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Temporal changes in corticosteroid dose during ibrutinib treatment in patients with cGVHD and pulmonary involvement
Temporal changes in corticosteroid dose during ibrutinib treatment in patients with cGVHD and pulmonary involvement
The GVH3001 study assessed the efficacy and safety of ibrutinib in Japanese patients with steroid-dependent or -refractory...
Raising awareness may increase the likelihood of hematopoietic stem cell donation: a nationwide survey using artificial intelligence
Raising awareness may increase the likelihood of hematopoietic stem cell donation: a nationwide survey using artificial intelligence
In Italy, the demand for allogeneic transplantation exceeds the number of compatible donors in the Italian Bone Marrow Don...
Treatment trends and risks of corticosteroid use in adult primary immune thrombocytopenia: a claims database study in Japan
Treatment trends and risks of corticosteroid use in adult primary immune thrombocytopenia: a claims database study in Japan
Recent trends in the treatment of primary immune thrombocytopenia (ITP) were investigated using a claims database that inc...
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 2: hematologic malignancy
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 2: hematologic malignancy
Disseminated intravascular coagulation (DIC) associated with hematologic malignancies, particularly acute promyelocytic le...
Carcinocythemia diagnosed on peripheral blood clot sections
Carcinocythemia diagnosed on peripheral blood clot sections
Authors and AffiliationsDepartment of Haematological Medicine, King’s College Hospital NHS Foundation Trust, Denmark Hill,...
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 1: sepsis
Clinical practice guidelines for management of disseminated intravascular coagulation in Japan 2024. Part 1: sepsis
The Japanese Society on Thrombosis and Hemostasis (JSTH) published the first-ever disseminated intravascular coagulation (...
A practice-oriented genome-profiling study for acute myeloid leukemia using the novel HANDLE system: HM-screen-JAPAN02
A practice-oriented genome-profiling study for acute myeloid leukemia using the novel HANDLE system: HM-screen-JAPAN02
HM-SCREEN-Japan is a multicenter collaborative project in Japan to evaluate the clinical utility of a cancer genome panel ...
Outcomes of allogeneic SCT versus tisagenlecleucel in patients with R/R LBCL and poor prognostic factors
Outcomes of allogeneic SCT versus tisagenlecleucel in patients with R/R LBCL and poor prognostic factors
This study investigated the efficacy of tisagenlecleucel (tisa-cel) and allogeneic hematopoietic stem cell transplantation...
Chimerism analysis by ABO blood group genotyping with digital droplet PCR
Chimerism analysis by ABO blood group genotyping with digital droplet PCR
Chimerism analysis is an important post-transplant assessment for allogeneic hematopoietic stem cell transplant (HCT) reci...
DREAMM-11, Part 2: Japanese phase I trial of belantamab mafodotin combination therapies in relapsed/refractory multiple myeloma
DREAMM-11, Part 2: Japanese phase I trial of belantamab mafodotin combination therapies in relapsed/refractory multiple myeloma
DREAMM-11 (NCT03828292) was a Phase 1, open-label, dose-escalation study of belantamab mafodotin in Japanese patients with...
A 25-year clonal resurrection in adult T-cell leukemia-lymphoma relapse
A 25-year clonal resurrection in adult T-cell leukemia-lymphoma relapse
Here, we report a rare case of relapsed adult T-cell leukemia-lymphoma (ATL) with evidence of clonal relapse 26 y...
Cost-effectiveness of ferric citrate hydrate in patients with iron deficiency anemia
Cost-effectiveness of ferric citrate hydrate in patients with iron deficiency anemia
We investigated the cost-effectiveness of treating iron deficiency anemia (IDA) with ferric citrate hydrate (FC) in Japan....
Isatuximab plus pomalidomide and dexamethasone in frail individuals with relapsed/refractory multiple myeloma in Japan
Isatuximab plus pomalidomide and dexamethasone in frail individuals with relapsed/refractory multiple myeloma in Japan
This post-marketing surveillance (PMS) assessed the safety and effectiveness of isatuximab plus pomalidomide and dexametha...
Pseudo-Chediak–Higashi inclusions and Auer rods in a case of therapy-related acute monocytic leukemia
Pseudo-Chediak–Higashi inclusions and Auer rods in a case of therapy-related acute monocytic leukemia
Conflict of interest The author has no conflict of interest. ...
Nodal mature plasmacytoid dendritic cell proliferation mimicking lymphoma in a patient with CALR-mutated myelofibrosis
Nodal mature plasmacytoid dendritic cell proliferation mimicking lymphoma in a patient with CALR-mutated myelofibrosis
Cite this articleMagnoli, F., Brociner, M. & La Rosa, S. Nodal mature plasmacytoid dendritic cell proliferation mimick...
Silent inactivation of asparaginase in Japan: results of the prospective ALL-ASP19 trial
Silent inactivation of asparaginase in Japan: results of the prospective ALL-ASP19 trial
Silent inactivation (SI) of L-asparaginase (ASP) is a phenomenon by which a neutralizing antibody for ASP (AAA) decreases ...
A lower initial dose of bosutinib for patients with chronic myeloid leukemia patients resistant and/or intolerant to prior therapy: a single-arm, multicenter, phase 2 trial (BOGI trial)
A lower initial dose of bosutinib for patients with chronic myeloid leukemia patients resistant and/or intolerant to prior therapy: a single-arm, multicenter, phase 2 trial (BOGI trial)
Although bosutinib is generally safe and effective, drug-related toxicities (DRTs) such as diarrhea or increased transamin...
Efficacy and safety of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A
Efficacy and safety of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A
Acquired hemophilia A (AHA) is a rare bleeding disorder caused by autoantibodies inhibiting human factor VIII (hFVIII). Th...
JSH practical guidelines for hematological malignancies, 2023: leukemia-3. Acute lymphoblastic leukemia/lymphoblastic lymphoma: ALL/LBL
JSH practical guidelines for hematological malignancies, 2023: leukemia-3. Acute lymphoblastic leukemia/lymphoblastic lymphoma: ALL/LBL
Conflict of interest KI has received per diem, including sp...
Clinical impact of airflow obstruction after allogeneic hematopoietic stem cell transplantation
Clinical impact of airflow obstruction after allogeneic hematopoietic stem cell transplantation
Criteria for airflow obstruction (AFO) at one year after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in...
Immunohistochemical differentiation of extramedullary acute myeloid leukemia from blastic plasmacytoid dendritic cell neoplasm
Immunohistochemical differentiation of extramedullary acute myeloid leukemia from blastic plasmacytoid dendritic cell neoplasm
We extend our deepest appreciation to the entire medical team at Yokohama Municipal Citizen's Hospital for their unwaverin...
Trametinib for a child with refractory Rosai–Dorfman–Destombes disease harboring a novel somatic mutation in MAP2K1
Trametinib for a child with refractory Rosai–Dorfman–Destombes disease harboring a novel somatic mutation in MAP2K1
Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytosis characterized by accumulation of S100 +...
CAR-T cell therapy in AML: recent progress and future perspectives
CAR-T cell therapy in AML: recent progress and future perspectives
Despite several small-molecule drugs that have revolutionized the current treatment strategy for acute myeloid leukemia (A...
Precision medicine in AML: overcoming resistance
Precision medicine in AML: overcoming resistance
The development of molecularly targeted therapy for acute myeloid leukemia is progressing at an accelerated pace. Therapie...
Bilateral development of biclonal ocular adnexal marginal zone lymphoma at a 2-year interval
Bilateral development of biclonal ocular adnexal marginal zone lymphoma at a 2-year interval
Ocular adnexal marginal zone B-cell lymphoma (OAMZL) of the mucosa-associated lymphoid tissue is a distinct subtype of B-c...
Pathological landscape of tumor flare reaction to epcoritamab treatment
Pathological landscape of tumor flare reaction to epcoritamab treatment
Tumor flare reaction (TFR) is characterized by an increase in lesion size during immune-based therapy, often resembling di...
Metabolic dependencies of acute myeloid leukemia stem cells
Metabolic dependencies of acute myeloid leukemia stem cells
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy primarily driven by an immature population of AML c...
Molecular pathophysiology of germline mutations in acute myeloid leukemia
Molecular pathophysiology of germline mutations in acute myeloid leukemia
Germline (GL) predisposition to acute myeloid leukemia (AML) has been established as an independent disease entity in the ...
Ruxolitinib for steroid-refractory chronic graft-versus-host disease: Japanese subgroup analysis of REACH3 study
Ruxolitinib for steroid-refractory chronic graft-versus-host disease: Japanese subgroup analysis of REACH3 study
Ruxolitinib, a Janus kinase (JAK1–JAK2) inhibitor, has demonstrated safety and efficacy in patients with graft-versu...
Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera
Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera
Ropeginterferon alfa-2b (ropegIFN), a new-generation interferon-based agent, has been approved in Japan for patients with ...
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