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Nanomedicine-based strategies for the treatment of vein graft disease
Nanomedicine-based strategies for the treatment of vein graft disease
Autologous saphenous veins are the most frequently used conduits for coronary and peripheral artery bypass grafting. Howev...
Our revered and mysterious heart
Our revered and mysterious heart
A review of Robin Choudhury’s book The Beating Heart: The Art & Science of Our Most Vital Organ, which explo...
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
The skin and cardiovascular systems are connected in unique and meaningful ways, and many diseases conventionally consider...
Improving English proficiency for scientific communication by non-fluent speakers
English has long been the dominant language in scientific communication. Although having a universal language for scientif...
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Debate exists regarding the best terminology for common presentations of heart diseases caused by epicardial and/or microv...
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
After myocardial infarction, monocytes are actively recruited to the brain to augment sleep power and abundance, which in ...
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Heart failure (HF) remains a leading cause of mortality, responsible for 13% of all deaths worldwide. The prognosis for pa...
Cholesterol crystals in the pathogenesis of atherosclerosis
Cholesterol crystals in the pathogenesis of atherosclerosis
The presence of cholesterol crystals (CCs) in tissues was first described more than 100 years ago. CCs have a pathogenic r...
Functional control of myosin motors in the cardiac cycle
Functional control of myosin motors in the cardiac cycle
Contraction of the heart is driven by cyclical interactions between myosin and actin filaments powered by ATP hydrolysis. ...
Cardiac sarcomere turnover by unidirectional replacement of proteins
Cardiac sarcomere turnover by unidirectional replacement of proteins
A new study indicates that proteins in the sarcomere complex are stochastically removed and degraded and are replaced by n...
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
The accessibility of the retina with the use of non-invasive and relatively low-cost ophthalmic imaging techniques and ana...
Reactive oxygen species in hypertension
Reactive oxygen species in hypertension
Hypertension is a leading risk factor for stroke, heart disease and chronic kidney disease. Multiple interacting factors a...
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
In Latin America and the Caribbean (LAC), sociodemographic context, socioeconomic disparities and the high level of urbani...
Potential new therapeutic target for HFpEF
Potential new therapeutic target for HFpEF
A new small-molecule inhibitor of vasohibins reduces myocardial stiffness and improves diastolic relaxation in a rat model...
Stroke triggers an innate immune memory that drives cardiac dysfunction
Stroke triggers an innate immune memory that drives cardiac dysfunction
Acute ischaemic stroke induces persistent innate immune memory through epigenetic changes in myeloid progenitors in the bo...
Mechanisms and treatment of pulmonary arterial hypertension
Mechanisms and treatment of pulmonary arterial hypertension
Substantial progress has been made in the management of pulmonary arterial hypertension (PAH) in the past 25 years, but th...
A newly identified gut hormone suppresses cholesterol production in the liver
A new study identifies a hormone that is secreted by the gut in response to cholesterol absorption and can inhibit cholest...
Small extracellular vesicles from the infarcted heart can promote tumour growth
Small extracellular vesicles from the infarcted heart can promote tumour growth
After myocardial infarction, the heart secretes small extracellular vesicles with pro-neoplastic properties that can accel...
Interventional thrombus modification in STEMI
Interventional thrombus modification in STEMI
In ST-segment elevation myocardial infarction, the role of interventional modification of thrombi in the coronary arteries...
Alain Cribier (1945–2024)
Alain Cribier (1945–2024)
Gilard and Wijns reflect on the life of Alain Cribier, who revolutionized the management of patients with valvular disease.
Uncovering atherosclerotic cardiovascular disease by PET imaging
Uncovering atherosclerotic cardiovascular disease by PET imaging
Assessing atherosclerosis severity is essential for precise patient stratification. Specifically, there is a need to ident...
Canonical and non-canonical roles of complement in atherosclerosis
Canonical and non-canonical roles of complement in atherosclerosis
Cardiovascular diseases are the leading cause of death globally, and atherosclerosis is the major contributor to the devel...
Cardiovascular disease and cancer: shared risk factors and mechanisms
Cardiovascular disease and cancer: shared risk factors and mechanisms
Cardiovascular disease (CVD) and cancer are among the leading causes of morbidity and mortality globally, and these condit...
Gut bacteria can break down cholesterol
Gut bacteria can break down cholesterol
A new study identifies a group of gut bacteria that can metabolize cholesterol and are associated with lower plasma choles...
Clonal expansion of CD8+ T cells in aged mice linked to pro-atherogenic phenotype
In aged mice, but not young mice, with atherosclerosis, depletion of CD8+ T cells significantly reduces atherosclerotic le...
Levothyroxine supplementation does not improve heart transplantation from brain-dead donors
The use of intravenous levothyroxine does not increase the likelihood of hearts being transplanted from haemodynamically u...
Mosaic loss of chromosome Y and cardiovascular disease
Mosaic loss of chromosome Y and cardiovascular disease
Mosaic loss of chromosome Y (mLOY) refers to the condition in male individuals in which a detectable fraction of cells los...
Anticoagulation in patients with atrial high-rate episodes
Anticoagulation in patients with atrial high-rate episodes
The risk of stroke in patients with atrial high-rate episodes (AHREs) depends on age, comorbidities and AHRE burden. Two r...
Not a spectator sport: improving participation of Black patients in cardiovascular clinical trials
Representation of Black patients in cardiovascular clinical trials remains dismally low, reflective of systemic and struct...
Author Correction: Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction
Department of Cardiology, Maria Cecilia Hospital, GVM Care & Research, Cotignola, ItalyMattia GalliDepartment of Cardi...
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