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Differential induction of T-cell tolerance by tumour fibroblast subsets
Differential induction of T-cell tolerance by tumour fibroblast subsets
Many epithelial cancers are still immunotherapy-resistant [1]. A feature common to epithelial cancers is the infiltration ...
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment
Molecular mechanisms of tumour necrosis factor signalling via TNF receptor 1 and TNF receptor 2 in the tumour microenvironment
Tumour necrosis factor (TNF) is a primary mediator of inflammatory processes by facilitating cell death, immune cell activ...
Structure–function of type I and III interferons
Structure–function of type I and III interferons
The interferons (IFNs) are a family of innate immune cytokines that are central in providing a rapid response to pathogens...
Differential signaling by type-I and type-III interferons in mucosa
Differential signaling by type-I and type-III interferons in mucosa
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis
Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis
Interferons (IFNs) are soluble mediators of antiviral defense, with well-defined molecular mechanisms underlying their pro...
Editorial overview: The march of mucosal vaccines
Editorial overview: The march of mucosal vaccines
Dr. Meritxell Genescà is a senior investigator at the Infectious Diseases Department of the Vall d′Hebron Research Institu...
Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Recent advances in enterotoxin vaccine adjuvants
Recent advances in enterotoxin vaccine adjuvants
Enterotoxin adjuvants have been researched for their ability to promote immunity to co-delivered antigens. Outside of chol...
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity
AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity
The proper functioning of cytotoxic lymphocytes, such as natural killer and CD8+ T cells, is essential for effective cance...
Animal models of shigellosis: a historical overview
Animal models of shigellosis: a historical overview
Shigella spp. are major causative agents of bacillary dysentery, a severe enteric disease characterized by destruction and...