SCI Abstract

search
+
KLF7 reverses ox-LDL-induced ferroptosis in HMEC-1 cells through transcriptionally activating ALKBH5 to inhibit the m6A modification of ACSL4
KLF7 reverses ox-LDL-induced ferroptosis in HMEC-1 cells through transcriptionally activating ALKBH5 to inhibit the m6A modification of ACSL4
Atherosclerosis is a chronic inflammatory vascular disease. It was confirmed that activation of ferroptosis could induce t...
Effect of combined blue light and 5-ALA on mitochondrial functions and cellular responses in B16F1 melanoma and HaCaT cells
Effect of combined blue light and 5-ALA on mitochondrial functions and cellular responses in B16F1 melanoma and HaCaT cells
In this study, we investigated the effects of blue light and 5-aminolevulinic acid (5-ALA) co-treatment on B16F1 melanoma ...
FOXA1 exacerbates LPS-induced vascular endothelial cell injury in sepsis by suppressing the transcription of NRP2
FOXA1 exacerbates LPS-induced vascular endothelial cell injury in sepsis by suppressing the transcription of NRP2
Endothelial dysfunction plays a critical role in the pathogenesis of sepsis. This study aims to explore the effect and mec...
FEV-mediated WNT2 transcription is involved in the progression of colorectal cancer via the Wnt signaling
FEV-mediated WNT2 transcription is involved in the progression of colorectal cancer via the Wnt signaling
Colorectal cancer (CRC) remains the third leading cause of cancer-related death worldwide. Here, we aimed to uncover the m...
Hydrolyzed cow colostrum extract (BCFM) inhibits alpha-MSH-induced melanogenesis in B16F1 cells via regulation of the MC1R-cAMP signaling pathway
Hydrolyzed cow colostrum extract (BCFM) inhibits alpha-MSH-induced melanogenesis in B16F1 cells via regulation of the MC1R-cAMP signaling pathway
Cow colostrum is the first milk produced after birth and is a rich natural source of nutrients, immunoglobulins, peptides,...
E2F8—TPX2 axis regulates glycolysis and angiogenesis to promote progression and reduce chemosensitivity of liver cancer
E2F8—TPX2 axis regulates glycolysis and angiogenesis to promote progression and reduce chemosensitivity of liver cancer
Liver cancer (LC) is a global health concern, marked by its high prevalence and mortality rates and known for its resistan...
CRISPR-edited, cell-based future-proof meat and seafood to enhance global food security and nutrition
CRISPR-edited, cell-based future-proof meat and seafood to enhance global food security and nutrition
Food security is a major concern due to the growing population and climate change. A method for increasing food production...
Isolation of holostane-type saponins from the black sea cucumber Holothuria atra and evaluating their anti-allergic activity: in vitro and in silico study
Isolation of holostane-type saponins from the black sea cucumber Holothuria atra and evaluating their anti-allergic activity: in vitro and in silico study
Sea cucumbers are both versatile marine organisms and an Asian marine food known to have several medicinal effects. We eva...
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim
MiR-214 promotes the antitumor effect of NK cells in colorectal cancer liver metastasis through USP27X/Bim
Colorectal cancer (CRC) is a common tumor type, and liver metastasis reduces the long-term survival in CRC patients. Natur...
MiR-133 promotes the multidrug resistance of acute myeloid leukemia cells (HL-60/ADR) to daunorubicin
MiR-133 promotes the multidrug resistance of acute myeloid leukemia cells (HL-60/ADR) to daunorubicin
This study aimed to explore the role and molecular mechanism of miR-133 in multidrug resistance in acute myeloid leukemia ...
Engineering Natural Silk
Engineering Natural Silk
This book highlights the potential of silk in a vast array of applications, mainly in the field of medicine, electronics, ...
Heterologous Protein Production in CHO Cells
Heterologous Protein Production in CHO Cells
This book explores the use of Chinese hamster ovary (CHO) cells in the production of therapeutic protein products.
WTAP promotes laryngeal carcinoma cell progression by posttranscriptional activation of CTHRC1 in an m6A-YTHDF1-dependent way
WTAP promotes laryngeal carcinoma cell progression by posttranscriptional activation of CTHRC1 in an m6A-YTHDF1-dependent way
Laryngeal carcinoma is one of the malignancies in the head and neck region with high incidence and mortality. Despite adva...
Conditioned media from human adipose tissue-derived mesenchymal stem cells: potential effect on peripheral blood mononuclear cells in co-culture with HeLa cell line
Conditioned media from human adipose tissue-derived mesenchymal stem cells: potential effect on peripheral blood mononuclear cells in co-culture with HeLa cell line
The use of mesenchymal stem cells (MSCs) for the treatment of various diseases is being investigated, however, their use i...
Up-regulation of LPCAT1 is correlated with poor prognosis and promotes tumor progression in glioblastoma
Up-regulation of LPCAT1 is correlated with poor prognosis and promotes tumor progression in glioblastoma
Glioblastoma (GBM) is a cancer with high malignancy because of its rapid proliferation and high metastatic ability. LPCAT1...
LINC00161 upregulated by M2-like tumor-associated macrophages promotes hepatocellular carcinoma progression by methylating HACE1 promoters
LINC00161 upregulated by M2-like tumor-associated macrophages promotes hepatocellular carcinoma progression by methylating HACE1 promoters
M2-like tumor-associated macrophages (M2-TAM) played an essential part in hepatocellular carcinoma (HCC) progression. Long...
Establishing an evaluation system for T cell activation and anergy based on CD25 expression levels as an indicator
Establishing an evaluation system for T cell activation and anergy based on CD25 expression levels as an indicator
T cell anergy refers to a state where T cells become unresponsive, playing an important role in several types of immune to...
Formation of ovarian organoid by co-culture of human endometrial mesenchymal stem cells and mouse oocyte in 3-dimensional culture system
Formation of ovarian organoid by co-culture of human endometrial mesenchymal stem cells and mouse oocyte in 3-dimensional culture system
The purpose of this study was to compare the formation of organoid structures by co-culturing of human endometrial mesench...
Melatonin enhances therapeutic outcomes of adipose tissue-derived mesenchymal stem cell therapy in rat osteoarthritis by reducing TNF-α and IL-1β-induced injuries
Melatonin enhances therapeutic outcomes of adipose tissue-derived mesenchymal stem cell therapy in rat osteoarthritis by reducing TNF-α and IL-1β-induced injuries
Although adipose tissue-derived mesenchymal stem cell (ADSC) transplantation has been effectively used to treat osteoarthr...
KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation
KIAA1429 promotes the malignancy of oral squamous cell carcinoma by regulating CA9 m6A methylation
KIAA1429 has been reported as a cancer regulator, but its role and mechanism in the progression of oral squamous cell carc...
NEAT1 promotes the progression of prostate cancer by targeting the miR-582-5p/EZH2 regulatory axis
NEAT1 promotes the progression of prostate cancer by targeting the miR-582-5p/EZH2 regulatory axis
In several forms of malignant tumors, nuclear enriched abundant transcript 1 (NEAT1), a lncRNA, has been identified to pla...
Fructobacillus fructosus OS-1010 strain stimulates intestinal cells to secrete exosomes that activate muscle cells
Fructobacillus fructosus OS-1010 strain stimulates intestinal cells to secrete exosomes that activate muscle cells
Fructobacillus is a lactic-acid bacterium recently identified in fructose-rich environments. Fructobacillus is also known ...
Stable two- and three-dimensional cholangiocyte culture systems from extrahepatic bile ducts of biliary atresia patients: use of structural and functional bile duct epithelium models for in vitro analyses
Stable two- and three-dimensional cholangiocyte culture systems from extrahepatic bile ducts of biliary atresia patients: use of structural and functional bile duct epithelium models for in vitro analyses
We herein report two- (2D) and three-dimensional (3D) culture methods of cholangiocytes originating from extrahepatic bile...
The effect of TFAP2A/ANXA8 axis on ferroptosis of cervical squamous cell carcinoma (CESC) in vitro
The effect of TFAP2A/ANXA8 axis on ferroptosis of cervical squamous cell carcinoma (CESC) in vitro
Potential role and associated mechanisms of Annexin A8 (ANXA8), a member of the Annexins family, in cervical squamous cell...
Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling
Pyrroloquinoline quinone protects against murine hepatitis virus strain 3-induced fulminant hepatitis by inhibiting the Keap1/Nrf2 signaling
Fulminant hepatitis (FH) is a life-threatening clinical liver syndrome characterized by substantial hepatocyte necrosis an...
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+ T cell response has been a centr...
miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN
miR-221-3p is upregulated in acute pulmonary embolism complicated with pulmonary hypertension and promotes pulmonary arterial smooth muscle cells proliferation and migration by inhibiting PTEN
Pulmonary arterial smooth muscle cells (PASMCs) functions are associated with the pathogenesis of pulmonary hypertension (...
Gellan gum-gelatin based cardiac models support formation of cellular networks and functional cardiomyocytes
Gellan gum-gelatin based cardiac models support formation of cellular networks and functional cardiomyocytes
Cardiovascular diseases remain as the most common cause of death worldwide. To reveal the underlying mechanisms in varying...
From stem cells to extracellular vesicles: a new horizon in tissue engineering and regenerative medicine
From stem cells to extracellular vesicles: a new horizon in tissue engineering and regenerative medicine
In the fields of tissue engineering and regenerative medicine, extracellular vesicles (EVs) have become viable therapeutic...
Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes
Immature mandarin orange extract increases the amount of hyaluronic acid in human skin fibroblast and keratinocytes
Immature mandarin orange is thinned in order to maturation of orange. To use immature mandarin orange as a cosmetic functi...
Load More
format_indent_increase