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SCI Abstract
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ALL
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Effectiveness of mRNA COVID-19 Vaccines as First Booster Doses in England: An Observational Study in OpenSAFELY-TPP
Background: The UK delivered its first “booster” COVID-19 vaccine doses in September 2021, initia
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Associations of Local Cannabis Control Policies With Harmful Cannabis Exposures Reported to the California Poison Control System
Background: Cannabis exposures reported to the California Poison Control System increased followi
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Outdoor Artificial Light at Night and Reproductive Endocrine and Glucose Homeostasis and Polycystic Ovary Syndrome in Women of Reproductive Age
Background: Artificial light at night, a well-recognized circadian clock disrupter, causes distur
Epidemiology
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Defining Spatial Epidemiology: A Systematic Review and Re-orientation
Background: Spatial epidemiology has emerged as an important subfield of epidemiology over the pa
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Strengthening a solid foundation: The role of spatial epidemiology within contemporary epidemiology
From the aDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest School of M...
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Newborn Dried Blood Spot Folate in Relation to Maternal Self-reported Folic Acid Intake, Autism Spectrum Disorder, and Developmental Delay
Background: Maternal folic acid intake has been associated with decreased risk for neurodevelopme
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Comparative Analysis of Instrumental Variables on the Assignment of Buprenorphine/Naloxone or Methadone for the Treatment of Opioid Use Disorder
Background: Instrumental variable (IV) analysis provides an alternative set of identification ass
Epidemiology
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Are Target Trial Emulations the Gold Standard for Observational Studies?: The Authors Respond
To the Editor: We thank Didelez1 for their comments on our recent article.2 We wish it were true tha...
Epidemiology
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It Is Time to Think About Time: The Impact of Secular Trends on Bias Parameter Values from Validation Studies
Quantitative bias analysis is a set of methodologic approaches designed to address systematic sources of error (bias) in e...
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Re. The Role of Cooling Centers in Protecting Vulnerable Individuals from Extreme Heat
Office of Heat Response and Mitigation, City of Phoenix, AZ, School of Geographical Sciences and Urban Planning, Ar...
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Precision and Weighting of Effects Estimated by the Generalized Synthetic Control and Related Methods: The Case of Medicaid Expansion
The study of the impact of Medicaid expansion on cardiovascular disease mortality by Nianogo and colleagues1 in this issue...
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Bias-interpretability Trade-offs in Vaccine Effectiveness Studies Using Test-negative or Cohort Designs
We enjoyed reading the article “Comparison of the test-negative design and cohort design with explicit target trial emulat...
Epidemiology
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Estimated rates of progression to tuberculosis disease for persons infected with Mycobacterium tuberculosis in the United States
Background: In the United States, over 80% of tuberculosis (TB) disease cases are estimated to re
Epidemiology
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Differential Participation, a Potential Cause of Spurious Associations in Observational Cohorts in Environmental Epidemiology
Differential participation in observational cohorts may lead to biased or even reversed estimates. I
Epidemiology
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Leveraging External Validation Data: The Challenges of Transporting Measurement Error Parameters
Approaches to address measurement error frequently rely on validation data to estimate measurement e
Epidemiology
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Re. Emulating a Target Trial of Interventions Initiated During Pregnancy With Healthcare Databases: The Example of COVID-19 Vaccination
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, Cecil G. Sheps Center for...
Epidemiology
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Visualizing External Validity: Graphical Displays to Inform the Extension of Treatment Effects from Trials to Clinical Practice
Background: In the presence of effect measure modification, estimates of treatment effects from r
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Risk Factors and Inequities in Transportation Injury and Mortality in the Canadian Census Health and Environment Cohorts (CanCHECs)
Background: Road traffic injury contributes substantially to morbidity and mortality. Canada stan
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Medicaid Expansion and Racial–Ethnic and Sex Disparities in Cardiovascular Diseases Over 6 Years: A Generalized Synthetic Control Approach
Background: Studies have suggested Medicaid expansion enacted in 2014 has resulted in a reduction
Epidemiology
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Meconium Concentrations of Pesticides and Risk of Hypospadias: A Case–Control Study in Brittany, France
Background: Hypospadias is a male genital tract defect for which an increase in prevalence has be
Epidemiology
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Incorporating Efficacy Data from Initial Trials Into Subsequent Evaluations: Application to Vaccines Against Respiratory Syncytial Virus
Background: When a randomized controlled trial fails to demonstrate statistically significant eff
Epidemiology
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Semiparametric Allocation of Subjects to Cohort Strata
Background: We illustrate a method for stratum assignment in small cohort studies that avoids mod
Epidemiology
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Comparison of the Test-negative Design and Cohort Design With Explicit Target Trial Emulation for Evaluating COVID-19 Vaccine Effectiveness
Background: Observational studies are used for estimating vaccine effectiveness under real-world
Epidemiology
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PROVIDENT: Development and Validation of a Machine Learning Model to Predict Neighborhood-level Overdose Risk in Rhode Island
Background: Drug overdose persists as a leading cause of death in the United States, but resource
Epidemiology
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Distinguishing Immunologic and Behavioral Effects of Vaccination
The interpretation of vaccine efficacy estimands is subtle, even in randomized trials designed to qu
Epidemiology
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Residential Greenness and Long-term Mortality Among Patients Who Underwent Coronary Artery Bypass Graft Surgery
Background: Studies have reported inverse associations between exposure to residential greenness
Epidemiology
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Medications for Opioid Use Disorder and Mortality and Hospitalization Among People With Opioid Use-related Infections
Background: Severe skin and soft tissue infections related to injection drug use have increased i
Epidemiology
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A Mixture of Urinary Phthalate Metabolite Concentrations During Pregnancy and Offspring Social Responsiveness Scale Scores
Background: Phthalates are a group of chemicals with ubiquitous exposure worldwide. Exposures to
Epidemiology
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Validation of the “Indication for Use” (INDO) Variable in the Danish National Prescription Registry
Background: Despite its potential value in register-based pharmacoepidemiologic research, recorde
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Flexible Machine Learning Estimation of Conditional Average Treatment Effects: A Blessing and a Curse
Causal inference from observational data requires untestable identification assumptions. If these as
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