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Primary intracranial sarcoma associated with mutant: a case report and preclinical investigation
Primary intracranial sarcoma associated with mutant: a case report and preclinical investigation
Primary intracranial sarcoma (PIS) is a rare and aggressive pediatric brain tumor, which is partially associated with DICE...
Progression of long-term “untreated” oligodendroglioma cases: possible contribution of genomic instability
Progression of long-term “untreated” oligodendroglioma cases: possible contribution of genomic instability
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu ...
Visualizing the endothelial glycocalyx in human glioma vasculature
Visualizing the endothelial glycocalyx in human glioma vasculature
Gliomas are the most common primary brain tumors in adults. However, glioblastoma is especially difficult to treat despite...
CLINICAL utility of assessing status in recurrent astrocytomas
CLINICAL utility of assessing status in recurrent astrocytomas
IDH-mutant astrocytomas exhibit a more indolent natural history and better prognosis compared to their IDH-wild type count...
Discordant lymphoma characterized by the coexistence of diffuse large B-cell lymphoma in the brain and mantle cell lymphoma in the colon, rectum, and bone marrow
Discordant lymphoma characterized by the coexistence of diffuse large B-cell lymphoma in the brain and mantle cell lymphoma in the colon, rectum, and bone marrow
We describe a rare case of discordant lymphoma characterized by the coexistence of diffuse large B-cell lymphoma (DLBCL) i...
Analysis of clinical, histological, and genomic information of molecular glioblastoma in a Japanese glioma cohort
Analysis of clinical, histological, and genomic information of molecular glioblastoma in a Japanese glioma cohort
In the 2021 WHO Central Nervous System tumor classification, the “Glioblastoma, IDH-wildtype” diagnosis change...
The function of chaperones in the radioresistance of glioblastoma: a new insight into the current knowledge
The function of chaperones in the radioresistance of glioblastoma: a new insight into the current knowledge
Radiotherapy remains a cornerstone of brain tumor treatment; however, its effectiveness is frequently undermined by the de...
Rapidly progressive scalp and lung metastases with fatal pneumothorax in glioblastoma, IDH-wildtype, with and amplifications: a case report of clinical course and postmortem autopsy, including genetic analysis
Rapidly progressive scalp and lung metastases with fatal pneumothorax in glioblastoma, IDH-wildtype, with and amplifications: a case report of clinical course and postmortem autopsy, including genetic analysis
We report a rare case of extracranial metastases of a glioblastoma, IDH-wildtype, in a 77-year-old man who initially prese...
Intraspinal rearranged tumor with nerve differentiation
Intraspinal rearranged tumor with nerve differentiation
The ASPSCR1::TFE3 rearrangement has been described in alveolar soft part sarcoma, MiT family translocation renal cell carc...
Triple sellar collision lesion: a unique case of pituitary adenoma, Rathke cleft cyst, and xanthogranuloma—case report and systematic review of the literature
Triple sellar collision lesion: a unique case of pituitary adenoma, Rathke cleft cyst, and xanthogranuloma—case report and systematic review of the literature
The coexistence of three lesions in the sellar region is exceedingly rare. Only two cases with three histopathologically d...
Targeting TGF-β signaling in glioblastoma: therapeutic implications and novel drug development strategies
Targeting TGF-β signaling in glioblastoma: therapeutic implications and novel drug development strategies
Glioma, a prevalent primary brain tumor, arises from the supporting cells of the central nervous system (CNS) and is categ...
Primary pigmented papillary epithelial tumor of the sella: case report and literature review
Primary pigmented papillary epithelial tumor of the sella: case report and literature review
Primary pigmented papillary epithelial tumor of the sella (PPPET) is a recently identified tumor entity that commonly orig...
Comprehensive molecular characterization of craniopharyngiomas using whole transcriptome and spatial transcriptomics approaches
Comprehensive molecular characterization of craniopharyngiomas using whole transcriptome and spatial transcriptomics approaches
Craniopharyngiomas (CPs) are rare benign brain tumors that are classified as WHO grade I, with two subtypes: adamantinomat...
Integrated analysis of MYC expression, 8q24.21 copy number, and recurrence patterns in astrocytoma, IDH-mutant
Integrated analysis of MYC expression, 8q24.21 copy number, and recurrence patterns in astrocytoma, IDH-mutant
Compared to oligodendrogliomas, astrocytomas may have a relatively higher frequency of intracranial remote recurrence, des...
Activated astrocytes drive the accumulation of apolipoprotein E at the brain tumor edge
Activated astrocytes drive the accumulation of apolipoprotein E at the brain tumor edge
While tumor-associated macrophages (TAMs) have been extensively studied, the role of tumor-associated astrocytes (TAAs) in...
Association between autologous formalin-fixed tumor vaccine (AFTV) therapy, molecular pathological markers, and survival outcomes in glioblastoma
Association between autologous formalin-fixed tumor vaccine (AFTV) therapy, molecular pathological markers, and survival outcomes in glioblastoma
Glioblastoma (GBM) is a primary brain tumor, characterized by rapid progression, high recurrence rates, and resistance to ...
How is rosette formation in brain tumours linked with cerebrospinal fluid spread?
How is rosette formation in brain tumours linked with cerebrospinal fluid spread?
Rosette formation, a characteristic histopathological feature of various paediatric brain tumours, appears to be linked wi...
Preface
Preface
The 42nd Japanese Society of Brain Tumor Pathology.The 42nd Annual Meeting of the Ja...
A case of primary papillary epithelial tumor of the sella with reverse polarity and paired box 8 expression
A case of primary papillary epithelial tumor of the sella with reverse polarity and paired box 8 expression
Primary papillary epithelial tumor of the sella (PPETS) is a rare sellar neoplasm characterized by distinctive papillary a...
Tectal glioma: clinical, radiological, and pathological features, and the importance of molecular analysis
Tectal glioma: clinical, radiological, and pathological features, and the importance of molecular analysis
Tectal glioma (TG) is a rare lower grade glioma (LrGG) that occurs in the tectum, mainly affecting children. TG shares pat...
Primary papillary epithelial tumor of the sella: a case report of an emerging tumor type
Primary papillary epithelial tumor of the sella: a case report of an emerging tumor type
Primary papillary epithelial tumor of the sella (PPETS) is a newly described tumor entity with prototypical location in th...
Development of a rapid and comprehensive genomic profiling test supporting diagnosis and research for gliomas
Development of a rapid and comprehensive genomic profiling test supporting diagnosis and research for gliomas
A prompt and reliable molecular diagnosis for brain tumors has become crucial in precision medicine. While Comprehensive G...
Rise of oligodendroglioma hypermutator phenotype from a subclone harboring TP53 mutation after TMZ treatment
Rise of oligodendroglioma hypermutator phenotype from a subclone harboring TP53 mutation after TMZ treatment
Oligodendrogliomas characterized and defined by 1p/19q co-deletion are slowly growing tumors showing better prognosis than...
Intratumoral heterogeneity of CDKN2A deletions in IDH-mutant astrocytoma
Intratumoral heterogeneity of CDKN2A deletions in IDH-mutant astrocytoma
Broggi G, Barresi V (2023) Assessment of CDKN2A/B homozygous deletion in gliomas: to FISH or not to FISH? J Neuropathol Ex...
Oligodendroglioma, IDH-mutant and 1p/19q-codeleted-prognostic factors, standard of care and chemotherapy, and future perspectives with neoadjuvant strategy
Oligodendroglioma, IDH-mutant and 1p/19q-codeleted-prognostic factors, standard of care and chemotherapy, and future perspectives with neoadjuvant strategy
Oligodendroglioma, IDH-mutant and 1p/19q-codeleted is known for their relative chemosensitivity and indolent clinical cour...
Comprehensive genomic analysis reveals clonal origin and subtype-specific evolution in a case of sporadic multiple meningiomas
Comprehensive genomic analysis reveals clonal origin and subtype-specific evolution in a case of sporadic multiple meningiomas
Meningioma is the most common primary intracranial tumor in adults, with up to 10% manifesting as multiple tumors. Data on...
MAPK pathway alterations in polymorphous low-grade neuroepithelial tumor of the young: diagnostic considerations
MAPK pathway alterations in polymorphous low-grade neuroepithelial tumor of the young: diagnostic considerations
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently recognised tumor type with indolent behavi...
Comparative analyses of immune cells and alpha-smooth muscle actin-positive cells under the immunological microenvironment between with and without dense fibrosis in primary central nervous system lymphoma
Comparative analyses of immune cells and alpha-smooth muscle actin-positive cells under the immunological microenvironment between with and without dense fibrosis in primary central nervous system lymphoma
Histopathologic examinations of primary central nervous system lymphoma (PCNSL) reveal concentric accumulation of lymphocy...
Double-hit primary central nervous system lymphoma with histogenetically proven bone marrow infiltration: a case report and a review of the literature
Double-hit primary central nervous system lymphoma with histogenetically proven bone marrow infiltration: a case report and a review of the literature
Double-hit lymphoma (DHL) formerly referred to high-grade B-cell lymphoma with concurrent MYC and BCL2 or BCL6 rearrangeme...
Novel case of ependymoma-like tumor with mesenchymal differentiation harboring ZFTA::RELA fusion in an adult
Novel case of ependymoma-like tumor with mesenchymal differentiation harboring ZFTA::RELA fusion in an adult
High-grade supratentorial tumors harboring ZFTA::NCOA1/2 fusion in infants presenting with mixed histology of embryonal-ap...
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