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SCI Abstract
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Recent advances in the prevention and treatment of respiratory syncytial virus disease
Respiratory syncytial virus (RSV) is associated with considerable healthcare burden; as such, prevention and treatment of ...
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A high frequency of detection of koala retrovirus fragments in Victorian koalas suggests historic integration of KoRV
Recombinant koala retrovirus (recKoRV) is a recently discovered variant of koala retrovirus (KoRV), which likely emerged d...
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Characterization of human cytomegalovirus infection dynamics in human microglia
Human cytomegalovirus (HCMV) is a β-herpesvirus that establishes asymptomatic infections in immunocompetent individuals bu...
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Temperature affects reptarenavirus growth in a permissive host-derived in vitro model
Reptarenaviruses cause Boid inclusion body disease (BIBD), a lethal disease primarily affecting captive boa constrictors. ...
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Novel endornaviruses infecting Phytophthora cactorum that attenuate vegetative growth, promote sporangia formation and confer hypervirulence to the host oomycete
Two novel endornaviruses were found in Phytophthora cactorum isolated from black lesions on Boehmeria nivea var. nipononiv...
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The impact of pre-existing immunity on the emergence of within-host immune-escape mutations in Omicron lineages
The Omicron variant of SARS-CoV-2 circulating amongst highly immunized populations is anticipated to induce immunological ...
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Development of a loop-mediated isothermal amplification assay for the rapid detection of Alongshan virus
Alongshan virus (ALSV) is a recently discovered tick-borne zoonotic virus. Currently, there is no rapid and accurate clini...
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Functional analysis of BmTsp.C in modulating infection of BmNPV through apoptosis pathways in domestic silkworm (Bombyx mori)
The silkworm, Bombyx mori, is a crucial model insect in agriculture and biological research. Tetraspanins, known for their...
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The identification of a novel interaction site for the human immunodeficiency virus capsid on nucleoporin 153
Human immunodeficiency virus type-1 (HIV-1) can infect non-dividing cells by passing through the selective permeability ba...
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An aegerolysin-like protein from Heliothis virescens ascovirus 3h (HvAV-3h) shows immune suppression and antibacterial activity
Aegerolysins are lipid-binding proteins associated with multiple functions, including membrane pore-formation, insecticida...
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Annual (2024) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)
In April 2024, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly propo...
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Binomial names for virus species: the rediscovery of an old idea
The International Committee on Taxonomy of Viruses now mandates that all virus species names be presented in a binomial fo...
Journal Of General Virology
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Aedes aegypti mosquitoes from Burkina Faso can transmit the chikungunya virus and Zika virus of the African lineage, but not the Zika virus of the Asian lineage
Aedes aegypti is the primary vector for the transmission of dengue virus (DENV), Zika virus (ZIKV), and chikungunya virus ...
Journal Of General Virology
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Spatiotemporal prevalence and characterization of the lineage I insect-specific flavivirus, Quang Binh virus, isolated from Culex gelidus mosquitoes in Singapore
Insect-specific flaviviruses (ISFs) are a group of orthoflaviviruses that can replicate efficiently in arthropods but are ...
Journal Of General Virology
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H5N1 2.3.4.4b: a review of mammalian adaptations and risk of pandemic emergence
Avian influenza viruses can cause severe disease when they spill over into mammalian and human hosts. H5N1 clade 2.3.4.4b ...
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Transmission routes of cluster 3 Tembusu virus in ducks and chickens
Tembusu virus (TMUV) is an emerging mosquito-borne flavivirus, primarily transmitted by Culex spp. mosquitoes. The 2010 ou...
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The saga to monitor and control norovirus: the rise of GII.17
Norovirus is a major cause of acute gastroenteritis in all age groups, with recent surges of cases in Europe and the USA r...
Journal Of General Virology
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Comparative clinical, virological and pathological characterization of equine rotavirus A G3P[12] and G14P[12] infection in neonatal mice
Group A rotavirus (RVA) infections are a leading cause of neonatal diarrhoea in foals. Neonatal mice could serve as a usef...
Journal Of General Virology
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Isolation and genetic characterization of a novel Kevo orbivirus and a strain of Mobuck virus from Ochlerotatus communis mosquitoes in Finland
The genus Orbivirus (Reovirales, Sedoreoviridae) comprises several globally important vector-borne animal viruses, such as...
Journal Of General Virology
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Wisteria floribunda agglutinin enhances Zaire ebolavirus entry through interactions at specific N-linked glycosylation sites on the virus glycoprotein complex
Entry of Zaire ebolavirus (EBOV) into a host cell is a complex process requiring interactions between the viral glycoprote...
Journal Of General Virology
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Squash vein yellowing virus from California emerged in the Middle East via intragenic and intergeneric recombination events in the hypervariable potyvirus P1 and ipomovirus P1a genes
We present the complete sequence of the genomic RNA of an isolate of squash vein yellowing virus (Ipomovirus cucurbitavena...
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Phylogeographic analysis of Begomovirus coat and replication-associated proteins
Begomoviruses are globally distributed plant pathogens that significantly limit crop production. These viruses are traditi...
Journal Of General Virology
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Poxin-deficient poxviruses are sensed by cGAS prior to genome replication
Poxviruses are dsDNA viruses infecting a wide range of cell types, where they need to contend with multiple host antiviral...
Journal Of General Virology
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BALB/c mice challenged with SARS-CoV-2 B.1.351 β variant cause pathophysiological and neurological changes within the lungs and brains
Up to one-third of individuals suffering from acute SARS-CoV-2 infection with the onset of severe-to-mild diseases could d...
Journal Of General Virology
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Organotypic brain slices as a model to study the neurotropism of the highly pathogenic Nipah and Ebola viruses
Nipah virus (NiV) and Ebola virus (EBOV) are highly pathogenic zoonotic viruses with case fatality rates of up to 90%. Whi...
Journal Of General Virology
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ICTV Virus Taxonomy Profile: Peribunyaviridae 2024
Peribunyavirids produce enveloped virions with three negative-sense RNA segments comprising 10.7–12.5 kb in total. The fam...
Journal Of General Virology
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Why is next-generation sequencing essential in modern virology?
A contaminated viral stock results in considerable loss of time, resources and financial means and is generally discovered...
Journal Of General Virology
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Hsp70-Hsp90 organising protein (HOP/STIP1) is required for KSHV lytic replication
Kaposi’s sarcoma-associated herpesvirus (KSHV) is a DNA virus that causes Kaposi’s sarcoma, a cancer of endothelial origin...
Journal Of General Virology
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Preliminary evidence that Bunyamwera virus causes severe disease characterized by systemic vascular and multiorgan necrosis in an immunocompromised mouse model
Bunyamwera virus (BUNV) is the prototypical member of the Bunyamwera serogroup within the Orthobunyvirus genus. BUNV is tr...
Journal Of General Virology
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Vectorial dynamics underpinning current and future tick-borne virus emergence in Europe
Tick-borne diseases pose a growing threat to human and animal health in Europe, with tick-borne encephalitis virus (TBEV) ...
Journal Of General Virology
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