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Let’s get in sync: current standing and future of AI-based detection of patient-ventilator asynchrony
Let’s get in sync: current standing and future of AI-based detection of patient-ventilator asynchrony
Patient-ventilator asynchrony (PVA) is a mismatch between the patient’s respiratory drive/effort and the ventilator ...
Expiratory time constants in mechanically ventilated patients: rethinking the old concept—a narrative review
Expiratory time constants in mechanically ventilated patients: rethinking the old concept—a narrative review
The expiratory time constant (RCEXP) plays an important role in understanding the mechanical properties of the respiratory...
Plasma endostatin at intensive care admission is independently associated with acute kidney injury, dialysis, and mortality in COVID-19
Plasma endostatin at intensive care admission is independently associated with acute kidney injury, dialysis, and mortality in COVID-19
Critical COVID-19 is associated with high mortality, and acute kidney injury (AKI) is common. Endostatin has emerged as a ...
Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study
Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study
The effect of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP) dynamics in patients with acute brain...
Quantification of pulmonary edema using automated lung segmentation on computed tomography in mechanically ventilated patients with acute respiratory distress syndrome
Quantification of pulmonary edema using automated lung segmentation on computed tomography in mechanically ventilated patients with acute respiratory distress syndrome
Quantification of pulmonary edema in patients with acute respiratory distress syndrome (ARDS) by chest computed tomography...
Cellular oxygen consumption in patients with diabetic ketoacidosis
Cellular oxygen consumption in patients with diabetic ketoacidosis
Diabetic ketoacidosis (DKA) is a potentially life-threatening disorder associated with severe alterations in metabolism an...
Lethal versus surviving sepsis phenotypes displayed a partly differential regional expression of neurotransmitters and inflammation and did not modify the blood–brain barrier permeability in female CLP mice
Lethal versus surviving sepsis phenotypes displayed a partly differential regional expression of neurotransmitters and inflammation and did not modify the blood–brain barrier permeability in female CLP mice
Septic encephalopathy is frequent but its pathophysiology is enigmatic. We studied expression of neurotransmitters, inflam...
Mitochondrial DNA in plasma and long-term physical recovery of critically ill patients: an observational study
Mitochondrial DNA in plasma and long-term physical recovery of critically ill patients: an observational study
Post-intensive care syndrome (PICS) poses a notable public health concern, with survivors of critical illness experiencing...
Impact of respiratory cycle during mechanical ventilation on beat-to-beat right ventricle stroke volume estimation by pulmonary artery pulse wave analysis
Impact of respiratory cycle during mechanical ventilation on beat-to-beat right ventricle stroke volume estimation by pulmonary artery pulse wave analysis
The same principle behind pulse wave analysis can be applied on the pulmonary artery (PA) pressure waveform to estimate ri...
Oxygenation and ventilation during prolonged experimental cardiopulmonary resuscitation with either continuous or 30:2 compression-to-ventilation ratios together with 10 cmH20 positive end-expiratory pressure
Oxygenation and ventilation during prolonged experimental cardiopulmonary resuscitation with either continuous or 30:2 compression-to-ventilation ratios together with 10 cmH20 positive end-expiratory pressure
In refractory out-of-hospital cardiac arrest, the patient is commonly transported to hospital with mechanical continuous c...
Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers
Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers
Administration of oxygen therapy is common, yet there is a lack of knowledge on its ability to prevent cellular hypoxia as...
Ineffectiveness of hemoadsorption in large animals with abdominal sepsis: a randomized controlled porcine study
Ineffectiveness of hemoadsorption in large animals with abdominal sepsis: a randomized controlled porcine study
The use of hemoadsorption (HA) has become popular in the treatment of vasoplegic states associated with massive cytokine r...
Pathophysiological implications of ventriculoarterial coupling in septic shock
Pathophysiological implications of ventriculoarterial coupling in septic shock
The left ventricular (LV) ejection phase interaction between the cardiac function and the arterial system is called ventri...
Identifying a target group for selenium supplementation in high-risk cardiac surgery: a secondary analysis of the SUSTAIN CSX trial
Identifying a target group for selenium supplementation in high-risk cardiac surgery: a secondary analysis of the SUSTAIN CSX trial
Recent data from the randomized SUSTAIN CSX trial could not confirm clinical benefits from perioperative selenium treatmen...
Interobserver reliability for manual analysis of sidestream darkfield videomicroscopy clips after resizing in ImageJ
Interobserver reliability for manual analysis of sidestream darkfield videomicroscopy clips after resizing in ImageJ
Direct assessment of microcirculatory function remains a critical care research tool but approaches for analysis of microc...
Robotic-assisted early mobilization and virtual reality: a perspective on innovative support strategies for critically ill patients
Robotic-assisted early mobilization and virtual reality: a perspective on innovative support strategies for critically ill patients
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Circulating endothelial extracellular vesicle signatures correspond with ICU requirement: an exploratory study in COVID-19 patients
Circulating endothelial extracellular vesicle signatures correspond with ICU requirement: an exploratory study in COVID-19 patients
Extracellular vesicles (EVs) represent nanometer-sized, subcellular spheres, that are released from almost any cell type a...
Impact of critical illness on cholesterol and fatty acids: insights into pathophysiology and therapeutic targets
Impact of critical illness on cholesterol and fatty acids: insights into pathophysiology and therapeutic targets
Critical illness is characterized by a hypercatabolic response encompassing endocrine and metabolic alterations. Not only ...
Precision net ultrafiltration dosing in continuous kidney replacement therapy: a practical approach
Precision net ultrafiltration dosing in continuous kidney replacement therapy: a practical approach
Murugan R, Balakumar V, Kerti SJ, Priyanka P, Chang CH, Clermont G, Bellomo R, Palevsky PM, Kellum JA (2018) Net ultrafilt...
Understanding the mechanisms of ventilator-induced lung injury using animal models
Understanding the mechanisms of ventilator-induced lung injury using animal models
Mechanical ventilation is a life-saving therapy in several clinical situations, promoting gas exchange and providing rest ...
Agreement of pCO2 in venous to arterial blood gas conversion models in undifferentiated emergency patients
Agreement of pCO2 in venous to arterial blood gas conversion models in undifferentiated emergency patients
Venous blood gas sampling has replaced arterial sampling in many critically ill patients, though interpretation of venous ...
Ultra-low tidal volume ventilation during cardiopulmonary resuscitation shows no mitigating effect on pulmonary end-organ damage compared to standard ventilation: insights from a porcine model
Ultra-low tidal volume ventilation during cardiopulmonary resuscitation shows no mitigating effect on pulmonary end-organ damage compared to standard ventilation: insights from a porcine model
This study aimed to determine whether ultra-low tidal volume ventilation (ULTVV) applied during cardiopulmonary resuscitat...
Current knowledge gaps in extracorporeal respiratory support
Current knowledge gaps in extracorporeal respiratory support
Extracorporeal life support (ECLS) for acute respiratory failure encompasses veno-venous extracorporeal membrane oxygenati...
Body position to optimize mechanics in ARDS: to which degree does the angle matter?
Body position to optimize mechanics in ARDS: to which degree does the angle matter?
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Protective effect of canagliflozin on post-resuscitation myocardial function in a rat model of cardiac arrest
Protective effect of canagliflozin on post-resuscitation myocardial function in a rat model of cardiac arrest
Currently, most patients with cardiac arrest (CA) show reversible myocardial dysfunction, hemodynamic instability, systemi...
Diaphragm excursions as proxy for tidal volume during spontaneous breathing in invasively ventilated ICU patients
Diaphragm excursions as proxy for tidal volume during spontaneous breathing in invasively ventilated ICU patients
There is a need to monitor tidal volume in critically ill patients with acute respiratory failure, given its relation with...
Extracorporeal cardiopulmonary resuscitation in 2023
Extracorporeal cardiopulmonary resuscitation in 2023
Kennedy JH (1966) The role of assisted circulation in cardiac resuscitation. JAMA 197:615–618Article  CAS  PubMed ...
Continuous chest compressions are associated with higher peak inspiratory pressures when compared to 30:2 in an experimental cardiac arrest model
Continuous chest compressions are associated with higher peak inspiratory pressures when compared to 30:2 in an experimental cardiac arrest model
Ventilation during cardiopulmonary resuscitation (CPR) has long been a part of the standard treatment during cardiac arres...
Hemodynamic effects of supplemental oxygen versus air in simulated blood loss in healthy volunteers: a randomized, controlled, double-blind, crossover trial
Hemodynamic effects of supplemental oxygen versus air in simulated blood loss in healthy volunteers: a randomized, controlled, double-blind, crossover trial
Trauma patients frequently receive supplemental oxygen, but its hemodynamic effects in blood loss are poorly understood. W...
ESICM LIVES 2023
ESICM LIVES 2023
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
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