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Oscillatory Dynamics Serving Verbal Working Memory Differ in People with HIV and Are Linked To Disease Duration
Oscillatory Dynamics Serving Verbal Working Memory Differ in People with HIV and Are Linked To Disease Duration
Medical advances have greatly improved the quality of life and extended the longevity of people with HIV (PWH). However, m...
Telitacicept Inhibits the Maturation and Differentiation of B Lymphocytes in NMOSD
Telitacicept Inhibits the Maturation and Differentiation of B Lymphocytes in NMOSD
Telitacicept, a novel recombinant fusion protein comprising the ligand-binding domain of the TACI receptor and the Fc comp...
Emerging Role of Oligodendrocytes Malfunction in the Progression of Alzheimer's Disease
Emerging Role of Oligodendrocytes Malfunction in the Progression of Alzheimer's Disease
Alzheimer’s disease (AD), the most prevalent form of dementia, is characterized by hallmark pathologies such as amyl...
Rutin Attenuates Virus Entry and Replication and Exerts Neuroprotection in Experimental Models of Japanese Encephalitis
Rutin Attenuates Virus Entry and Replication and Exerts Neuroprotection in Experimental Models of Japanese Encephalitis
Japanese encephalitis virus (JEV), which belongs to the virus family of Flaviviridae, is a threat to more than three billi...
Comparative Study on the Neuroprotective Effects of Perindopril and Benazepril in Experimentally-induced Chronic Mild Stress in Rats
Comparative Study on the Neuroprotective Effects of Perindopril and Benazepril in Experimentally-induced Chronic Mild Stress in Rats
Depression remains a major global health issue, characterized by inadequate response rates to conventional antidepressant ...
Sinomenine Hydrochloride Impedes Memory Impairments via Nrf2/HO-1-Mediated Inhibition of Oxidative Stress, Neuroinflammation and Apoptosis in Mice Brain
Sinomenine Hydrochloride Impedes Memory Impairments via Nrf2/HO-1-Mediated Inhibition of Oxidative Stress, Neuroinflammation and Apoptosis in Mice Brain
Oxidative stress is a key factor in the progression of Alzheimer’s disease (AD) and other neurodegenerative disorder...
Cytokine Blockade Attenuates Inflammation and Improves Depressive Psychopathology After COVID-19: A Naturalistic Observational Study
Cytokine Blockade Attenuates Inflammation and Improves Depressive Psychopathology After COVID-19: A Naturalistic Observational Study
Current insight on inflammation in psychiatry suggests that perturbation of inflammatory set points could foster psychopat...
TNF-α Inhibition Modulates CX3CR1, Pyroptosis-related Genes, and BDNF to Alleviate Anxiety-like Behavior in Type 2 Diabetic Rats
TNF-α Inhibition Modulates CX3CR1, Pyroptosis-related Genes, and BDNF to Alleviate Anxiety-like Behavior in Type 2 Diabetic Rats
Type 2 diabetes is strongly associated with neuroinflammation and neurodegeneration in the hippocampus, yet the underlying...
Differential Effects of Cannabinoid Receptor 2 Agonists on HIV Replication and Inflammatory Activation in Monocyte-Derived Macrophages and Induced Pluripotent Stem Cell-Derived Microglia
Differential Effects of Cannabinoid Receptor 2 Agonists on HIV Replication and Inflammatory Activation in Monocyte-Derived Macrophages and Induced Pluripotent Stem Cell-Derived Microglia
Emerging evidence suggests brain-resident myeloid cells, including perivascular macrophages and microglia, provide a reser...
The Identification and Synthesis of New Sea Cucumber Peptides Leveraging Peptidomics Technology, along with their Anti-Parkinson’s Disease Efficacy
The Identification and Synthesis of New Sea Cucumber Peptides Leveraging Peptidomics Technology, along with their Anti-Parkinson’s Disease Efficacy
Parkinson’s disease (PD), the second most prevalent neurodegenerative disorder, remains without a curative pharmacol...
S-Ketamine Alleviates Anxiety-Induced Chronic Postoperative Pain by Affecting Glucose Metabolism of Striatal Microglia in a Rat Model
S-Ketamine Alleviates Anxiety-Induced Chronic Postoperative Pain by Affecting Glucose Metabolism of Striatal Microglia in a Rat Model
Patients admitted for surgery commonly experience preoperative anxiety. Previous studies have shown that preoperative anxi...
Neurological Adverse Events from COVID-19 Vaccination and It’s Associated Factors in Burkina Faso: Analysis of Spontaneous Reports from the National Database of Pharmacovigilance from 2021 to 2023
Neurological Adverse Events from COVID-19 Vaccination and It’s Associated Factors in Burkina Faso: Analysis of Spontaneous Reports from the National Database of Pharmacovigilance from 2021 to 2023
Neurological adverse effects are frequent, primarily non-serious, due to the tropism of COVID 19 adverse effects for neuro...
Lipid-Metabolically Active TREM2 Microglia‑Derived Macrophages Predict Poor Prognosis and Represent an Immunotherapeutic Target in Glioma
Lipid-Metabolically Active TREM2 Microglia‑Derived Macrophages Predict Poor Prognosis and Represent an Immunotherapeutic Target in Glioma
Gliomas are the most common primary brain tumors and characterized by poor prognosis and heavy infiltration of tumor-assoc...
Differential Roles of Neuro-Inflammatory Regulator, MAPK11 in Cortex and Hippocampus Following Post-Stroke Cognitive Impairments in Rats
Differential Roles of Neuro-Inflammatory Regulator, MAPK11 in Cortex and Hippocampus Following Post-Stroke Cognitive Impairments in Rats
Ischaemic stroke is the leading cause of long-term cognitive impairments, affecting brain regions vulnerable to memory and...
Pyrimidine Derivative, (E)-N-[4-(4-Chlorophenyl)-6-(4-Methylphenyl)Pyrimidin-2-yl]-1-(Furan-2-yl)Methanimine, Named BN5 Ameliorates Cognitive Dysfunction and Regulates and Expression in Female In Vivo Zebrafish Alzheimer Model
Pyrimidine Derivative, (E)-N-[4-(4-Chlorophenyl)-6-(4-Methylphenyl)Pyrimidin-2-yl]-1-(Furan-2-yl)Methanimine, Named BN5 Ameliorates Cognitive Dysfunction and Regulates and Expression in Female In Vivo Zebrafish Alzheimer Model
Alzheimer’s disease (AD) is the most common form of dementia, characterized by a progressive decline in cognitive fu...
Inhibition of TRAF3IP2 Modulates NAMPT and NAD Metabolism in Glioblastoma
Inhibition of TRAF3IP2 Modulates NAMPT and NAD Metabolism in Glioblastoma
Glioblastoma is a grade 4 diffuse astrocytic glioma that is the most aggressive brain malignancy, with poor treatment outc...
Gut Microbiota Dysbiosis and Neuroimmune Alterations in a Postmenopausal-Stress Rat Model
Gut Microbiota Dysbiosis and Neuroimmune Alterations in a Postmenopausal-Stress Rat Model
Estrogen deficiency in postmenopausal women disrupts reproductive, metabolic, brain, and gut health, partly by promoting i...
Memantine/Rosuvastatin Therapy Abrogates Cognitive and Hippocampal Injury in an Experimental Model of Alzheimer's Disease in Rats: Role of TGF-β1/Smad Signaling Pathway and Amyloid-β Clearance
Memantine/Rosuvastatin Therapy Abrogates Cognitive and Hippocampal Injury in an Experimental Model of Alzheimer's Disease in Rats: Role of TGF-β1/Smad Signaling Pathway and Amyloid-β Clearance
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder of complex pathogenesis and multiple interac...
Empagliflozin Mitigates PTZ-Induced Seizures in Rats: Modulating Npas4 and CREB-BDNF Signaling Pathway
Empagliflozin Mitigates PTZ-Induced Seizures in Rats: Modulating Npas4 and CREB-BDNF Signaling Pathway
Empagliflozin (EMPA) is one of the sodium/glucose cotransporter 2 (SGLT2) inhibitors that has been recently approved for t...
Ghrelin Induces Ferroptosis Resistance and M2 Polarization of Microglia to Alleviate Neuroinflammation and Cognitive Impairment in Alzheimer’s Disease
Ghrelin Induces Ferroptosis Resistance and M2 Polarization of Microglia to Alleviate Neuroinflammation and Cognitive Impairment in Alzheimer’s Disease
Microglial polarization and ferroptosis are important pathological features in Alzheimer’s disease (AD). Ghrelin, a ...
LncRNA NEAT1, an Important Biomarker Involved in the Pathological and Physiological Processes of Parkinson's Disease
LncRNA NEAT1, an Important Biomarker Involved in the Pathological and Physiological Processes of Parkinson's Disease
Parkinson's disease (PD) is a complex progressive neurodegenerative disorder and the pathogenesis and treatment method...
The High-Affinity IL-2 Receptor Affects White Matter Damage after Cerebral Ischemia by Regulating CD8 + T Lymphocyte Differentiation
The High-Affinity IL-2 Receptor Affects White Matter Damage after Cerebral Ischemia by Regulating CD8 + T Lymphocyte Differentiation
IL-2/IL-2R inhibition improved the prognosis of ischemic stroke by regulating T cells, while the respective contribution o...
Modulation of Intestinal Inflammation and Protection of Dopaminergic Neurons in Parkinson’s Disease Mice through a Probiotic Formulation Targeting NLRP3 Inflammasome
Modulation of Intestinal Inflammation and Protection of Dopaminergic Neurons in Parkinson’s Disease Mice through a Probiotic Formulation Targeting NLRP3 Inflammasome
Emerging evidence highlights the significance of peripheral inflammation in the pathogenesis of Parkinson’s disease ...
A Comparative Study of Nanoconjugates of a Synthetic and a Natural Drug Against T2DM-Induced Cognitive Dysfunction
A Comparative Study of Nanoconjugates of a Synthetic and a Natural Drug Against T2DM-Induced Cognitive Dysfunction
Type II Diabetes Mellitus (T2DM) is one of the risk factors for the development of dementia leading to cognitive dysfuncti...
NXP032 Improves Memory Impairment Through Suppression of Tauopathy in PS19 Mice and Attenuates Okadaic Acid-Induced Tauopathy in SH-SY5Y Cells
NXP032 Improves Memory Impairment Through Suppression of Tauopathy in PS19 Mice and Attenuates Okadaic Acid-Induced Tauopathy in SH-SY5Y Cells
Tauopathy is widely observed in multiple neurodegenerative diseases such as Alzheimer’s disease (AD) and characteriz...
The Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation: A Systematic Review
The Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation: A Systematic Review
Stroke represents a significant burden on global health and the economy, with high mortality rates, disability, and recurr...
A New Perspective on Mechanisms of Neurodegeneration in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis: the Early and Critical Role of Platelets in Neuro/Axonal Loss
A New Perspective on Mechanisms of Neurodegeneration in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis: the Early and Critical Role of Platelets in Neuro/Axonal Loss
Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disorder, with limited treatment options. This diseas...
PKR Inhibition Prevents Neuroinflammation and Rescues Depressive-Like Behaviors via BDNF/TrkB Signaling
PKR Inhibition Prevents Neuroinflammation and Rescues Depressive-Like Behaviors via BDNF/TrkB Signaling
PKR, a kinase implicated in inflammation, accumulates in the brain, but its role in neuroinflammation-related depression i...
Rebalancing Immune Interactions within the Brain-Spleen Axis Mitigates Neuroinflammation in an Aging Mouse Model of Alzheimer’s Disease
Rebalancing Immune Interactions within the Brain-Spleen Axis Mitigates Neuroinflammation in an Aging Mouse Model of Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common cause of dementia worldwide, characterized by accumulation of amyloid-&#...
Proteomic Analysis of Chronic Binge Alcohol-Induced Hippocampal and Anterior Cingulate Cortex Neuroadaptations in Simian Immunodeficiency Virus (SIV)-Infected Female Rhesus Macaques
Proteomic Analysis of Chronic Binge Alcohol-Induced Hippocampal and Anterior Cingulate Cortex Neuroadaptations in Simian Immunodeficiency Virus (SIV)-Infected Female Rhesus Macaques
Human immunodeficiency virus (HIV) infection produces neurological comorbidities including HIV-associated neurocognitive d...
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