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Organ Fibrosis: Emerging diagnostic and therapeutic strategies
Organ Fibrosis: Emerging diagnostic and therapeutic strategies
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis
Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis
Systemic sclerosis (also called scleroderma, SSc) is a chronic autoimmune disorder characterized by excessive collagen dep...
Recent advances in intestinal fibrosis
Recent advances in intestinal fibrosis
Intestinal fibrosis is characterised by the accumulation of extracellular matrix (ECM) within the intestinal walls (Lenti ...
Are we getting closer to a successful neoantigen cancer vaccine?
Are we getting closer to a successful neoantigen cancer vaccine?
Over the past decade, significant advances in immunotherapy, such as already approved by regulatory agencies several immun...
Improving the quality of quantitative polymerase chain reaction experiments: 15 years of MIQE
Improving the quality of quantitative polymerase chain reaction experiments: 15 years of MIQE
Volume 96, April 2024, 101249Author links open overlay panelAbstractThe quantitative polymerase chain reaction (qPCR) is f...
Current and emerging sequencing-based tools for precision cancer medicine
Current and emerging sequencing-based tools for precision cancer medicine
Cancer is caused by a vast number of recurrent genetic alterations important for disease initiation, progression and relap...
Digital PCR for the characterization of reference materials
Digital PCR for the characterization of reference materials
Volume 96, April 2024, 101256Author links open overlay panel, , , , , AbstractWell-characterized reference materials suppo...
Principles of digital sequencing using unique molecular identifiers
Principles of digital sequencing using unique molecular identifiers
Massively parallel sequencing technologies have long been used in both basic research and clinical routine. The recent int...
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing
Single-cell and spatial transcriptomics: Bridging current technologies with long-read sequencing
Single-cell technologies have transformed biomedical research over the last decade, opening up new possibilities for under...
Circulating tumor cells as liquid biopsy markers in cancer patients
Circulating tumor cells as liquid biopsy markers in cancer patients
Volume 96, April 2024, 101258Author links open overlay panel, Highlights•CTCs are tumor cells circulating in the blood.•CT...
E3 ubiquitin ligase WWP2 as a promising therapeutic target for diverse human diseases
E3 ubiquitin ligase WWP2 as a promising therapeutic target for diverse human diseases
Protein ubiquitination is a dynamic multifaceted post-translational modification in which ubiquitin (Ub), a small 76 amino...
Cancer-associated muscle weakness - From triggers to molecular mechanisms
Cancer-associated muscle weakness - From triggers to molecular mechanisms
Skeletal muscle weakness is a debilitating consequence of many malignancies. Muscle weakness has a negative impact on both...
Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies
Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies
The onset of sarcopenia is intimately linked with aging, posing significant implications not only for individual patient q...
DNA melting analysis
DNA melting analysis
Separation of the two strands of DNA is necessary for semiconservative replication and cell division (Meselson and Stahl, ...
A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics
A pipeline for the development and analysis of extracellular vesicle-based transcriptomic biomarkers in molecular diagnostics
Extracellular vesicles are shed by every cell type and can be found in any biofluid. They contain different molecules that...
Liver fibrosis in NAFLD/NASH: from pathophysiology towards diagnostic and therapeutic strategies
Liver fibrosis in NAFLD/NASH: from pathophysiology towards diagnostic and therapeutic strategies
Volume 95, February 2024, 101231Author links open overlay panel, Highlights•Concepts and mechanisms responsible for liver ...
Invited review liver fibrosis in NAFLD/NASH: From pathophysiology towards diagnostic and therapeutic strategies
Invited review liver fibrosis in NAFLD/NASH: From pathophysiology towards diagnostic and therapeutic strategies
Volume 95, February 2024, 101231Author links open overlay panel, Highlights•Concepts and mechanisms responsible for liver ...