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Reduced Thioredoxin Regulates IL-1β Secretion via NLRP3 of IL-1β+ Alveolar Macrophages in COPD
Reduced Thioredoxin Regulates IL-1β Secretion via NLRP3 of IL-1β+ Alveolar Macrophages in COPD
To investigate the changes in the redox protein thioredoxin (TRX) in COPD and the role TRX plays in IL-1β release. Re...
The Role of EZH2 in Initiating Epigenetic Regulation of CRSwNP
The Role of EZH2 in Initiating Epigenetic Regulation of CRSwNP
In the present study, we aimed to identify biomarkers and pathways associated with the pathogenesis of CRSwNP.
The Role of Type 2 Innate Lymphoid Cells in Adenoid Hypertrophy with Allergic Rhinitis Among Children and Related Potential Therapeutic Targets
The Role of Type 2 Innate Lymphoid Cells in Adenoid Hypertrophy with Allergic Rhinitis Among Children and Related Potential Therapeutic Targets
This study aims to identify potential therapeutic targets for AH therapy based on investigation of distribution and functi...
Immune Cell Characteristics in a Gut-Kidney Axis-Induced Mouse Model of IgA Nephropathy: The Upregulated Dendritic Cells and Neutrophils
Immune Cell Characteristics in a Gut-Kidney Axis-Induced Mouse Model of IgA Nephropathy: The Upregulated Dendritic Cells and Neutrophils
Mapping mucosal immune cells in IgA nephropathy influenced by gut microbiota, investigating the role of innate immune cell...
Amentoflavone Impedes NF-κB Activation and Mediates Apoptosis Induction in Lung Cancer Cells: An in vitro and in silico exploration
Amentoflavone Impedes NF-κB Activation and Mediates Apoptosis Induction in Lung Cancer Cells: An in vitro and in silico exploration
Investigating the anticancer potential of AMF in A549 cells, focusing on its unique dual role in NF-κB suppression a...
Developing an Interpretable Machine Learning Model for Early Prediction of Cardiovascular Involvement in Systemic Lupus Erythematosus
Developing an Interpretable Machine Learning Model for Early Prediction of Cardiovascular Involvement in Systemic Lupus Erythematosus
Identifying key factors associated with cardiac involvement in SLE and to develop an interpretable machine learning (ML) m...
Sepsis with Cancer is Marked by a Dysregulated Myeloid Cell Compartment: A Pilot Study
Sepsis with Cancer is Marked by a Dysregulated Myeloid Cell Compartment: A Pilot Study
A pilot studying investigating and highlighting the complex interplay between sepsis and cancer on immune cell function an...
The Prognostic Value of Neutrophil-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio in Patients with Hepatocellular Carcinoma Receiving HAIC-Based Conversion Hepatectomy: A Dual-Center Retrospective Cohort Study
The Prognostic Value of Neutrophil-to-Lymphocyte Ratio and Lymphocyte-to-Monocyte Ratio in Patients with Hepatocellular Carcinoma Receiving HAIC-Based Conversion Hepatectomy: A Dual-Center Retrospective Cohort Study
Evaluation of prognostic significance of neutrophil-to-lymphocyte ratio & lymphocyte-to-monocyte ratio in patients wit...
Oral Health and Diabetic Cardiomyopathy: Mechanisms, Biomarkers, and Early Screening Approaches
Oral Health and Diabetic Cardiomyopathy: Mechanisms, Biomarkers, and Early Screening Approaches
Oral Health and Diabetic Cardiomyopathy: Mechanisms, Biomarkers, and Early Screening Approaches
Unveiling PANoptosis in Acute Kidney Injury: An Integrative Multi-Dimensional Approach to Identify Key Biomarkers
Unveiling PANoptosis in Acute Kidney Injury: An Integrative Multi-Dimensional Approach to Identify Key Biomarkers
In this study scRNA-seq was employed to find differentially expressed genes associated with apoptosis, pyroptosis, and nec...
Electroacupuncture at ST36 Treatment Suppresses the Microglial Pyroptosis Through Activating α7nAChR in a Rat Model of Asphyxial Cardiac Arrest
Electroacupuncture at ST36 Treatment Suppresses the Microglial Pyroptosis Through Activating α7nAChR in a Rat Model of Asphyxial Cardiac Arrest
Investigating if Electroacupuncture at ST36 treatment suppresses the microglial pyroptosis through activating α7nACh...
TMAO Induces Vascular Endothelial Cells Pyroptosis Through TET2-CYTB-ROS Pathway
TMAO Induces Vascular Endothelial Cells Pyroptosis Through TET2-CYTB-ROS Pathway
TMAO promotes the methylation level of the CYTB gene promoter and down-regulates the expression of CYTB by inhibiting the ...
Association Between Thymosin β4 and Coronary Arterial Lesions in Children with Kawasaki Disease
Association Between Thymosin β4 and Coronary Arterial Lesions in Children with Kawasaki Disease
Study explores Thymosin β4's role in Kawasaki disease, examining its relationship to inflammation and coronary artery...
Zhongfeng Xingnao Liquid Ameliorated the Early Impairment of Intracerebral Hemorrhage by Inhibiting NF-κB/NLRP3 Axis in Rats
Zhongfeng Xingnao Liquid Ameliorated the Early Impairment of Intracerebral Hemorrhage by Inhibiting NF-κB/NLRP3 Axis in Rats
The optimal timing for ZFXN administration within hours of symptom onset and its underlying mechanisms, focusing on NF-&ka...
The Prognostic Value of Platelet-to-Lymphocyte Ratio and Tricuspid Regurgitation Velocity in Patients with Light-Chain Myocardial Amyloidosis
The Prognostic Value of Platelet-to-Lymphocyte Ratio and Tricuspid Regurgitation Velocity in Patients with Light-Chain Myocardial Amyloidosis
To explore the prognostic value of inflammatory indexes and novel echocardiographic parameters in Light-chain myocardial a...
Danshensu Ethyl Ester Alleviates LPS-Induced Acute Lung Injury by Targeting the NLRP3 Inflammasome
Danshensu Ethyl Ester Alleviates LPS-Induced Acute Lung Injury by Targeting the NLRP3 Inflammasome
DEE exerts an inhibitory influence on the LPS-induced inflammatory response by suppressing the activation of the NLRP3 inf...
Multi-Omics Analysis and Validation of Cell Senescence-Related Genes Associated with Non-Alcoholic Fatty Liver Disease
Multi-Omics Analysis and Validation of Cell Senescence-Related Genes Associated with Non-Alcoholic Fatty Liver Disease
Assessing causal links between senescence-related genes and non-alcoholic fatty liver disease using summary-data Mendelian...
From Microbial Homeostasis to Systemic Pathogenesis: A Narrative Review on Gut Flora’s Role in Neuropsychiatric, Metabolic, and Cancer Disorders
From Microbial Homeostasis to Systemic Pathogenesis: A Narrative Review on Gut Flora’s Role in Neuropsychiatric, Metabolic, and Cancer Disorders
This review focuses on analyzing relationships between gut microbial communities and four major disease spectra
Mechanisms and Targeted Therapeutic Strategies in Sepsis-Induced Myocardial Dysfunction: The Role of NLRP3 Inflammasome-Mediated Inflammation
Mechanisms and Targeted Therapeutic Strategies in Sepsis-Induced Myocardial Dysfunction: The Role of NLRP3 Inflammasome-Mediated Inflammation
Targeting the NLRP3 inflammasome represents a promising therapeutic approach and an important area for future research. Re...
Prediction for Acute Biliary Pancreatitis After Laparoscopic Cholecystectomy
Prediction for Acute Biliary Pancreatitis After Laparoscopic Cholecystectomy
This study aims to develop a predictive model for assessing the risk of post- Laparoscopic cholecystectomy pancreatitis in...
The Role of Pentraxin 3 in the Assessment of Cardiovascular Risk and Disease Activity in Patients with Rheumatoid Arthritis and Spondyloarthritis
The Role of Pentraxin 3 in the Assessment of Cardiovascular Risk and Disease Activity in Patients with Rheumatoid Arthritis and Spondyloarthritis
Relationships were observed between PTX3 levels and markers of RA activity. However, no such relationships were identified...
Bilateral Patent Processus Vaginalis with Chylous Effusion in a Pediatric Patient: A Rare Case Report and Literature Review
Bilateral Patent Processus Vaginalis with Chylous Effusion in a Pediatric Patient: A Rare Case Report and Literature Review
To report a rare case of bilateral patent processus vaginalis with chylous effusion in a pediatric patient
5-Methoxytryptophan Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating Nrf2-Mediated Mitophagy
5-Methoxytryptophan Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating Nrf2-Mediated Mitophagy
5-Methoxytryptophan Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating Nrf2-Mediated Mitophagy
A Neutrophil Extracellular Traps-Related Gene Trait Revealed the Prospective Therapy Strategy of Coronary Atherosclerosis
A Neutrophil Extracellular Traps-Related Gene Trait Revealed the Prospective Therapy Strategy of Coronary Atherosclerosis
Independent NETDEG trait in CA, offering insights into potential biomarkers and therapeutic targets for combating this dis...
Sepsis-Induced Endothelial Dysfunction: Permeability and Regulated Cell Death
Sepsis-Induced Endothelial Dysfunction: Permeability and Regulated Cell Death
Summarizing recent research progress on factors, mechanisms that may affect permeability and regulated cell death of Endot...
Regulation of Inflammation, Lipid Metabolism, and Liver Fibrosis by Core Genes of M1 Macrophages in NASH
Regulation of Inflammation, Lipid Metabolism, and Liver Fibrosis by Core Genes of M1 Macrophages in NASH
Identifying differential immune cell profiles between normal liver and NASH specimens using the CIBERSORT algorithm. read ...
Association Between Albumin Levels and Neonatal Acute Respiratory Distress Syndrome in Newborn Pneumoniae
Association Between Albumin Levels and Neonatal Acute Respiratory Distress Syndrome in Newborn Pneumoniae
Investigating the relationship between serum albumin levels and neonatal acute respiratory distress syndrome in patients w...
Dissecting Innate and Adaptive Immunity in Inflammatory Bowel Disease: Immune Compartmentalization, Microbiota Crosstalk, and Emerging Therapies
Dissecting Innate and Adaptive Immunity in Inflammatory Bowel Disease: Immune Compartmentalization, Microbiota Crosstalk, and Emerging Therapies
Discussing the important role of innate and adaptive immunity in the development of and inflammatory bowel disease.
Sodium Propionate Alleviates Atopic Dermatitis by Inhibiting Ferroptosis via Activation of LTBP2/FABP4 Signaling Pathway
Sodium Propionate Alleviates Atopic Dermatitis by Inhibiting Ferroptosis via Activation of LTBP2/FABP4 Signaling Pathway
Sodium propionate may alleviate atopic dermatitis symptoms by modulating ferroptosis through the LTBP2/FABP4 pathway
Inflammatory and Nutritional Markers as Indicators for Diagnosing and Assessing Disease Activity in MS and NMOSD
Inflammatory and Nutritional Markers as Indicators for Diagnosing and Assessing Disease Activity in MS and NMOSD
This study seeks to probe the expression of these markers in patients with MS and NMOSD.
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