among patients with acute rheumatic fever and/or rheumatic heart disease: a systematic review and meta-analysis
Strengths and limitations of this studyExtensive searching using the Population Intervention Comparison and Outcome standa...
Factors associated with HPV vaccine acceptance and hesitancy in Africa: a systematic review protocol
Factors associated with HPV vaccine acceptance and hesitancy in Africa: a systematic review protocol
IntroductionHuman papillomavirus (HPV) infection is the most prevalent sexually transmitted infection worldwide.1 It is es...
Analysis of clinical characteristics and risk factors on serrated polyps with synchronous advanced adenoma in elderly and non-elderly people: a retrospective cohort study
Analysis of clinical characteristics and risk factors on serrated polyps with synchronous advanced adenoma in elderly and non-elderly people: a retrospective cohort study
IntroductionColorectal cancer (CRC), which is the third most common global malignancy, is a common malignant tumour threat...
Study protocol: the 'Endoscope CRC cohort, a prospective biobank study on the development and evaluation of diagnostic and prognostic biomarker profiles for colorectal cancer and premalignant lesions
Study protocol: the 'Endoscope CRC cohort, a prospective biobank study on the development and evaluation of diagnostic and prognostic biomarker profiles for colorectal cancer and premalignant lesions
Introduction and rationaleColorectal neoplasiaColorectal cancer (CRC) is the third most common cancer in the world.1 Due t...
Efficacy and safety of electroacupuncture for metabolic dysfunction-associated fatty liver disease: a study protocol for a multicentre, randomised, sham acupuncture-controlled, patient-blinded clinical trial
Efficacy and safety of electroacupuncture for metabolic dysfunction-associated fatty liver disease: a study protocol for a multicentre, randomised, sham acupuncture-controlled, patient-blinded clinical trial
BackgroundMetabolic dysfunction-associated fatty liver disease (MAFLD) is the term suggested in 2020 to replace non-alcoho...
Measurement of climate change-related food (in)security and food sovereignty in Canadas northern communities and the circumpolar region: a scoping review protocol
Measurement of climate change-related food (in)security and food sovereignty in Canadas northern communities and the circumpolar region: a scoping review protocol
IntroductionMultiple voices have called attention to the disparate impact of climate change in the North, in particular, i...
Identifying thresholds for meaningful improvements in NTDT-PRO scores to support conclusions about treatment benefit in clinical studies of patients with non-transfusion-dependent beta-thalassaemia: analysis of pooled data from a phase 2, double-blind, placebo-controlled, randomised trial
Identifying thresholds for meaningful improvements in NTDT-PRO scores to support conclusions about treatment benefit in clinical studies of patients with non-transfusion-dependent beta-thalassaemia: analysis of pooled data from a phase 2, double-blind, placebo-controlled, randomised trial
Statistical analyses were conducted by using SAS V.9.4 or higher (SAS Institute). Analyses were performed using blinded da...
Clinical impact of customised positive airway pressure (PAP) therapy interfaces versus usual care in the treatment of patients with sleep-disordered breathing (3DPiPPIn): a randomised controlled trial protocol
Clinical impact of customised positive airway pressure (PAP) therapy interfaces versus usual care in the treatment of patients with sleep-disordered breathing (3DPiPPIn): a randomised controlled trial protocol
IntroductionSleep-disordered breathing (SDB) is a term encompassing conditions including obstructive sleep apnoea (OSA), c...
Efficacy and safety of remimazolam tosylate for patients undergoing off-pump coronary artery bypass grafting: a study protocol for a non-inferiority randomised controlled trial in China
Efficacy and safety of remimazolam tosylate for patients undergoing off-pump coronary artery bypass grafting: a study protocol for a non-inferiority randomised controlled trial in China
Strengths and limitations of this studyThis is the first non-inferiority trial to investigate haemodynamic fluctuations du...
Coping with cancer pain: a qualitative study to explore pain perception and self-coping strategies of patients with cancer in Sri Lanka
Coping with cancer pain: a qualitative study to explore pain perception and self-coping strategies of patients with cancer in Sri Lanka
STRENGTHS AND LIMITATIONS OF THIS STUDYThe study’s qualitative approach and in-depth exploration of cancer patient’s pain ...
Determinants of underweight among returnee lactating mothers in Gedeb District, Southern Ethiopia: a case-control study
Determinants of underweight among returnee lactating mothers in Gedeb District, Southern Ethiopia: a case-control study
IntroductionMaternal underweight is a condition caused by inadequate dietary intake, poor nutritional absorption or poor b...
Completion and reporting of COVID-19 clinical trials registered on ClinicalTrials.gov during the first 6 months of the pandemic: cohort study
Completion and reporting of COVID-19 clinical trials registered on ClinicalTrials.gov during the first 6 months of the pandemic: cohort study
IntroductionEarly in the COVID-19 pandemic, massive research efforts were mobilised to identify potential treatments for t...
Correcting near vision impairment and womens empowerment: a before-after mixed-methods study among older Zanzibari craftswomen
Correcting near vision impairment and womens empowerment: a before-after mixed-methods study among older Zanzibari craftswomen
STRENGTHS AND LIMITATIONS OF THIS STUDYThe use of mixed-method design provides a comprehensive understanding from the asso...
Registry-based cohort study comparing percentages of patients reaching PASS for knee function outcomes after revision ACLR compared to primary ACLR
Registry-based cohort study comparing percentages of patients reaching PASS for knee function outcomes after revision ACLR compared to primary ACLR
Strengths and limitations of this studyThe large sample size allows assessment of outcomes following anterior cruciate lig...
Parental mental health during preconception years in association with offspring attention deficit hyperactivity disorder (ADHD): a systematic review protocol
Parental mental health during preconception years in association with offspring attention deficit hyperactivity disorder (ADHD): a systematic review protocol
STRENGTHS AND LIMITATIONS OF THIS STUDYOur systematic review is a novel attempt to determine whether parental mental healt...
Animations to communicate public health prevention messages: a realist review protocol
Animations to communicate public health prevention messages: a realist review protocol
The individual, societal and economic costs of preventable ill health and disease are significant, accounting for between ...
Impact of the COVID-19 pandemic on self-paid vaccination intentions for children: a cross-sectional study in China
Impact of the COVID-19 pandemic on self-paid vaccination intentions for children: a cross-sectional study in China
BackgroundAlthough the COVID-19 pandemic is currently under control, it has caused unprecedented impacts including parenta...
Predicting radiotherapy response, Toxicities and quality-of-life related functional outcomes in soft tissue sarcoma of the extremities (PredicT) using dose-volume constraints development: a study protocol
Predicting radiotherapy response, Toxicities and quality-of-life related functional outcomes in soft tissue sarcoma of the extremities (PredicT) using dose-volume constraints development: a study protocol
STRENGTHS AND LIMITATIONS OF THIS STUDYThis is a national study of the prediction of radiotherapy outcomes for patients wi...
Recruitment, retention and reporting of variables related to ethnic diversity in randomised controlled trials: an umbrella review
Recruitment, retention and reporting of variables related to ethnic diversity in randomised controlled trials: an umbrella review
IntroductionRandomised controlled trials (hereafter, trials) are considered the gold standard method to assess the effecti...
Elucidating the dynamics and impact of the gut microbiome on maternal nutritional status during pregnancy, effect on pregnancy outcomes and infant health in rural Pakistan: study protocol for a prospective, longitudinal observational study
Elucidating the dynamics and impact of the gut microbiome on maternal nutritional status during pregnancy, effect on pregnancy outcomes and infant health in rural Pakistan: study protocol for a prospective, longitudinal observational study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe study targets the high fertility age group (17–24) with almost half cohort cons...
Unmet medical needs and influencing factors among Korean police officers: a cross-sectional survey
Unmet medical needs and influencing factors among Korean police officers: a cross-sectional survey
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study examined the unmet medical needs (UMNs) of a relatively large group of p...
Testing a persuasive health communication intervention (PHCI) for emergency department patients who declined rapid HIV/HCV screening: a randomised controlled trial study protocol
Testing a persuasive health communication intervention (PHCI) for emergency department patients who declined rapid HIV/HCV screening: a randomised controlled trial study protocol
IntroductionThe US Centers for Disease Control and Prevention recommends that US emergency departments (EDs) conduct HIV a...
Epidemiology and health care of hyperhidrosis in Germany: claims data analysis
Epidemiology and health care of hyperhidrosis in Germany: claims data analysis
IntroductionHyperhidrosis (HH), a disorder of excessive sweating, is a very distressing condition for which treatment is c...
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