SCI Abstract

search
+
Magnetic resonance imaging of renal oxygenation
Magnetic resonance imaging of renal oxygenation
Renal hypoxia has a key role in the pathophysiology of many kidney diseases. MRI provides surrogate markers of oxygenation...
Dialysis and cognitive impairment
Dialysis and cognitive impairment
People with chronic kidney disease who require maintenance dialysis characteristically experience accelerated and aggravat...
Drivers and mechanisms of cognitive decline in chronic kidney disease
Drivers and mechanisms of cognitive decline in chronic kidney disease
Cognitive impairment is highly prevalent among individuals with chronic kidney disease (CKD). Despite its high prevalence,...
Implantable bioelectronics and wearable sensors for kidney health and disease
Implantable bioelectronics and wearable sensors for kidney health and disease
Established clinical practices for monitoring kidney health and disease — including biopsy and serum biomarker analy...
The effects of sex hormone therapy on kidney function
The effects of sex hormone therapy on kidney function
Progression of chronic kidney disease (CKD) is generally faster in cisgender men than cisgender women, suggesting a protec...
The intelligent podocyte: sensing and responding to a complex microenvironment
The intelligent podocyte: sensing and responding to a complex microenvironment
Podocytes are key components of the glomerular filtration barrier — a specialized structure that is responsible for ...
Chronic kidney disease and dementia: an epidemiological perspective
Chronic kidney disease and dementia: an epidemiological perspective
Ageing populations worldwide face increasing challenges of multimorbidity (that is, the co-occurrence of two or more chron...
Engineered CAR macrophages target kidney inflammation
The administration of anti-inflammatory macrophages has been proposed as an approach to reduce tissue injury in response t...
Treating AAV by targeting T cell responses
Treating AAV by targeting T cell responses
Glucocorticoids are currently used to induce remission in patients with antineutrophil cytoplasmic antibody glomerulonephr...
Bacteria caught in neutrophil and UMOD traps in urine
Bacteria caught in neutrophil and UMOD traps in urine
Several mechanisms prevent the ascent of uropathogenic bacteria from the bladder to the kidney, which can lead to pyelonep...
International expert consensus statement on the diagnosis and management of congenital nephrogenic diabetes insipidus (arginine vasopressin resistance)
International expert consensus statement on the diagnosis and management of congenital nephrogenic diabetes insipidus (arginine vasopressin resistance)
Congenital nephrogenic diabetes insipidus (NDI; also known as arginine vasopressin resistance) is a rare inherited disorde...
A guide to gene–disease relationships in nephrology
A guide to gene–disease relationships in nephrology
The use of next-generation sequencing technologies such as exome and genome sequencing in research and clinical care has t...
ECM remodelling by ADAMTS12 in fibrosis
Fibrosis results from the continuous deposition of extracellular matrix (ECM) by fibroblasts in response to injurious stim...
Kidney disease and reproductive health
Kidney disease and reproductive health
Understanding the relationship between reproductive health and kidney function is important to provide holistic care for p...
Collagen formation, function and role in kidney disease
Collagen formation, function and role in kidney disease
Highly abundant in mammals, collagens define the organization of tissues and participate in cell signalling. Most...
Advancing gender equity to improve kidney care for women: a patient perspective
Women living with kidney disease are exposed to several sex and gender gaps in the clinical practice of standard hemodialy...
Anti-nephrin autoantibodies: a paradigm shift in podocytopathies
Anti-nephrin autoantibodies: a paradigm shift in podocytopathies
A new study demonstrates that anti-nephrin autoantibodies are not merely markers but also actively contribute to the patho...
Drug repurposing for glomerular diseases: an underutilized resource
Drug repurposing for glomerular diseases: an underutilized resource
Drug repurposing in glomerular disease can deliver opportunities for steroid-free regimens, enable personalized multi-targ...
Making advance care planning easier for adults with kidney disease and their clinicians
Advance care planning (ACP) has evolved from a narrow focus on end-of-life preference, such as resuscitation, to a continu...
Lymphocytes and innate immune cells in acute kidney injury and repair
Lymphocytes and innate immune cells in acute kidney injury and repair
Acute kidney injury (AKI) is a common and serious disease entity that affects native kidneys and allografts but for which ...
From improbable to possible: pregnancy with advanced chronic kidney disease
From improbable to possible: pregnancy with advanced chronic kidney disease
Reproductive health is an acknowledged right, yet women with chronic kidney disease (CKD) not only face reduced fertility ...
A focus on kidney ageing
Population ageing will exacerbate the burden of ageing-related diseases, including chronic kidney disease. Mitigating the ...
The global landscape of kidney registries: immense challenges and unique opportunities
The global landscape of kidney registries: immense challenges and unique opportunities
Kidney registries are essential to understanding the burden of kidney disease and facilitating the development of sustaina...
Kidney disease: a global health priority
Kidney disease: a global health priority
The prevalence of kidney disease and its associated morbidity and mortality continue to rise. This crisis cannot be tackle...
Combination therapy for kidney disease in people with diabetes mellitus
Combination therapy for kidney disease in people with diabetes mellitus
Diabetic kidney disease (DKD), defined as co-existing diabetes and chronic kidney disease in the absence of other clear ca...
Chronic kidney disease and the global public health agenda: an international consensus
Chronic kidney disease and the global public health agenda: an international consensus
Early detection is a key strategy to prevent kidney disease, its progression and related complications, but numerous studi...
A new era in the science and care of kidney diseases
A new era in the science and care of kidney diseases
Notable progress in basic, translational and clinical nephrology research has been made over the past five decades. Noneth...
Thiazides in kidney transplant recipients: skin in the game
Thiazides in kidney transplant recipients: skin in the game
Clinical trial data suggest that thiazides and thiazide-like drugs could be beneficial for blood-pressure lowering in pati...
Epithelial cell states associated with kidney and allograft injury
Epithelial cell states associated with kidney and allograft injury
The kidney epithelium, with its intricate arrangement of highly specialized cell types, constitutes the functional core of...
Calcium signalling and transport in the kidney
Calcium signalling and transport in the kidney
The kidney plays a pivotal role in regulating calcium levels within the body. Approximately 98% of the filtered calcium is...
Load More
format_indent_increase