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P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study
P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study
PET imaging of activated microglia has improved our understanding of the pathology behind disability progression in MS, an...
Biodistribution and dosimetry of the PET radioligand [18F]CHDI-650 in mice for detection of mutant huntingtin aggregates
Biodistribution and dosimetry of the PET radioligand [18F]CHDI-650 in mice for detection of mutant huntingtin aggregates
Huntington’s disease (HD) is a rare neurodegenerative disorder caused by an expansion of the CAG trinucleotide repea...
Quantitation of mitral regurgitation using positron emission tomography
Quantitation of mitral regurgitation using positron emission tomography
Cardiac positron emission tomography (PET) offers non-invasive assessment of perfusion and left ventricular (LV) function ...
Preclinical evaluation and first-in-human study of [18F]AlF-FAP-NUR for PET imaging cancer-associated fibroblasts
Preclinical evaluation and first-in-human study of [18F]AlF-FAP-NUR for PET imaging cancer-associated fibroblasts
Fibroblast activation protein (FAP) has gained attention as a promising molecular target with potential utility for cancer...
Physiological provocation compared to acetazolamide in the assessment of cerebral hemodynamics: a case report
Physiological provocation compared to acetazolamide in the assessment of cerebral hemodynamics: a case report
Severe large vessel disease may lead to cerebral hemodynamic failure that critically impairs cerebral blood flow (CBF) reg...
Diagnostic and evaluative efficiency of 68Ga-FAPI-04 in skeletal muscle injury
Diagnostic and evaluative efficiency of 68Ga-FAPI-04 in skeletal muscle injury
Skeletal muscles are vital for daily function, yet assessing their injuries remain challenging. We aimed to elucidate the ...
Radiation dosimetry of para-chloro-2-[18F]fluoroethyl-etomidate: a PET tracer for adrenocortical imaging
Radiation dosimetry of para-chloro-2-[18F]fluoroethyl-etomidate: a PET tracer for adrenocortical imaging
[11C]metomidate, a methyl ester analogue of etomidate, is used for positron emission tomography of adrenocortical cancer, ...
Distribution and predictors of F-18-FDG uptake values of non-malignant cervical lymph nodes in pediatric patients
Distribution and predictors of F-18-FDG uptake values of non-malignant cervical lymph nodes in pediatric patients
F-18-flurodeoxyglucose (FDG) PET/CT is routinely used for staging, evaluation of response to treatment and follow-up of mo...
A short 18F-FDG imaging window triple injection neuroimaging protocol for parametric mapping in PET
A short 18F-FDG imaging window triple injection neuroimaging protocol for parametric mapping in PET
In parametric PET, kinetic parameters are extracted from dynamic PET images. It is not commonly used in clinical practice ...
PSMA imaging as a non-invasive tool to monitor inducible gene expression in vivo
PSMA imaging as a non-invasive tool to monitor inducible gene expression in vivo
Das A, Zhou X, Metz SW, Vink MA, Berkhout B. Selecting the optimal Tet-on system for doxycycline-inducible gene expression...
[68 Ga]Ga-FAPI-04 PET/CT may be a predictor for early treatment response in rheumatoid arthritis
[68 Ga]Ga-FAPI-04 PET/CT may be a predictor for early treatment response in rheumatoid arthritis
The identification of biomarkers predicting the treatment response of rheumatoid arthritis (RA) is important. [68&nbsp...
ImmunoPET provides a novel way to visualize the CD103+ tissue-resident memory T cell to predict the response of immune checkpoint inhibitors
ImmunoPET provides a novel way to visualize the CD103+ tissue-resident memory T cell to predict the response of immune checkpoint inhibitors
Immune checkpoint inhibitors (ICIs) have made significant progress in oncotherapy improving survival of patients. However,...
Effects of isoflurane anaesthesia depth and duration on renal function measured with [99mTc]Tc-mercaptoacetyltriglycine SPECT in mice
Effects of isoflurane anaesthesia depth and duration on renal function measured with [99mTc]Tc-mercaptoacetyltriglycine SPECT in mice
The influence of anaesthetic depth and the potential influence of different anaesthetic beds and thus different handling p...
Single time point quantitation of cerebral glucose metabolism by FDG-PET without arterial sampling
Single time point quantitation of cerebral glucose metabolism by FDG-PET without arterial sampling
Until recently, quantitation of the net influx of 2-[18F]fluorodeoxyglucose (FDG) to brain (Ki) and the cerebrometabolic r...
[18F]FDG PET-MR characterization of aortitis in the IL1rn−/− mouse model of giant-cell arteritis
[18F]FDG PET-MR characterization of aortitis in the IL1rn−/− mouse model of giant-cell arteritis
Metabolic imaging is routinely used to demonstrate aortitis in patients with giant-cell arteritis. We aimed to investigate...
Biological efficacy of simulated radiolabeled Lipiodol® ultra-fluid and microspheres for various beta emitters: study based on VX2 tumors
Biological efficacy of simulated radiolabeled Lipiodol® ultra-fluid and microspheres for various beta emitters: study based on VX2 tumors
Radioembolization is one therapeutic option for the treatment of locally early-stage hepatocellular carcinoma. The aim of ...
Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies
Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies
Brain metastases (BM) are the most frequent malignant brain tumors. The aim of this study was to characterize the tumor mi...
Adenosine-induced splenic switch-off on [15O]H2O PET perfusion for the assessment of vascular vasodilatation
Adenosine-induced splenic switch-off on [15O]H2O PET perfusion for the assessment of vascular vasodilatation
Splenic switch-off (SSO) is a marker of adequate adenosine-induced vasodilatation on cardiac magnetic resonance perfusion ...