SCI Abstract

search
+
Sotatercept as add-on therapy for advanced PAH
Sotatercept, an activin-signalling inhibitor, is a promising add-on treatment for patients with advanced pulmonary arteria...
Decongestion in heart failure: medical and device therapies
Decongestion in heart failure: medical and device therapies
Heart failure is a leading cause of hospitalization worldwide, and congestion is the predominant cause of heart failure sy...
Redefining respiratory sinus arrhythmia as respiratory heart rate variability: an international Expert Recommendation for terminological clarity
Redefining respiratory sinus arrhythmia as respiratory heart rate variability: an international Expert Recommendation for terminological clarity
The variation of heart rate in phase with breathing, known as ‘respiratory sinus arrhythmia’ (RSA), is a physi...
Social media in modern cardiology: a tool for building community, visibility and impact
Digital communication increasingly shapes early-career cardiology. Social media offers powerful tools for education, netwo...
Endothelial cell metabolism in cardiovascular physiology and disease
Endothelial cell metabolism in cardiovascular physiology and disease
Endothelial cells are multifunctional cells that form the inner layer of blood vessels and have a crucial role in vasoreac...
BMAL1 and HIF2α are key regulators of circadian-dependent variations in myocardial injury
BMAL1 and HIF2α are key regulators of circadian-dependent variations in myocardial injury
A new study published in Nature reveals the role of the interaction between the circadian transcription factor BMAL1 and h...
From data to impact: why conference presentation skills are essential for cardiovascular research dissemination
Conference presentation skills are a crucial, yet often overlooked, element in the dissemination of cardiovascular researc...
Nanomedicine-based strategies for the treatment of vein graft disease
Nanomedicine-based strategies for the treatment of vein graft disease
Autologous saphenous veins are the most frequently used conduits for coronary and peripheral artery bypass grafting. Howev...
Our revered and mysterious heart
Our revered and mysterious heart
A review of Robin Choudhury’s book The Beating Heart: The Art & Science of Our Most Vital Organ, which explo...
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
The skin and cardiovascular systems are connected in unique and meaningful ways, and many diseases conventionally consider...
Improving English proficiency for scientific communication by non-fluent speakers
English has long been the dominant language in scientific communication. Although having a universal language for scientif...
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Debate exists regarding the best terminology for common presentations of heart diseases caused by epicardial and/or microv...
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
After myocardial infarction, monocytes are actively recruited to the brain to augment sleep power and abundance, which in ...
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Heart failure (HF) remains a leading cause of mortality, responsible for 13% of all deaths worldwide. The prognosis for pa...
Cholesterol crystals in the pathogenesis of atherosclerosis
Cholesterol crystals in the pathogenesis of atherosclerosis
The presence of cholesterol crystals (CCs) in tissues was first described more than 100 years ago. CCs have a pathogenic r...
Functional control of myosin motors in the cardiac cycle
Functional control of myosin motors in the cardiac cycle
Contraction of the heart is driven by cyclical interactions between myosin and actin filaments powered by ATP hydrolysis. ...
Cardiac sarcomere turnover by unidirectional replacement of proteins
Cardiac sarcomere turnover by unidirectional replacement of proteins
A new study indicates that proteins in the sarcomere complex are stochastically removed and degraded and are replaced by n...
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
The accessibility of the retina with the use of non-invasive and relatively low-cost ophthalmic imaging techniques and ana...
Reactive oxygen species in hypertension
Reactive oxygen species in hypertension
Hypertension is a leading risk factor for stroke, heart disease and chronic kidney disease. Multiple interacting factors a...
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
In Latin America and the Caribbean (LAC), sociodemographic context, socioeconomic disparities and the high level of urbani...
Potential new therapeutic target for HFpEF
Potential new therapeutic target for HFpEF
A new small-molecule inhibitor of vasohibins reduces myocardial stiffness and improves diastolic relaxation in a rat model...
Stroke triggers an innate immune memory that drives cardiac dysfunction
Stroke triggers an innate immune memory that drives cardiac dysfunction
Acute ischaemic stroke induces persistent innate immune memory through epigenetic changes in myeloid progenitors in the bo...
Mechanisms and treatment of pulmonary arterial hypertension
Mechanisms and treatment of pulmonary arterial hypertension
Substantial progress has been made in the management of pulmonary arterial hypertension (PAH) in the past 25 years, but th...
A newly identified gut hormone suppresses cholesterol production in the liver
A new study identifies a hormone that is secreted by the gut in response to cholesterol absorption and can inhibit cholest...
Small extracellular vesicles from the infarcted heart can promote tumour growth
Small extracellular vesicles from the infarcted heart can promote tumour growth
After myocardial infarction, the heart secretes small extracellular vesicles with pro-neoplastic properties that can accel...
Interventional thrombus modification in STEMI
Interventional thrombus modification in STEMI
In ST-segment elevation myocardial infarction, the role of interventional modification of thrombi in the coronary arteries...
Alain Cribier (1945–2024)
Alain Cribier (1945–2024)
Gilard and Wijns reflect on the life of Alain Cribier, who revolutionized the management of patients with valvular disease.
Uncovering atherosclerotic cardiovascular disease by PET imaging
Uncovering atherosclerotic cardiovascular disease by PET imaging
Assessing atherosclerosis severity is essential for precise patient stratification. Specifically, there is a need to ident...
Canonical and non-canonical roles of complement in atherosclerosis
Canonical and non-canonical roles of complement in atherosclerosis
Cardiovascular diseases are the leading cause of death globally, and atherosclerosis is the major contributor to the devel...
Cardiovascular disease and cancer: shared risk factors and mechanisms
Cardiovascular disease and cancer: shared risk factors and mechanisms
Cardiovascular disease (CVD) and cancer are among the leading causes of morbidity and mortality globally, and these condit...
Load More
format_indent_increase