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Meclozine and growth hormone ameliorate bone length and quality in experimental models of achondroplasia
Meclozine and growth hormone ameliorate bone length and quality in experimental models of achondroplasia
Achondroplasia (ACH) is a common skeletal dysplasia associated with short-limbed short stature caused by gain-of-function ...
Nutrient foramina of human fibula: morphometric analysis and clinical relevance
Nutrient foramina of human fibula: morphometric analysis and clinical relevance
The fibula, situated laterally in the leg, receives vital nutrition through nutrient arteries during embryonic bone growth...
Histological assessments for anabolic effects in teriparatide/abaloparatide administered rodent models
Histological assessments for anabolic effects in teriparatide/abaloparatide administered rodent models
Parathyroid hormone (PTH) is thought to induce remodeling-based bone formation by promoting osteoclastic activity, a proce...
Multiple thyroid disorders and risk of osteoporosis: a two-sample Mendelian randomization study
Multiple thyroid disorders and risk of osteoporosis: a two-sample Mendelian randomization study
Previous research has demonstrated that even minor changes in thyroid function are associated with an increased risk of os...
Osteoporosis screening using X-ray assessment and osteoporosis self-assessment tool for Asians in hip surgery patients
Osteoporosis screening using X-ray assessment and osteoporosis self-assessment tool for Asians in hip surgery patients
As many patients with osteoporosis remain undiagnosed, we aimed to develop a simple method to efficiently screen for osteo...
Thoracolumbar kyphosis prognoses poor results after proximal femoral fracture: a 3-year multicenter prospective cohort study
Thoracolumbar kyphosis prognoses poor results after proximal femoral fracture: a 3-year multicenter prospective cohort study
Proximal femoral fractures are critically associated with increased risk of mortality and secondary fractures. Identifying...
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis
Osteoarthritis (OA) is a chronic degenerative joint disorder characterized by an imbalance in chondrocyte metabolism. Ferr...
Osteoporosis and stroke: a bidirectional mendelian randomization study
Osteoporosis and stroke: a bidirectional mendelian randomization study
Numerous observational studies have identified a link between osteoporosis and stroke. However, the causal genetic relatio...
Correlation between serum high-density lipoprotein cholesterol and bone mineral density in vitamin D-deficient populations
Correlation between serum high-density lipoprotein cholesterol and bone mineral density in vitamin D-deficient populations
To investigate the relationship between serum high-density lipoprotein (HDL) cholesterol and bone mineral density (BMD) in...
Associations between bone material strength index and FRAX scores
Associations between bone material strength index and FRAX scores
Impact microindentation (IMI) measures bone material strength index (BMSi) in vivo. However, its ability to predict fractu...
Insights into skeletal involvement in adult Gaucher disease: a single-center experience
Insights into skeletal involvement in adult Gaucher disease: a single-center experience
Gaucher disease (GD) is a lysosomal storage disorder causing systemic and skeletal complications. This study evaluates bon...
Impact of mechanotransduction on gene expression changes in periodontal ligament during orthodontic tooth movement
Impact of mechanotransduction on gene expression changes in periodontal ligament during orthodontic tooth movement
The periodontal ligament (PDL) is a structure between the alveolar bone and cementum, essential for tooth stability and co...
Correction: Risk factors for incident vertebral fractures in osteoporosis pharmacotherapy: a 2-year, prospective, observational study
Correction: Risk factors for incident vertebral fractures in osteoporosis pharmacotherapy: a 2-year, prospective, observational study
Adjusted hazard ratio for incident vertebral fracture according to baseline values. ucOC undercarboxylated osteocalcin, BA...
Correction: Effect of CBX7 deficiency on the socket healing after tooth extractions
Correction: Effect of CBX7 deficiency on the socket healing after tooth extractions
Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, No. 140, Hanzhong Road, Nanjing, 210029, People’s Rep...
Chemotherapy effects on bone mineral density and microstructure in women with breast cancer
Chemotherapy effects on bone mineral density and microstructure in women with breast cancer
Chemotherapy involves the administration of steroids to prevent nausea and vomiting; however, its effect on bone microstru...
A crossover comparison of patient satisfaction with two teriparatide regimens: primary results of the Japanese Osteoporosis Intervention Trial 06 (JOINT-06)
A crossover comparison of patient satisfaction with two teriparatide regimens: primary results of the Japanese Osteoporosis Intervention Trial 06 (JOINT-06)
This study aimed to compare treatment satisfaction with two dosing regimens (two teriparatide [TPTD] self-injection system...
Olink and gut microbial metabolomics reveal new biomarkers for the prediction and diagnosis of PMOP
Olink and gut microbial metabolomics reveal new biomarkers for the prediction and diagnosis of PMOP
Postmenopausal osteoporosis (PMOP) can cause postmenopausal women to experience pain and interference. Identifying and exp...
Perturbations in gut microbiota composition in osteoporosis: a systematic review and meta-analysis
Perturbations in gut microbiota composition in osteoporosis: a systematic review and meta-analysis
Osteoporosis (OP) is a chronic bone metabolic disease, which causes a great social and economic burden. The gut microbiota...
Efficacy and safety of romosozumab: a meta-analysis of placebo-controlled trials
Efficacy and safety of romosozumab: a meta-analysis of placebo-controlled trials
We aimed to comprehensively compile placebo-controlled trials on the efficacy and safety of romosozumab (210 mg, ...
Deletion of Bmal1 in aggrecan-expressing cells leads to mouse temporomandibular joint osteoarthritis
Deletion of Bmal1 in aggrecan-expressing cells leads to mouse temporomandibular joint osteoarthritis
Articular cartilage is the major affected tissue during the development of osteoarthritis (OA) in temporomandibular joint ...
Temporal declines in bone mineral density and trabecular bone score during androgen deprivation therapy
Temporal declines in bone mineral density and trabecular bone score during androgen deprivation therapy
The trabecular bone score (TBS) has emerged as a convenient measure for assessing the microstructure of trabecular bone in...
Updated reference values for BMD and lean mass measured by DXA in Thai children
Updated reference values for BMD and lean mass measured by DXA in Thai children
This study established normative references for total body less head (TBLH) BMD, lumbar spine (L1–L4) BMD, and both ...
Wnt family members regulating osteogenesis and their origins
Wnt family members regulating osteogenesis and their origins
Wnt signaling plays an important role in the regulation of bone metabolism. Wnt activates the β-catenin-mediated cano...
Real-life effects of pharmacological osteoporosis treatments on bone mineral density by quantitative computed tomography
Real-life effects of pharmacological osteoporosis treatments on bone mineral density by quantitative computed tomography
Monitoring of bone mineral density (BMD) is used to assess pharmacological osteoporosis therapy. This study examined the r...
Gender differences between smoking and the risk of hip fracture
Gender differences between smoking and the risk of hip fracture
This study aimed to estimate the relation between cigarette smoking and hip fracture in men compared with women using a me...
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Efficacy of a single 5 mg zoledronic acid infusion in preventing bone loss and fracture in postmenopausal women with breast cancer
Chemotherapy-induced bone loss (CTIBL) is common among breast cancer patients, requiring comprehensive assessment and inte...
Accelerated bone loss in late reproductive-aged and perimenopausal women with vitamin D insufficiency
Accelerated bone loss in late reproductive-aged and perimenopausal women with vitamin D insufficiency
The association between serum vitamin D levels and bone mineral density (BMD) varies by race and gender. This study aimed ...
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7
Hedgehog and canonical Wnt signaling pathways and the transcription factors Runx2 and Sp7 are essential for osteoblast dif...
Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis
Disulfiram ameliorates bone loss in ovariectomized mice by suppressing osteoclastogenesis
Disulfiram (DSF), known as an anti-alcoholism drug, has been reported to suppress osteoclast differentiation in vitro; how...
The efficacy of nutritional screening indexes in predicting the incidence of osteosarcopenia and major osteoporotic fracture in the elderly
The efficacy of nutritional screening indexes in predicting the incidence of osteosarcopenia and major osteoporotic fracture in the elderly
The effect of nutritional status on osteosarcopenia (OS) and major osteoporotic fracture (MOF) among the elderly is still ...
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