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Getting anxious about immune system activation
A possible mechanism for the increased incidence of mood disorders in people with immune system disorders such as psoriasi...
Exploring the complexity of MECP2 function in Rett syndrome
Exploring the complexity of MECP2 function in Rett syndrome
Rett syndrome (RTT) is a neurodevelopmental disorder that is mainly caused by mutations in the methyl-DNA-binding protein ...
Indigenous representation in neuroscience scholarship, teaching and care
Despite a global push to recognize Indigenous knowledge systems in research, neuroscience remains embedded in Euro-Western...
Brain mechanisms underlying the inhibitory control of thought
Brain mechanisms underlying the inhibitory control of thought
Controlling action and thought requires the capacity to stop mental processes. Over the past two decades, evidence has gro...
Neuroferroptosis in health and diseases
Neuroferroptosis in health and diseases
Ferroptosis is a type of cell death process defined by iron-dependent peroxidation of phospholipids leading to the destruc...
Sleuthing subjectivity: a review of covert measures of consciousness
Sleuthing subjectivity: a review of covert measures of consciousness
Consciousness is private. Although conscious beings directly access their own conscious experiences, the consciousness of ...
On analogies in vertebrate and insect visual systems
On analogies in vertebrate and insect visual systems
Despite the large evolutionary distance between vertebrates and insects, the visual systems of these two taxa bear remarka...
Inflammation alters cognition after cancer immunotherapy
Neuroinflammatory mechanisms drive cognitive impairments in mice treated with chimeric antigen receptor (CAR)-T cell therapy.
Opening the gate to regeneration
After injury, regeneration of retinal ganglion cells and reconnection to their original target — the suprachiasmatic...
Fly connectome over the wire
A series of papers provide an overview of the adult Drosophila melanogaster whole-brain connectome and how the resulting r...
A new target for leptin
Tan et al. identify a population of leptin-responsive neurons that regulate food intake and body weight.
Issues of parcellation in the calculation of structure–function coupling
In their recent Review, Fotiadis and colleagues expertly summarized recent research on structure–func...
Reply to ‘Issues of parcellation in the calculation of structure–function coupling’
We appreciate the thoughtful Correspondence from A. Turnbull, F. V. Lin and Z. Zhang about our recent...
Innate immune control of synapse development
Innate lymphoid cells regulate inhibitory synapse formation in the mouse cortex during early postnatal life.
Structural neural plasticity evoked by rapid-acting antidepressant interventions
Structural neural plasticity evoked by rapid-acting antidepressant interventions
A feature in the pathophysiology of major depressive disorder (MDD), a mood disorder, is the impairment of excita...
Ruminating on replay during the awake state
In this Journal Club, Anna Gillespie discusses how the discovery of hippocampal replay during the awake state reshaped our...
mTOR and neuroinflammation in epilepsy: implications for disease progression and treatment
mTOR and neuroinflammation in epilepsy: implications for disease progression and treatment
Epilepsy remains a major health concern as anti-seizure medications frequently fail, and there is currently no treatment t...
Natural primate neurobiology
A new study captures nearly the full repertoire of primate natural behaviour and reveals that highly distributed cortical ...
A structural role for SynGAP
The synaptic protein SynGAP exerts its effects on synaptic plasticity via a structural role rather than its GTPase-activat...
Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases
Molecular and cellular mechanisms of selective vulnerability in neurodegenerative diseases
The selective vulnerability of specific neuronal subtypes is a hallmark of neurodegenerative diseases. In this Review, I s...
From compulsivity to compulsion: the neural basis of compulsive disorders
From compulsivity to compulsion: the neural basis of compulsive disorders
Compulsive behaviour, an apparently irrational perseveration in often maladaptive acts, is a potential transdiagnostic sym...
Key genes and convergent pathogenic mechanisms in Parkinson disease
Key genes and convergent pathogenic mechanisms in Parkinson disease
Parkinson disease (PD) is a neurodegenerative disorder marked by the preferential dysfunction and death of dopaminergic ne...
The language network as a natural kind within the broader landscape of the human brain
The language network as a natural kind within the broader landscape of the human brain
Language behaviour is complex, but neuroscientific evidence disentangles it into distinct components supported by dedicate...
Attentional capture
A large network of brain regions is involved in salient distractor processing.
Preparing for motherhood
In mice, specific pools of adult neural stem cells are recruited during pregnancy to support postpartum maternal behaviour.
The neurobiology of SARS-CoV-2 infection
The neurobiology of SARS-CoV-2 infection
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated 55–60% of those infected de...
The long COVID haul
Ongoing systemic and neurocognitive impairments that continue in a subset of individuals after infection with SARS-CoV-2 i...
The generative grammar of the brain: a critique of internally generated representations
The generative grammar of the brain: a critique of internally generated representations
The past decade of progress in neurobiology has uncovered important organizational principles for network preconfiguration...
Sleep and circadian rhythmicity as entangled processes serving homeostasis
Sleep and circadian rhythmicity as entangled processes serving homeostasis
Sleep is considered essential for the brain and body. A predominant concept is that sleep is regulated by circadian rhythm...
From local APP expression to network dysfunction
In mice, localized mutant APP expression in the CA3 hippocampal region leads to progressive network dysfunction and hippoc...
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