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Oral corticosteroids for cystic fibrosis pulmonary exacerbation: seeking the future in the past
Oral corticosteroids for cystic fibrosis pulmonary exacerbation: seeking the future in the past
To the Editor:Pulmonary exacerbations remain the most important cause of morbidity, loss of lung function, and reduced qua...
Reply to: Steroids in cystic fibrosis exacerbations: are we picking the right patients?
Reply to: Steroids in cystic fibrosis exacerbations: are we picking the right patients?
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Local receptor-interacting protein kinase 2 inhibition mitigates house dust mite-induced asthma
Local receptor-interacting protein kinase 2 inhibition mitigates house dust mite-induced asthma
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Efficacy and safety of selexipag in patients with inoperable or persistent/recurrent CTEPH (SELECT randomised trial)
Efficacy and safety of selexipag in patients with inoperable or persistent/recurrent CTEPH (SELECT randomised trial)
Graphical abstractOverview of the study. #: patients were stratified by baseline treatment with pulmonary hypertension (PH...
Salivary polyreactive antibodies and Haemophilus influenzae are associated with respiratory infection severity in young children with recurrent respiratory infections
Salivary polyreactive antibodies and Haemophilus influenzae are associated with respiratory infection severity in young children with recurrent respiratory infections
IntroductionRecurrent respiratory tract infections (rRTIs) affect 10–15% of young children [1, 2] and increase the risk of...
Deep phenotyping of unaffected carriers of pathogenic BMPR2 variants screened for pulmonary arterial hypertension
Deep phenotyping of unaffected carriers of pathogenic BMPR2 variants screened for pulmonary arterial hypertension
AbstractIntroduction Pathogenic variants in the gene encoding for BMPR2 are a major genetic risk factor for heritable pulm...
Optimisation of detecting chronic thromboembolic pulmonary hypertension in acute pulmonary embolism survivors: the InShape IV study
Optimisation of detecting chronic thromboembolic pulmonary hypertension in acute pulmonary embolism survivors: the InShape IV study
Conflict of interest: S. Barco received research support from Boston Scientific, Medtronic, Concept Medical, Sanofi and No...
Reply to: Oral corticosteroids for cystic fibrosis pulmonary exacerbation: seeking the future in the past
Reply to: Oral corticosteroids for cystic fibrosis pulmonary exacerbation: seeking the future in the past
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Bronchoconstriction with inhaled ATP in healthy volunteers
Bronchoconstriction with inhaled ATP in healthy volunteers
To the Editor:P2X3 receptors are found on sensory nerves and are activated by ATP. The recent discovery that P2X3 antagoni...
Exacerbation history and blood eosinophil count prior to diagnosis of COPD and risk of subsequent exacerbations
Exacerbation history and blood eosinophil count prior to diagnosis of COPD and risk of subsequent exacerbations
IntroductionReducing the risk of exacerbations is a key objective of COPD management [1] given the substantial evidence ab...
Steroids in cystic fibrosis exacerbations: are we picking the right patients?
Steroids in cystic fibrosis exacerbations: are we picking the right patients?
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What to do when pulmonary arterial hypertension screening suggests neither fish nor fowl? The DOLPHIN-GENESIS study
What to do when pulmonary arterial hypertension screening suggests neither fish nor fowl? The DOLPHIN-GENESIS study
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RIPK2 inhibition gets the NOD for asthma
RIPK2 inhibition gets the NOD for asthma
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Salivary polyreactive antibodies, airway bacteria, and recurrent respiratory infection severity
Salivary polyreactive antibodies, airway bacteria, and recurrent respiratory infection severity
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Selexipag: still looking for its place
Selexipag: still looking for its place
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Previous exacerbations in newly diagnosed COPD patients: do they matter?
Previous exacerbations in newly diagnosed COPD patients: do they matter?
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Reversible carfilzomib-induced pulmonary arterial hypertension: don't take your eyes off the ball!
Reversible carfilzomib-induced pulmonary arterial hypertension: don't take your eyes off the ball!
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A range of 30-62% of functioning multiciliated airway cells is sufficient to maintain ciliary airway clearance
A range of 30-62% of functioning multiciliated airway cells is sufficient to maintain ciliary airway clearance
Graphical AbstractOverview of the study. PCD: primary ciliary dyskinesia; FEV1: forced expiratory volume in 1 s; ODA: oute...
How many functioning ciliated airway epithelial cells are necessary for effective mucociliary clearance?
How many functioning ciliated airway epithelial cells are necessary for effective mucociliary clearance?
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Polysomnographic airflow shapes and site of collapse during drug-induced sleep endoscopy
Polysomnographic airflow shapes and site of collapse during drug-induced sleep endoscopy
AbstractBackground Differences in the pharyngeal site of collapse influence efficacy of non-continuous positive airway pre...
Presenting clinical data for the hazard classification of chemical respiratory sensitisers
Presenting clinical data for the hazard classification of chemical respiratory sensitisers
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Seeing pulmonary hypertension through a paediatric lens: a viewpoint
Seeing pulmonary hypertension through a paediatric lens: a viewpoint
Shareable abstractPaediatric pulmonary hypertension (PH) offers unique genetic and developmental insights that can help in...
The paradox of the safer cigarette: understanding the pulmonary effects of electronic cigarettes
The paradox of the safer cigarette: understanding the pulmonary effects of electronic cigarettes
AbstractElectronic cigarette (e-cigarette) use continues to rise globally. E-cigarettes have been presented as safer alter...
Characteristics and outcomes of patients developing pulmonary hypertension associated with proteasome inhibitors
Characteristics and outcomes of patients developing pulmonary hypertension associated with proteasome inhibitors
French PH Network PULMOTENSION Investigators: Claire Dauphin (Service de Cardiologie et Maladies Vasculaires, Hôpital Gabr...
European Respiratory Society clinical practice guideline on symptom management for adults with serious respiratory illness
European Respiratory Society clinical practice guideline on symptom management for adults with serious respiratory illness
RecommendationWe suggest not using opioids for the treatment of breathlessness in people with serious respiratory illness ...
Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection
Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection
Graphical abstractSummary of the study. Peripheral blood neutrophils from >200 hospitalised patients across three patie...
The effect of high altitude (2500 m) on incremental cycling exercise in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: a randomised controlled crossover trial
The effect of high altitude (2500 m) on incremental cycling exercise in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: a randomised controlled crossover trial
IntroductionIn the absence of predominant lung disease, the major pre-capillary pulmonary hypertension (PH) groups are pul...
Cystic fibrosis in Europe: improved lung function and longevity - reasons for cautious optimism, but challenges remain
Cystic fibrosis in Europe: improved lung function and longevity - reasons for cautious optimism, but challenges remain
ECFSPR Scientific Committee: Andreas Pfleger, Department of Paediatrics and Adolescent Medicine, Division of Paediatric Pu...
Neutrophil elastase-dependent cleavage of LTA4H alters its aminopeptidase activity in cystic fibrosis
Neutrophil elastase-dependent cleavage of LTA4H alters its aminopeptidase activity in cystic fibrosis
To the Editor:The enzyme leukotriene A4 hydrolase (LTA4H) is classically known for its epoxide hydrolase activity that con...
Endotypic traits of supine position and supine-predominant obstructive sleep apnoea in Asian patients
Endotypic traits of supine position and supine-predominant obstructive sleep apnoea in Asian patients
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