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Risk characteristics of papillary thyroid cancer > 1–4 cm is associated with increased tumour size
Risk characteristics of papillary thyroid cancer > 1–4 cm is associated with increased tumour size
Recent guidelines recommend total thyroidectomy for papillary thyroid cancers (PTC) larger than 4 cm. For papillary macroc...
Efficacy and safety of a new 10% intravenous immunoglobulin (IVIG) in Chinese patients with primary immune thrombocytopenia (ITP): a multicenter, single-arm, phase III trial
Efficacy and safety of a new 10% intravenous immunoglobulin (IVIG) in Chinese patients with primary immune thrombocytopenia (ITP): a multicenter, single-arm, phase III trial
A novel, highly purified 10% intravenous immunoglobulin (IVIG) formulation was evaluated for both therapeutic efficacy and...
A machine learning-based prediction model for colorectal liver metastasis
A machine learning-based prediction model for colorectal liver metastasis
Colorectal liver metastasis (CRLM) is a primary factor contributing to poor prognosis and metastasis in colorectal cancer ...
Reduced-dose donor lymphocyte infusion is a viable therapeutic strategy for Epstein–Barr virus-related post-transplant lymphoproliferative disease after hematopoietic stem cell transplantation: a single-center experience
Reduced-dose donor lymphocyte infusion is a viable therapeutic strategy for Epstein–Barr virus-related post-transplant lymphoproliferative disease after hematopoietic stem cell transplantation: a single-center experience
Post-transplant lymphoproliferative disease (PTLD) is a life-threatening complication of hematopoietic stem cell transplan...
Revealing roles of PANoptosis-related genes in prognosis and molecular subtypes in lung squamous cell carcinoma by integrated bioinformatic analyses and experiments
Revealing roles of PANoptosis-related genes in prognosis and molecular subtypes in lung squamous cell carcinoma by integrated bioinformatic analyses and experiments
The purpose of current study was to reveal the role of PANoptosis-associated genes in lung squamous cell carcinoma (LUSC) ...
The persistent risk of secondary malignancies in gastric neuroendocrine tumor survivors: a population-based analysis
The persistent risk of secondary malignancies in gastric neuroendocrine tumor survivors: a population-based analysis
Gastric neuroendocrine tumors (G-NETs) are rare neoplasms with a favorable survival rate, yet they present a significant r...
Dynamic role of long noncoding RNA in liver diseases: pathogenesis and diagnostic aspects
Dynamic role of long noncoding RNA in liver diseases: pathogenesis and diagnostic aspects
Liver disease (LD) is complex pathological condition that has emerged as a major threat to human health and the quality of...
A novel composite model for distinguishing benign and malignant pulmonary nodules
A novel composite model for distinguishing benign and malignant pulmonary nodules
Previous studies have demonstrated that a four-protein marker panel (4MP), consisting of Pro-SFTPB, CA125, Cyfra21-1, and ...
Bidirectional association between uveitis and psoriasis: a systematic review and meta-analysis
Bidirectional association between uveitis and psoriasis: a systematic review and meta-analysis
In recent years, the prevalence of uveitis among patients with psoriasis has shown a noticeable upward trend. Previous stu...
Platelet-rich plasma-derived exosomes accelerate the healing of diabetic foot ulcers by promoting macrophage polarization toward the M2 phenotype
Platelet-rich plasma-derived exosomes accelerate the healing of diabetic foot ulcers by promoting macrophage polarization toward the M2 phenotype
Diabetic foot ulcers (DFUs) impose a significant clinical and socioeconomic burden on patients and healthcare systems. Alt...
Identification and functional characterization of hub genes CLTA, EDIL3, HAPLN1, and HIP1 as diagnostic biomarkers and therapeutic targets in thyroid cancer and Hashimoto’s thyroiditis
Identification and functional characterization of hub genes CLTA, EDIL3, HAPLN1, and HIP1 as diagnostic biomarkers and therapeutic targets in thyroid cancer and Hashimoto’s thyroiditis
In this study, we sought to identify key molecular players in both thyroid cancer (TC) and Hashimoto's thyroiditis (HT...
Myosteatosis and the survival of patients with hepatocellular carcinoma: a meta-analysis
Myosteatosis and the survival of patients with hepatocellular carcinoma: a meta-analysis
Myosteatosis, characterized by fat infiltration into skeletal muscle, is increasingly recognized as a prognostic factor in...
Complex association of mean corpuscular volume and outcomes in patients with aplastic anemia treated with cyclosporine A plus androgen or cyclosporine A alone
Complex association of mean corpuscular volume and outcomes in patients with aplastic anemia treated with cyclosporine A plus androgen or cyclosporine A alone
The aim of this study was to explore the prognostic value of mean corpuscular volume (MCV) in newly diagnosed aplastic ane...
Machine learning and single-cell analysis uncover distinctive characteristics of CD300LG within the TNBC immune microenvironment: experimental validation
Machine learning and single-cell analysis uncover distinctive characteristics of CD300LG within the TNBC immune microenvironment: experimental validation
Investigating the essential function of CD300LG within the tumor microenvironment in triple-negative breast cancer (TNBC)....
Nanotechnology in leukemia therapy: revolutionizing targeted drug delivery and immune modulation
Nanotechnology in leukemia therapy: revolutionizing targeted drug delivery and immune modulation
Leukemia, a group of blood cancers, presents a significant global health challenge. Despite advancements in conventional t...
AHNAK2 confers 5-fluorouracil resistance in colorectal cancer via activation of the AKT/GSK-3β signaling axis
AHNAK2 confers 5-fluorouracil resistance in colorectal cancer via activation of the AKT/GSK-3β signaling axis
AHNAK nucleoprotein 2 (AHNAK2) is implicated in tumor progression and survival signaling, yet its role in chemotherapy res...
Identification and validation a novel kinase-related gene signature for predicting prognosis and responsiveness to immunotherapy in hepatocellular carcinoma
Identification and validation a novel kinase-related gene signature for predicting prognosis and responsiveness to immunotherapy in hepatocellular carcinoma
Liver cancer research highlights the kinome's critical role in disease initiation and progression. However, comprehens...
Multidimensional integrated lung protection measures attenuate pulmonary inflammation and improve lung function by inhibiting the NF-κB signaling pathway in elderly patients with lung dysfunction
Multidimensional integrated lung protection measures attenuate pulmonary inflammation and improve lung function by inhibiting the NF-κB signaling pathway in elderly patients with lung dysfunction
Elderly patients with lung dysfunction (EPLD) often experience chronic inflammation and impaired immune responses, signifi...
The role of trimethoprim/sulfamethoxazole in preventing opportunistic infections in systemic lupus erythematosus patients receiving low-level immunosuppressive treatment: an open-label, randomized, controlled trial
The role of trimethoprim/sulfamethoxazole in preventing opportunistic infections in systemic lupus erythematosus patients receiving low-level immunosuppressive treatment: an open-label, randomized, controlled trial
Objective: Systemic lupus erythematosus (SLE) patients receiving immunosuppressive therapy are at risk for opportunistic i...
SASS6 promotes tumor proliferation and is associated with TP53 and immune infiltration in lung adenocarcinoma
SASS6 promotes tumor proliferation and is associated with TP53 and immune infiltration in lung adenocarcinoma
The most common type of non-small cell lung cancer is lung adenocarcinoma (LUAD), which is characterized by high morbidity...
CXCL13: a common target for immune-mediated inflammatory diseases
CXCL13: a common target for immune-mediated inflammatory diseases
CXCL13 is a chemokine that plays an important role in the regulation and development of secondary lymphoid organs. CXCL13 ...
Influence of recipient KRAS gene rs712 polymorphisms on the overall survival rate of hepatocellular carcinoma after hepatic transplantation
Influence of recipient KRAS gene rs712 polymorphisms on the overall survival rate of hepatocellular carcinoma after hepatic transplantation
Hepatocellular carcinoma (HCC) recurrence appears commonly after liver transplantation (LT), and it severely affected the ...
Risk of subsequent primary cancers in bladder cancer survivors
Risk of subsequent primary cancers in bladder cancer survivors
We aimed to investigate the risk of bladder cancer (BCa) survivors developing or dying from 15 specific-subsequent primary...
Genetics, diet, microbiota, and metabolome: partners in crime for colon carcinogenesis
Genetics, diet, microbiota, and metabolome: partners in crime for colon carcinogenesis
Colorectal cancer (CRC) ranks among the most prevalent malignant tumors worldwide, with a multifactorial etiology encompas...
Identifying the prognostic significance of mitophagy-associated genes in multiple myeloma: a novel risk model construction
Identifying the prognostic significance of mitophagy-associated genes in multiple myeloma: a novel risk model construction
Multiple myeloma (MM) is a highly heterogeneous hematological malignancy that is currently incurable. Individualized thera...
GUCA2A dysregulation as a promising biomarker for accurate diagnosis and prognosis of colorectal cancer
GUCA2A dysregulation as a promising biomarker for accurate diagnosis and prognosis of colorectal cancer
Colorectal cancer is a leading cause of global mortality and presents a significant barrier to improving life expectancy. ...
Early minimal residual disease eradication in light chain amyloidosis generates deeper and faster cardiac response
Early minimal residual disease eradication in light chain amyloidosis generates deeper and faster cardiac response
Minimal residual disease (MRD) is of growing interest in light chain (AL) amyloidosis and is associated with higher rates ...
Development and validation of a model for predicting who can benefit from multiple TACE in HCC patients
Development and validation of a model for predicting who can benefit from multiple TACE in HCC patients
This study was to develop and validate a model for predicting who can benefit from multiple transcatheter arterial chemoem...
Tumor-immune hybrid cells evade the immune response and potentiate colorectal cancer metastasis through CTLA4
Tumor-immune hybrid cells evade the immune response and potentiate colorectal cancer metastasis through CTLA4
Understanding the metastatic cascade is critical for the treatment and prevention of cancer-related death. Within a tumor,...
Analysis of METTL14 expression in pancreatic cancer and adjacent tissues and its prognostic value for patient outcomes
Analysis of METTL14 expression in pancreatic cancer and adjacent tissues and its prognostic value for patient outcomes
This study aims to analyze the differential expression of METTL14 in pancreatic cancer (PC) tissues and adjacent normal ti...
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