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Lactobacillaceae-mediated eye-brain-gut axis regulates high myopia-related anxiety: from the perspective of predictive, preventive, and personalized medicine
Lactobacillaceae-mediated eye-brain-gut axis regulates high myopia-related anxiety: from the perspective of predictive, preventive, and personalized medicine
High myopia has become a major cause of blindness worldwide and can contribute to emotional deficits through its impact on...
Pharmacoproteomics reveals energy metabolism pathways as therapeutic targets of ivermectin in ovarian cancer toward 3P medical approaches
Pharmacoproteomics reveals energy metabolism pathways as therapeutic targets of ivermectin in ovarian cancer toward 3P medical approaches
Ovarian cancer is the malignant tumor with the highest mortality rate in the female reproductive system, enormous socio-ec...
Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Pain chronification risk assessment: advanced phenotyping and scoring for prediction and treatments tailored to individualized patient profile
Acute pain is a physiologic, protective life-important warning neurological signal indicating multi-level tissue modulatio...
Changes in the metabolic score for insulin resistance index for risk prediction of stroke in middle-aged and older Chinese population
Changes in the metabolic score for insulin resistance index for risk prediction of stroke in middle-aged and older Chinese population
As a major noncommunicable disease, stroke poses a major threat to public health. In the context of predictive, preventati...
Mitochondria-based holistic 3PM approach as the ‘game-changer’ for individualised rehabilitation—the proof-of-principle model by treated breast cancer survivors
Mitochondria-based holistic 3PM approach as the ‘game-changer’ for individualised rehabilitation—the proof-of-principle model by treated breast cancer survivors
Breast cancer belongs to the most commonly diagnosed malignancies worldwide, with its increasing incidence paralleled by a...
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies
Lung adenocarcinoma (LUAD) remains a significant global health challenge, with an urgent need for innovative predictive, p...
Pyridoxal 5′-phosphate and risk of stroke: triangulation of evidence from a nationally representative cohort and bidirectional Mendelian randomization analysis
Pyridoxal 5′-phosphate and risk of stroke: triangulation of evidence from a nationally representative cohort and bidirectional Mendelian randomization analysis
Stroke is a leading cause of mortality and disability worldwide. Identifying predictive biomarkers and modifiable risk fac...
Eye yoga for glaucoma: recovery of vascular dysregulation and visual field function—a randomized controlled trial
Eye yoga for glaucoma: recovery of vascular dysregulation and visual field function—a randomized controlled trial
Because stress can aggravate vascular dysregulation (VD) in primary open-angle glaucoma (POAG), stress reduction by eye yo...
Epigenetic and biogenetic regulation by polyphenols in prostate cancer in the context of 3P medicine
Epigenetic and biogenetic regulation by polyphenols in prostate cancer in the context of 3P medicine
Prostate cancer (PCa) can remain asymptomatic for years, complicating early detection and effective intervention. Predicti...
Big data for neuroscience in the context of predictive, preventive, and personalized medicine
Big data for neuroscience in the context of predictive, preventive, and personalized medicine
Accurate and precise diagnosis made the medicine the hallmark of evidence-based medicine. While attaining absolute patient...
Identifying Specificity Protein 2 as a key marker for diabetic encephalopathy in the context of predictive, preventive, and personalized medicine
Identifying Specificity Protein 2 as a key marker for diabetic encephalopathy in the context of predictive, preventive, and personalized medicine
Transcription factor specificity protein (SP2) regulates various cellular functions, including cell division, proliferatio...
Multiomics as instrument to promote 3P medical approaches for the overall management of respiratory syncytial viral infections
Multiomics as instrument to promote 3P medical approaches for the overall management of respiratory syncytial viral infections
Respiratory syncytial viral (RSV) infection is a leading persisting pulmonary disease-causing agent. It causes loss of liv...
Physical activity, cardiovascular disease, and mortality across obesity levels
Physical activity, cardiovascular disease, and mortality across obesity levels
High physical activity (PA) is associated with decreased risk of cardiovascular disease (CVD) and mortality. However, whet...
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
Prediction of risk for isolated incomplete lateral meniscal injury using a dynamic nomogram based on MRI-derived anatomic radiomics and physical activity: a proof-of-concept study in 3PM-guided management
The 3PM framework revolutionizes disease management by facilitating early risk prediction, disease prevention, and persona...
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Association of prebiotic/probiotic intake with MASLD: evidence from NHANES and randomized controlled trials in the context of prediction, prevention, and a personalized medicine framework
Metabolic-associated fatty liver disease (MASLD) is a growing global health concern. From the standpoint of preventive and...
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
Metabolomics measurements of eccrine sweat may provide novel and relevant biomedical information to support predictive, pr...
Immune-related gene methylation prognostic instrument for stratification and targeted treatment of ovarian cancer patients toward advanced 3PM approach
Immune-related gene methylation prognostic instrument for stratification and targeted treatment of ovarian cancer patients toward advanced 3PM approach
DNA methylation is an important mechanism in epigenetics, which can change the transcription ability of genes and is close...
The Emergency Medical Team Operating System — a vision for field hospital data management in following the concepts of predictive, preventive, and personalized medicine
The Emergency Medical Team Operating System — a vision for field hospital data management in following the concepts of predictive, preventive, and personalized medicine
In times where sudden-onset disasters (SODs) present challenges to global health systems, the integration of predictive, p...
Energy metabolism as the hub of advanced non-small cell lung cancer management: a comprehensive view in the framework of predictive, preventive, and personalized medicine
Energy metabolism as the hub of advanced non-small cell lung cancer management: a comprehensive view in the framework of predictive, preventive, and personalized medicine
Energy metabolism is a hub of governing all processes at cellular and organismal levels such as, on one hand, reparable vs...
Digital biomarkers: 3PM approach revolutionizing chronic disease management — EPMA 2024 position
Digital biomarkers: 3PM approach revolutionizing chronic disease management — EPMA 2024 position
Non-communicable chronic diseases (NCDs) have become a major global health concern. They constitute the leading cause of d...
Application of ChatGPT-4 to oculomics: a cost-effective osteoporosis risk assessment to enhance management as a proof-of-principles model in 3PM
Application of ChatGPT-4 to oculomics: a cost-effective osteoporosis risk assessment to enhance management as a proof-of-principles model in 3PM
Oculomics is an emerging medical field that focuses on the study of the eye to detect and understand systemic diseases. Ch...
Liver function maximum capacity test during normothermic regional perfusion predicts graft function after transplantation
Liver function maximum capacity test during normothermic regional perfusion predicts graft function after transplantation
In an effort to reduce waitlist mortality, extended criteria donor organs, including those from donation after circulatory...
Artificial intelligence in ovarian cancer drug resistance advanced 3PM approach: subtype classification and prognostic modeling
Artificial intelligence in ovarian cancer drug resistance advanced 3PM approach: subtype classification and prognostic modeling
Ovarian cancer patients’ resistance to first-line treatment posed a significant challenge, with approximately 70% ex...
Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Clinical data are essential for developing cloud platforms for intelligent diagnosis and treatment decision of diseases. H...
Association of the weight-adjusted waist index with hypertension in the context of predictive, preventive, and personalized medicine
Association of the weight-adjusted waist index with hypertension in the context of predictive, preventive, and personalized medicine
Hypertension (HTN) is a prevalent global health concern. From the standpoint of preventive and personalized medicine (PPPM...
The caregiving role influences Suboptimal Health Status and psychological symptoms in unpaid carers
The caregiving role influences Suboptimal Health Status and psychological symptoms in unpaid carers
Suboptimal Health Status (SHS) is the physical state between health and disease. This study aimed to fill in the knowledge...
Genetic association of lipid traits and lipid-related drug targets with normal tension glaucoma: a Mendelian randomization study for predictive preventive and personalized medicine
Genetic association of lipid traits and lipid-related drug targets with normal tension glaucoma: a Mendelian randomization study for predictive preventive and personalized medicine
Glaucoma is the leading cause of irreversible blindness worldwide. Normal tension glaucoma (NTG) is a distinct subtype cha...
Body fluid multiomics in 3PM-guided ischemic stroke management: health risk assessment, targeted protection against health-to-disease transition, and cost-effective personalized approach are envisaged
Body fluid multiomics in 3PM-guided ischemic stroke management: health risk assessment, targeted protection against health-to-disease transition, and cost-effective personalized approach are envisaged
Because of its rapid progression and frequently poor prognosis, stroke is the third major cause of death in Europe and the...
Resveratrol: potential application in safeguarding testicular health
Resveratrol: potential application in safeguarding testicular health
Factors such as increasing mental pressure and poor living habits in modern society have led to an increase in the inciden...
The predictive, preventive, and personalized medicine of depression: gut microbiota and inflammation
The predictive, preventive, and personalized medicine of depression: gut microbiota and inflammation
Gut microbiota (GM) is closely associated with the onset of depression, in which inflammation plays an essential role. Ide...
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