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HIV-1 subtype-specific drug resistance on dolutegravir-based antiretroviral therapy: protocol for a multicentre study (DTG RESIST)
HIV-1 subtype-specific drug resistance on dolutegravir-based antiretroviral therapy: protocol for a multicentre study (DTG RESIST)
STRENGTHS AND LIMITATIONS OF THIS STUDYDTG RESIST is a large international study of dolutegravir resistance in individuals...
The spectrum of acute illness and mortality of children and adolescents presenting to emergency services in Sanghar district hospital, Pakistan: a prospective cohort study
The spectrum of acute illness and mortality of children and adolescents presenting to emergency services in Sanghar district hospital, Pakistan: a prospective cohort study
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study aims to address limited empirical data describing disease burden and mor...
The spectrum of acute illness and mortality of children and adolescents presenting to emergency services in Sanghar district hospital, Pakistan: a prospective cohort study
The spectrum of acute illness and mortality of children and adolescents presenting to emergency services in Sanghar district hospital, Pakistan: a prospective cohort study
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study aims to address limited empirical data describing disease burden and mor...
Cohort profile: The Aboriginal Families Study - a prospective cohort of Aboriginal children and their mothers and caregivers in South Australia
Cohort profile: The Aboriginal Families Study - a prospective cohort of Aboriginal children and their mothers and caregivers in South Australia
IntroductionIn 2007, the Australian Government committed to ‘close the gap in Aboriginal and Torres Strait Islander life e...
Cohort profile: The Aboriginal Families Study - a prospective cohort of Aboriginal children and their mothers and caregivers in South Australia
Cohort profile: The Aboriginal Families Study - a prospective cohort of Aboriginal children and their mothers and caregivers in South Australia
IntroductionIn 2007, the Australian Government committed to ‘close the gap in Aboriginal and Torres Strait Islander life e...
Contemporaneous symptom networks analysis in lymphoma patients during chemotherapy: protocol for a single-centre prospective cross-sectional study
Contemporaneous symptom networks analysis in lymphoma patients during chemotherapy: protocol for a single-centre prospective cross-sectional study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe utilisation of a combination of convenience and purposive sampling enhances the...
Contemporaneous symptom networks analysis in lymphoma patients during chemotherapy: protocol for a single-centre prospective cross-sectional study
Contemporaneous symptom networks analysis in lymphoma patients during chemotherapy: protocol for a single-centre prospective cross-sectional study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe utilisation of a combination of convenience and purposive sampling enhances the...
Acceptability of the use of health related quality of life measurements for decision-making in healthcare science in Vietnam: a qualitative study
Acceptability of the use of health related quality of life measurements for decision-making in healthcare science in Vietnam: a qualitative study
IntroductionAchieving universal health coverage involves ensuring equitable access to healthcare services and healthcare f...
Acceptability of the use of health related quality of life measurements for decision-making in healthcare science in Vietnam: a qualitative study
Acceptability of the use of health related quality of life measurements for decision-making in healthcare science in Vietnam: a qualitative study
IntroductionAchieving universal health coverage involves ensuring equitable access to healthcare services and healthcare f...
Correlation and consistency between resting full-cycle ratio and fractional flow reserve in assessing coronary artery function in a Chinese real-world cohort with non-ST-segment elevation acute coronary syndrome: a retrospective observational study
Correlation and consistency between resting full-cycle ratio and fractional flow reserve in assessing coronary artery function in a Chinese real-world cohort with non-ST-segment elevation acute coronary syndrome: a retrospective observational study
IntroductionFractional flow reserve (FFR) is the gold standard for the functional assessment of the severity of coronary a...
Correlation and consistency between resting full-cycle ratio and fractional flow reserve in assessing coronary artery function in a Chinese real-world cohort with non-ST-segment elevation acute coronary syndrome: a retrospective observational study
Correlation and consistency between resting full-cycle ratio and fractional flow reserve in assessing coronary artery function in a Chinese real-world cohort with non-ST-segment elevation acute coronary syndrome: a retrospective observational study
IntroductionFractional flow reserve (FFR) is the gold standard for the functional assessment of the severity of coronary a...
Frequency of self-directed dying in the Netherlands: research protocol of a cross-sectional mixed-methods study
Frequency of self-directed dying in the Netherlands: research protocol of a cross-sectional mixed-methods study
IntroductionEnd-of-life decision-making and subsequent policymaking are subject of debate worldwide.1 2 Several countries ...
SUPRAMAX-study: supramaximal resection versus maximal resection for glioblastoma patients: study protocol for an international multicentre prospective cohort study (ENCRAM 2201)
SUPRAMAX-study: supramaximal resection versus maximal resection for glioblastoma patients: study protocol for an international multicentre prospective cohort study (ENCRAM 2201)
STRENGTHS AND LIMITATIONS OF THIS STUDYFirst multicentre prospective study directly comparing supramaximal resection (SMR)...
Effect of vitamin D in addition to letrozole on the ovulation rate of women with polycystic ovary syndrome: protocol of a multicentre randomised double-blind controlled trial
Effect of vitamin D in addition to letrozole on the ovulation rate of women with polycystic ovary syndrome: protocol of a multicentre randomised double-blind controlled trial
IntroductionVitamin D regulates calcium and phosphate metabolism in the body. The vitamin D receptor and vitamin D metabol...
Prevalence of modern contraceptive discontinuation and associated factors among married reproductive age group women in Debre Berhan town, Ethiopia: a community-based cross-sectional study
Prevalence of modern contraceptive discontinuation and associated factors among married reproductive age group women in Debre Berhan town, Ethiopia: a community-based cross-sectional study
STRENGTHS AND LIMITATIONS OF THIS STUDYThis study used a small sample size.This study does not represent all women in the ...
Dry cupping as an adjuvant treatment of individuals with severe pneumonia: study protocol for a placebo-controlled, randomised study
Dry cupping as an adjuvant treatment of individuals with severe pneumonia: study protocol for a placebo-controlled, randomised study
STRENGTHS AND LIMITATIONS OF THIS STUDYThe use of dry cupping to assist the treatment of severe pneumonia will not have an...
Navigating duplication in pharmacovigilance databases: a scoping review
Navigating duplication in pharmacovigilance databases: a scoping review
STRENGTHS AND LIMITATIONS OF THIS STUDYThe study involved an extensive literature search on a global scale including both ...
Efficacy and safety of seven Chinese patent medicines combined with conventional triple/quadruple therapy for Helicobacter pylori-positive peptic ulcers: a systematic review and network meta-analysis
Efficacy and safety of seven Chinese patent medicines combined with conventional triple/quadruple therapy for Helicobacter pylori-positive peptic ulcers: a systematic review and network meta-analysis
IntroductionPeptic ulcer disease (PUD) remains a notable health concern, as untreated cases may result in gastroduodenal p...
Cost-effectiveness of methenamine hippurate compared with antibiotic prophylaxis for the management of recurrent urinary tract infections in secondary care: a multicentre, open-label, randomised, non-inferiority trial
Cost-effectiveness of methenamine hippurate compared with antibiotic prophylaxis for the management of recurrent urinary tract infections in secondary care: a multicentre, open-label, randomised, non-inferiority trial
STRENGTHS AND LIMITATIONS OF THIS STUDYData used were collected and analysed following a prespecified health economics ana...
Effect of a national infection control programme in Sweden on prosthetic joint infection incidence following primary total hip arthroplasty: a cohort study
Effect of a national infection control programme in Sweden on prosthetic joint infection incidence following primary total hip arthroplasty: a cohort study
STRENGTHS AND LIMITATIONS OF THIS STUDYLong follow-up time to capture prosthetic joint infection (PJI) events and a very h...
Digital resources in the monitoring of patients with cleft lip and palate: protocol for a scoping review
Digital resources in the monitoring of patients with cleft lip and palate: protocol for a scoping review
STRENGTHS AND LIMITATIONS OF THIS STUDYThis scoping review will provide a comprehensive overview of the evidence related t...
Characteristics of patients who seek medical attention for headache and those who do not: cross-sectional survey and linked medical claims data analysis in Japan
Characteristics of patients who seek medical attention for headache and those who do not: cross-sectional survey and linked medical claims data analysis in Japan
IntroductionHeadache is a prevalent condition worldwide. Epidemiological data from Japan revealed that approximately 36% o...
Financial incentive interventions for smoking cessation among Chinese smokers: study protocol for a cluster randomised controlled trial
Financial incentive interventions for smoking cessation among Chinese smokers: study protocol for a cluster randomised controlled trial
BackgroundTobacco use remains an urgent and critical issue, causing enormous health and economic burdens.1–3 As the world’...
Lifetime costs of alcohol consumption in Thailand: protocol for an incidence-based cost-of-illness study using Markov model
Lifetime costs of alcohol consumption in Thailand: protocol for an incidence-based cost-of-illness study using Markov model
Transitional probabilities of developing alcohol-related diseases/conditionsThe transitional probabilities of developing a...
Liver fat as a dietary target by Chinese Medical Nutrition Therapy (CMNT) diet for treating type 2 diabetes with non-alcoholic fatty liver disease: study protocol for a randomised controlled trial
Liver fat as a dietary target by Chinese Medical Nutrition Therapy (CMNT) diet for treating type 2 diabetes with non-alcoholic fatty liver disease: study protocol for a randomised controlled trial
IntroductionType 2 diabetes and non-alcoholic fatty liver disease (NAFLD) represent a significant global public health con...
COVID-19 vaccine coverage, determinants and inequity amongst refugees and migrants in Pakistan: a cross-sectional study
COVID-19 vaccine coverage, determinants and inequity amongst refugees and migrants in Pakistan: a cross-sectional study
STRENGTHS AND LIMITATIONS OF THIS STUDYThis sampling strategy ensured the representativeness of the population being studi...
Development of a patient decision aid for children and adolescents following anterior cruciate ligament rupture: an international mixed-methods study
Development of a patient decision aid for children and adolescents following anterior cruciate ligament rupture: an international mixed-methods study
Summary of findingsMost adolescents, parents and adults rated all aspects of the decision aid as good-excellent (eg, prese...
Clinician and parent views on urine collection in precontinent children in the UK: a qualitative interview study
Clinician and parent views on urine collection in precontinent children in the UK: a qualitative interview study
STRENGTHS AND LIMITATIONS OF THIS STUDYWe interviewed parents familiar with one or more of the different types of urine co...
Understanding the health system utilisation and reasons for avoidable mortality after fatal injury within a Three-Delays framework in Karonga, Northern Malawi: a retrospective analysis of verbal autopsy data
Understanding the health system utilisation and reasons for avoidable mortality after fatal injury within a Three-Delays framework in Karonga, Northern Malawi: a retrospective analysis of verbal autopsy data
Strengths and limitations of this studyWe have demonstrated the utility of verbal autopsy (VA) for evaluating a health sys...
Outcome measures for children with speech sound disorder: an umbrella review
Outcome measures for children with speech sound disorder: an umbrella review
IntroductionSpeech sound disorder (SSD) is a broad category of speech disorders that involve difficulties in producing and...
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