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SCI Abstract
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ALL
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Targeting anti-PAD4 autoantibodies in RA
Findings implicate anti-PAD4 antibodies in the pathogenesis of rheumatoid arthritis.
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Arterial and venous thrombosis in systemic and monogenic vasculitis
Systemic vasculitis, common forms of which include anti-neutrophil cytoplasmic antibody-associated small-vessel vasculitis...
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Understanding rheumatic disease through continuous cell state analysis
Autoimmune rheumatic diseases are a heterogeneous group of conditions, including rheumatoid arthritis (RA) and systemic lu...
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Region-specific, data-driven guidelines are needed for rheumatic diseases in LMICs
Separate guidelines are needed for the management and diagnosis of rheumatic diseases in low- and middle-income countries,...
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The pathogenesis, clinical presentations and treatment of monogenic systemic vasculitis
Many monogenic autoinflammatory diseases, including DADA2 (deficiency of adenosine deaminase 2), HA20 (haploinsufficiency ...
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Fibroblasts in immune responses, inflammatory diseases and therapeutic implications
Once regarded as passive bystander cells of the tissue stroma, fibroblasts have emerged as active orchestrators of tissue ...
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How JAK inhibitors tip the prothrombotic balance in rheumatoid arthritis
The increased incidence of deep vein thromboses and pulmonary emboli has long been noted in rheumatoid arthritis and has b...
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Insights into Lyme arthritis
Two complimentary studies provide a deeper understanding of Lyme disease and the associated chronic complications, such as...
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Risk of uveitis in SpA is changing
Findings from an observational study suggest that the frequency of uveitis in patients with spondyloarthritis has declined...
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Rheumatology in the digital health era: status quo and quo vadis?
Rheumatology faces a critical shortage of health-care professionals, exacerbated by an ageing patient population and escal...
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Novel autoantigen in idiopathic lung disease
The presence of anti-IFI16 autoantibodies in patients with idiopathic interstitial pneumonia is linked to poor prognosis a...
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Dupuytren contracture treatments compared
In an open-label clinical trial, collagenase injection was not noninferior to limited fasciectomy for the treatment of Dup...
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The management of adult and paediatric uveitis for rheumatologists
Uveitis encompasses multiple different conditions that are all characterized by intra-ocular inflammation. Uveitis occurs ...
Nature Reviews Rheumatology
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The essential roles of memory B cells in the pathogenesis of systemic lupus erythematosus
Emerging evidence indicates that memory B cells are dysfunctional in systemic lupus erythematosus (SLE). They are hyporesp...
Nature Reviews Rheumatology
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Publisher Correction: Recent advances in the diagnosis and management of neuropsychiatric lupus
Authors and AffiliationsDivision of Rheumatology, Department of Medicine, Dalhousie University and Queen Elizabeth II Heal...
Nature Reviews Rheumatology
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The emergence of SLE-causing UNC93B1 variants in 2024
During the past year, four studies have reported ten mutations in UNC93B1, which encodes the Toll-like receptor (TLR) chap...
Nature Reviews Rheumatology
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Advancements and challenges in CAR T cell therapy in autoimmune diseases
Chimeric antigen receptor (CAR) T cells are highly effective at targeting and eliminating cells of the B cell lineage. CAR...
Nature Reviews Rheumatology
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The past 25 years in paediatric rheumatology: insights from monogenic diseases
The past 25 years have seen major novel developments in the field of paediatric rheumatology. The concept of autoinflammat...
Nature Reviews Rheumatology
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The role of obesity and adipose tissue dysfunction in osteoarthritis pain
Obesity has a pivotal and multifaceted role in pain associated with osteoarthritis (OA), extending beyond the mechanistic ...
Nature Reviews Rheumatology
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Behavioural therapy app for fibromyalgia
Cognitive behavioural therapy, including acceptance and commitment therapy (ACT), is recommended as part of a multimodal a...
Nature Reviews Rheumatology
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Ion channels in osteoarthritis: emerging roles and potential targets
Osteoarthritis (OA) is a highly prevalent joint disease that causes substantial disability, yet effective approaches to di...
Nature Reviews Rheumatology
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PDZK1 downregulation linked to mitochondrial dysfunction in OA
The PDZ domain-containing scaffold protein PDZK1 is downregulated in osteoarthritic chondrocytes and is linked to mitochon...
Nature Reviews Rheumatology
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Advancing equity in genomic medicine for rheumatology
Increasing diversity in genomic studies is essential to advance precision medicine and health equity in rheumatic diseases...
Nature Reviews Rheumatology
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Macrophage-coated nanocarriers for gouty arthritis
In a new study, researchers use M2 macrophage exosomes and membranes to disguise a tri-drug-carrying nanosystem that reduc...
Nature Reviews Rheumatology
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Author Correction: International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening: an International Myositis Assessment and Clinical Studies Group (IMACS) initiative
National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, ...
Nature Reviews Rheumatology
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Author Correction: Proposals for the rheumatological use of JAK inhibitors
Authors and AffiliationsUniversity della Campania, Department of Precision Medicine, Naples, ItalyFrancesco CicciaUniversi...
Nature Reviews Rheumatology
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Time for a new approach to drug development for rare systemic autoinflammatory diseases
Despite the transformative potential of treatments for systemic autoinflammatory diseases, these conditions remain underfu...
Nature Reviews Rheumatology
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Author Correction: Therapeutic potential in rheumatic diseases of extracellular vesicles derived from mesenchymal stromal cells
Author notesThese authors contributed equally: Christian Jorgensen, Danièle Noël.Authors and AffiliationsIRMB, University ...
Nature Reviews Rheumatology
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Benralizumab noninferior to mepolizumab for EGPA
In a head-to-head phase III trial of two drugs that target IL-5 or its receptor, benralizumab was noninferior to mepolizum...
Nature Reviews Rheumatology
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Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis
In rheumatoid arthritis, juvenile idiopathic arthritis and other forms of inflammatory arthritis, the immune system target...
Nature Reviews Rheumatology
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