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Chemotherapeutic potential of radotinib against blood and solid tumors: A beacon of hope in drug repurposing
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Rational design and syntheses of naphthalimide-based fluorescent probes for targeted detection of diabetes biomarkers
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An overview of phenylsulfonylfuroxan-based nitric oxide donors for cancer treatment
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Current developments in PI3K-based anticancer agents: Designing strategies, biological activity, selectivity, structure-activity correlation, and docking insight
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Epidermal growth factor receptor mutations in breast Cancer: Therapeutic challenges and way forward
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Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design
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Beyond peptides: Unveiling the design strategies, structure activity correlations and protein-ligand interactions of small molecule inhibitors against PD-1/PD-L1
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Thiazole – A promising scaffold for antituberculosis agents and structure–activity relationships studies
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TDP1 represents a promising therapeutic target for overcoming tumor resistance to chemotherapeutic agents: progress and potential
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Targeting XPO1 for fighting relapsed/refractory diseases: The research progress of XPO1 inhibitors
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Multi-target directed ligands inspired natural products as an effective approach for the treatment of complex chronic health disorders
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Recent Advances in enhancer of zeste homolog 2 Inhibitors: Structural insights and therapeutic applications
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Tryptanthrins as multi-bioactive agents: discovery, diversity distribution and synthesis
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CDK4/6 inhibitors in HR-positive breast cancer immunotherapy
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A Review on zerumbone and its semisynthetic Analogs: Synthesis and Implications in Medicinal chemistry
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Protein arginine methyltransferase 7 modulators in disease therapy: Current progress and emerged opportunity
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Indoles as promising Therapeutics: A review of recent drug discovery efforts
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KAHA ligation as a platform for the rapid discovery of Protein Tyrosine phosphatase 1B (PTP1B) inhibitors
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Design and synthesis of JNK1-targeted PROTACs and research on the activity
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Enzyme fragment complementation driven by nucleic acid hybridization sans self-labeling protein
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Design, synthesis, and evaluation of dual son of sevenless 1 (SOS1) and epidermal growth factor receptor (EGFR) inhibitors for the treatment of cancers
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Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa
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Design and synthesis of novel mitochondria-targeted ergosterol peroxide derivatives as potential anti-cancer agents
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A dual-state emission luminogen for lipid droplet imaging and photodynamic therapy
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Discovery of the FXR/CES2 dual modulator LE-77 for the treatment of irinotecan-induced delayed diarrhea
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New stilbenes from Cajanus cajan inhibit adipogenesis in 3T3-L1 adipocytes through down-regulation of PPARγ
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Design, synthesis, molecular modeling and evaluation of 2,4-diaminopyrimidine analogues as promising colorectal cancer drugs
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Fluoroquinolones tackling antimicrobial resistance: Rational design, mechanistic insights and comparative analysis of norfloxacin vs ciprofloxacin derivatives
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A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 2: Non-DSM compounds
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Development of natural product-based targeted protein degraders as anticancer agents
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