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Comparative study of the inhibitory effects of different antibiotic administration routes on bone healing in a rat tibial infection model
IntroductionBone infections, especially osteomyelitis, are significant complication in orthopedic surgery and pose substan...
Virology, epidemiology, transmissions, diagnostic tests, prophylaxis and treatments of human Mpox: Saudi Arabia perspective
1 IntroductionMpox (previously known as monkeypox) is a viral infectious disease caused by the Mpox virus (MPXV), which is...
Establishment of a novel double-antibody sandwich fluorescence microsphere immunochromatographic test strip for rapid detection of swine acute diarrhea syndrome coronavirus (SADS-CoV) infection
1 IntroductionCoronaviruses, a type of positive-sense, single-stranded RNA virus, belong to the order Nidovirales, family ...
First environmental survey of Scedosporium species in Lebanon
1 IntroductionScedosporium species are emerging opportunistic pathogens causing a wide variety of infections in humans. De...
Antibacterial and antibiofilm activities of star anise-cinnamon essential oil against multidrug-resistant Salmonella Thompson
1 IntroductionSalmonella represents a significant threat to global public health as an important zoonotic disease pathogen...
Targeting CD4+ T cells through gut microbiota: therapeutic potential of traditional Chinese medicine in inflammatory bowel disease
1 IntroductionInflammatory Bowel Disease (IBD) is a chronic, immune-mediated gastrointestinal disorder characterized by re...
Editorial: Global excellence in fungal pathogenesis: Asia & Australasia
Fungi are an integral part of our ecosystem, playing key roles in decomposition and nutrient cycling. However, a subset of...
Macrolide resistance in Mycoplasma pneumoniae in adult patients
1 IntroductionMycoplasma pneumoniae is one of the most significant pathogens responsible for respiratory infections in hum...
Investigating the Gut Microbiota Profile in Prehypertensive Individuals Exhibiting Phlegm-Dampness Constitution
1 IntroductionHypertension is a common chronic disease, a major risk factor for cardiovascular and cerebrovascular disease...
Significance of the gut tract in the therapeutic mechanisms of polydopamine for acute cerebral infarction: neuro-immune interaction through the gut-brain axis
1 IntroductionStroke, which is also known as a cerebrovascular accident, is a prevalent cerebrovascular disease and ranks ...
Optimized oxygen therapy improves sleep deprivation-induced cardiac dysfunction through gut microbiota
1 IntroductionIn human life, every individual spends approximately one-third of our time sleeping (Sang et al., 2023). Thi...
Rapid detection of Mycoplasma pneumoniae CARDS toxin in clinical respiratory specimens by a loop-mediated isothermal amplification assay
1 IntroductionMycoplasma pneumoniae (MP) is one of the most prevalent pathogens responsible for respiratory diseases. It i...
Enterobactin and salmochelin S4 inhibit the growth of Staphylococcus aureus
IntroductionNew antimicrobial molecules, especially with innovative modes of action, are urgently needed to tackle the ant...
Identification and phylogenetic characterization of novel hunnivirus recombinant strains in cattle from Guangxi, China
1 IntroductionHunnivirus(HuV) is a single-stranded positive-sense RNA virus belonging to the genus HuV A within the Picorn...
Clinical characteristics, molecular epidemiology and mechanisms of colistin heteroresistance in Enterobacter cloacae complex
1 IntroductionEnterobacter cloacae complex (ECC) has emerged as one of the leading causes of nosocomial infections worldwi...
Standardization of 16S rRNA gene sequencing using nanopore long read sequencing technology for clinical diagnosis of culture negative infections
IntroductionAmplicon-based sequencing techniques targeting the 16S ribosomal RNA gene (16S rRNA) are crucial for identifyi...
Massa Medicata Fermentata treated spleen deficiency constipation by mediating intestinal microbiota and serum peptide
1 IntroductionConstipation is a prevalent gastrointestinal disorder with a worldwide prevalence of 16%, and in China, 20%–...
Editorial: Developing therapeutics for antimicrobial resistant pathogens: volume II
Antimicrobial resistance (AMR) is one of the most pressing global public health challenges, with bacterial AMR alone direc...
Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization
IntroductionSepsis is a major cause of morbidity and mortality for critically ill patients worldwide. It’s estimated that ...
Deconstruct the link between gut microbiota and neurological diseases: application of Mendelian randomization analysis
1 IntroductionThe fields of neurology and microbiology have followed separate paths of development, with little convergenc...
Non-tuberculous mycobacteria enhance the tryptophan-kynurenine pathway to induce immunosuppression and facilitate pulmonary colonization
IntroductionNon-tuberculous mycobacteria (NTM) are highly prevalent in soil and water ecosystems, and their incidence in h...
Genomic epidemiology and evolutionary dynamics of the Omicron variant of SARS-CoV-2 during the fifth wave of COVID-19 in Pakistan
1 IntroductionThe coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronaviru...
Apoptosis, inflammatory and innate immune responses induced by infection with a novel goose astrovirus in goose embryonic kidney cells
1 IntroductionIn recent years, a highly lethal case of visceral gout, which is characterized by visceral urate deposition,...
Alternative splicing in the genome of HPV and its regulation
1 IntroductionCervical cancer is the fourth most common cancer among women worldwide. In 2020, the disease resulted in ove...
Novel antimicrobial coating for hernia meshes
IntroductionHernia repair is one of the most frequently performed surgical procedures worldwide. Current hernia guidelines...
Risk factors for identifying pneumocystis pneumonia in pediatric patients
IntroductionPneumocystis pneumonia (PCP) is a fungal infectious disease of the respiratory system caused by Pneumocystis j...
Non-classical monocyte levels correlate negatively with HIV-associated cerebral small vessel disease and cognitive performance
Non-classical monocyte levels correlate negatively with HIV-associated cerebral small vessel disease and cognitive performance
IntroductionHIV-associated age-related comorbidities have a taken a center-stage in the management of this disease, owing ...
Target antigen screening and development of a multi-component subunit vaccine against Mycoplasma synoviae in chickens
1 IntroductionMycoplasma synoviae (MS) is a pathogen that poses a substantial threat to the poultry industry worldwide, ha...
Brucella mediates autophagy, inflammation, and apoptosis to escape host killing
1 IntroductionBrucellosis is a prevalent, chronic infectious disease caused by the bacterium Brucella. So far, twelve Bruc...
Changes functional prediction of ear canal flora in chronic bacterial otitis externa
1 IntroductionAll organs of the human body have a large number and variety of microorganisms (Postler and Ghosh, 2017). Th...
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