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Impact of a standardized emergency department asthma care pathway on health services utilization
Impact of a standardized emergency department asthma care pathway on health services utilization
An evidence-based standardized ED asthma care pathway (EDACP) was developed and implemented in Ontario, Canada. To determi...
Sputum immunoglobulin E levels correlate with eosinophilic airway regardless of atopy
Sputum immunoglobulin E levels correlate with eosinophilic airway regardless of atopy
Immunoglobulin E (IgE) is a key molecule that induces mast cell activation in allergic inflammation and contributes to typ...
Online food allergy and anaphylaxis education for school personnel is effective and scalable: experience with the allergyaware e-learning portal from 2015 to 2022
Online food allergy and anaphylaxis education for school personnel is effective and scalable: experience with the allergyaware e-learning portal from 2015 to 2022
Providing training to school personnel on how to prevent, recognize, and manage anaphylaxis is critical. Asynchronous e-le...
Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK
Prevalence trends and risk factors for allergic rhinoconjunctivitis, asthma and eczema in the UK
Allergic rhinoconjunctivitis (ARC), asthma and eczema carry a substantial morbidity. These conditions often co-exist withi...
Safety and adherence of early oral immunotherapy for peanut allergy in a primary care setting: a retrospective cross-sectional study
Safety and adherence of early oral immunotherapy for peanut allergy in a primary care setting: a retrospective cross-sectional study
Peanut allergy is a common food allergy with potentially life-threatening implications. Early oral immunotherapy for peanu...
A case report of fatal anaphylaxis on first exposure to rasburicase just before lymphoma treatment
A case report of fatal anaphylaxis on first exposure to rasburicase just before lymphoma treatment
Rasburicase, a recombinant urate oxidase enzyme, has potent efficacy in controlling uric acid and is widely used to preven...
Zéro allergie research clinic: a clinical and research initiative in oral immunotherapy for managing IgE-mediated food allergy
Zéro allergie research clinic: a clinical and research initiative in oral immunotherapy for managing IgE-mediated food allergy
The Zéro allergie research clinic (Saguenay, Canada) is a clinical and research initiative in oral immunotherapy (OIT...
Efficacy of probiotics as adjuvant therapy in bronchial asthma: a systematic review and meta-analysis
Efficacy of probiotics as adjuvant therapy in bronchial asthma: a systematic review and meta-analysis
Asthma is a chronic, heterogeneous disease characterized by airway inflammation. Asthma exacerbations significantly increa...
Focused allergic rhinitis practice parameter for Canada
Focused allergic rhinitis practice parameter for Canada
Allergic rhinitis (AR) is a prevalent disease in Canada that affects both children and adults. Several guidelines for the ...
Exploratory pharmacodynamics and efficacy of PF-06817024 in a Phase 1 study of patients with chronic rhinosinusitis and atopic dermatitis
Exploratory pharmacodynamics and efficacy of PF-06817024 in a Phase 1 study of patients with chronic rhinosinusitis and atopic dermatitis
PF-06817024 is a humanized antibody against interleukin-33 that has the potential to inhibit type 2 inflammation. An explo...
fSCIG 10% in pediatric primary immunodeficiency diseases: a European post-authorization safety study
fSCIG 10% in pediatric primary immunodeficiency diseases: a European post-authorization safety study
The safety, tolerability, and immunogenicity of hyaluronidase-facilitated subcutaneous immunoglobulin (fSCIG) 10% (dual-vi...
Effectiveness of immunoglobulin replacement therapy in preventing infections in patients with chronic obstructive pulmonary disease: a systematic review
Effectiveness of immunoglobulin replacement therapy in preventing infections in patients with chronic obstructive pulmonary disease: a systematic review
Immunoglobulin replacement therapy is a standard treatment for patients with antibody production deficiencies, which is of...
A survey of severe asthma in Canada: results from the CASCADE practice reflective program
A survey of severe asthma in Canada: results from the CASCADE practice reflective program
Since the last guidance was published by the Canadian Thoracic Society, there have been several advances in the clinical m...
Genetic links between atopy, allergy, and alopecia areata: insights from a Mendelian randomization study
Genetic links between atopy, allergy, and alopecia areata: insights from a Mendelian randomization study
Alopecia areata (AA), a prevalent form of autoimmune hair loss, has a not well-defined relationship with atopic and allerg...
Sublingual immunotherapy for allergy to shrimp: the nine-year clinical experience of a Midwest Allergy-Immunology practice
Sublingual immunotherapy for allergy to shrimp: the nine-year clinical experience of a Midwest Allergy-Immunology practice
Diet restrictions and fear of adverse reactions put a significant burden on the nutrition, growth and life style of childr...
Comparison of cytokine expression and disease severity between plasma cell-dominant and eosinophil-dominant patients in chronic rhinosinusitis with nasal polyps
Comparison of cytokine expression and disease severity between plasma cell-dominant and eosinophil-dominant patients in chronic rhinosinusitis with nasal polyps
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease characterized by inflammation of the nasal an...
Patient outcomes associated with subcutaneous C1INH prophylaxis for hereditary angioedema: a retrospective analysis
Patient outcomes associated with subcutaneous C1INH prophylaxis for hereditary angioedema: a retrospective analysis
Real-world data on subcutaneous C1INH (C1INH[SC]) usage and patient-level impacts on hereditary angioedema (HAE)-related o...
Biologic use and treatment patterns in patients with chronic rhinosinusitis with nasal polyps: a US real-world study
Biologic use and treatment patterns in patients with chronic rhinosinusitis with nasal polyps: a US real-world study
Several biologics are now approved in the US as add-on treatments for chronic rhinosinusitus with nasal polyps (CRSwNP). T...
Successful use of dupilumab for egg-induced eosinophilic gastroenteritis with duodenal ulcer: a pediatric case report and review of literature
Successful use of dupilumab for egg-induced eosinophilic gastroenteritis with duodenal ulcer: a pediatric case report and review of literature
Non-esophageal eosinophilic gastrointestinal disorder (non-EoE-EGID) is a rare disease in which eosinophils infiltrate par...
Diagnostic validity of specific immunoglobulin E levels to alpha-gal in alpha-gal syndrome: a cross-sectional analysis
Diagnostic validity of specific immunoglobulin E levels to alpha-gal in alpha-gal syndrome: a cross-sectional analysis
The diagnosis of Alpha-gal Syndrome (AGS) is based on the presence of symptoms after being exposed to potential sources of...
Presence of variable extrathoracic airflow limitation in patients with a negative methacholine challenge test
Presence of variable extrathoracic airflow limitation in patients with a negative methacholine challenge test
Determine whether variable extrathoracic airflow limitation (VEAL) is observed in patients with negative methacholine chal...
Infantile atopic dermatitis and maternal-infant bonding: a mixed methods study
Infantile atopic dermatitis and maternal-infant bonding: a mixed methods study
Childhood atopic dermatitis can have a negative effect on caregivers’ quality of life and stress levels due to the b...
Quality of life is lower in food allergic adolescents compared to young children at a community educational symposium
Quality of life is lower in food allergic adolescents compared to young children at a community educational symposium
Food allergies (FA) can detrimentally impact physical, emotional, and psychological quality of life (QoL) among pediatric ...
Human placental extract suppresses mast cell activation and induces mast cell apoptosis
Human placental extract suppresses mast cell activation and induces mast cell apoptosis
Human placental extract (HPE) has been documented to facilitate the healing of certain disorders including allergy. Howeve...
Helicobacter pylori infection attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in C57/BL6 mice
Helicobacter pylori infection attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in C57/BL6 mice
Although numerous studies have suggested a negative correlation between Helicobacter pylori (H. pylori) infection and alle...
Sensitization to avian and fungal proteins in different work environments
Sensitization to avian and fungal proteins in different work environments
Hypersensitivity pneumonitis (HP) is usually caused by the inhalation of avian and fungal proteins. The present study asse...
Osimertinib tolerance in a patient with Stevens Johnson syndrome during osimertinib therapy after treatment with pembrolizumab
Osimertinib tolerance in a patient with Stevens Johnson syndrome during osimertinib therapy after treatment with pembrolizumab
Osimertinib has emerged as an important tool in the treatment of non-small cell lung cancers (NSCLC) with certain activati...
Safety and effectiveness of the Canadian food ladders for children with IgE-mediated food allergies to cow’s milk and/or egg
Safety and effectiveness of the Canadian food ladders for children with IgE-mediated food allergies to cow’s milk and/or egg
Food ladders are tools designed to facilitate home-based dietary advancement in children with food allergies through stepw...
Validation of adult asthma case definitions for primary care sentinel surveillance
Validation of adult asthma case definitions for primary care sentinel surveillance
Most asthma diagnoses and patient care take place in primary care settings. Electronic medical records (EMRs) offer an opp...
Fatal eosinophilic myocarditis and submassive hepatic necrosis in lamotrigine induced DRESS syndrome
Fatal eosinophilic myocarditis and submassive hepatic necrosis in lamotrigine induced DRESS syndrome
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a rare but severe and sometimes fatal adverse dr...
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